Tom Fite Paine

BRAIN ABSCESS AND MENINGITIS ASSOCIATED WITH A PLEUROPNEUMONIA-LIKE ORGANISM: CLINICAL AND BACTERIOLOGICAL OBSERVATIONS IN A CASE WITH RECOVERY

Excerpt The role of the pleuropneumonia group of microorganisms as human pathogens is still far from clear. In the case reported here a pleuropneumonia-like organism was repeatedly cultured from th...

Streptomycin treatment of urinary tract infections, with special reference to the use of alkali.

T HERE are a number of reports on the streptomycin treatment of urinary tract infections caused by susceptible gram-negative organisms.‘-9 The clinical results have been quite variable. Some authors have advocated alkalinization of the urine during streptomycin therapy,8~10*11 but to date there have been no convincing data to indicate that the clinical results of streptomycin therapy are favorably influenced by alkalinization of the urine. The purpose of this report is to present clinical and bacteriological observations in twentyone streptomycin-treated patients with urinary tract infections, of whom fourteen were also treated with alkalis.

AUREOMYCIN—A NEW ANTIBIOTIC: EVALUATION OF ITS EFFECTS IN TYPHOID FEVER, SEVERE SALMONELLA INFECTIONS AND IN A CASE OF COLON BACILLUS BACTEREMIA

Excerpt There has been a notable lack of success in the treatment of typhoid fever and salmonella infections with the chemotherapeutic and antibiotic agents that are now available. This has been tr...

Streptomycin in the treatment of meningitis: report of 27 cases treated at the Boston City Hospital.

Excerpt Cases of meningitis due toMycobacterium tuberculosisor to gram-negative bacilli are not particularly frequent. They are nevertheless of great importance because of their high mortality and ...

Urinary Excretion of Aureomycin.

Summary After a single oral dose of 0.5 or 0.75 g of aureomycin given to fasting normal subjects antibiotic activity was recovered in the urine for more than 33 to 55 hours. The antibiotic was excreted in high concentrations between 2 and 16 hours and the largest rate of excretion occurred between 2 and 8 hours. The findings suggest that the optimum intervals between oral doses of aureomycin should be about 8 hours.