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Dive into the research topics where Tom T. Little is active.

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Featured researches published by Tom T. Little.


Health Physics | 2002

Using exact Poisson likelihood functions in Bayesian interpretation of counting measurements.

Guthrie Miller; Harry F. Martz; Tom T. Little; Ray Guilmette

A technique for computing the exact marginalized (integrated) Poisson likelihood function for counting measurement processes involving a background subtraction is described. An empirical Bayesian method for determining the prior probability distribution of background count rates from population data is recommended and would seem to have important practical advantages. The exact marginalized Poisson likelihood function may be used instead of the commonly used Gaussian approximation. Differences occur in some cases of small numbers of measured counts, which are discussed. Optional use of exact likelihood functions in our Bayesian internal dosimetry codes has been implemented using an interpolation-table approach, which means that there is no computation time penalty except for the initial setup of the interpolation tables.


Health Physics | 2009

METHODS USED TO CALCULATE DOSES RESULTING FROM INHALATION OF CAPSTONE DEPLETED URANIUM AEROSOLS

Guthrie Miller; Yung Sung Cheng; Richard J. Traub; Tom T. Little; Raymond A. Guilmette

The methods used to calculate radiological and toxicological doses to hypothetical persons inside either a U.S. Army Abrams tank or Bradley Fighting Vehicle that has been perforated by depleted uranium munitions are described. Data from time- and particle-size-resolved measurements of depleted uranium aerosol as well as particle-size-resolved measurements of aerosol solubility in lung fluids for aerosol produced in the breathing zones of the hypothetical occupants were used. The aerosol was approximated as a mixture of nine monodisperse (single particle size) components corresponding to particle size increments measured by the eight stages plus the backup filter of the cascade impactors used. A Markov Chain Monte Carlo Bayesian analysis technique was employed, which straightforwardly calculates the uncertainties in doses. Extensive quality control checking of the various computer codes used is described.


Radiation Protection Dosimetry | 2001

Bayesian prior probability distributions for internal dosimetry

Guthrie Miller; W.C. Inkret; Tom T. Little; H.F. Martz; M.E. Schillaci


Radiation Protection Dosimetry | 2002

Bayesian Internal Dosimetry Calculations Using Markov Chain Monte Carlo

Guthrie Miller; H.F. Martz; Tom T. Little; R. Guilmette


Health Physics | 2000

Analyzing bioassay data using Bayesian methods -- A primer

Guthrie Miller; William C. Inkret; Mario E. Schillaci; Harry F. Martz; Tom T. Little


Radiation Protection Dosimetry | 2003

The application of Bayesian techniques in the interpretation of bioassay data

Guthrie Miller; Tom T. Little; R. Guilmette


Health Physics | 2008

BAYESIAN HYPOTHESIS TESTING-USE IN INTERPRETATION OF MEASUREMENTS

Guthrie Miller; Harry F. Martz; Tom T. Little; Luiz Bertelli


Radiation Protection Dosimetry | 2007

Technical basis for using nose swab bioassay data for early internal dose assessment

R. Guilmette; Luiz Bertelli; Guthrie Miller; Tom T. Little


Radiation Protection Dosimetry | 2007

Uranium dose assessment: a Bayesian approach to the problem of dietary background.

Tom T. Little; Guthrie Miller; R. Guilmette; Luiz Bertelli


Radiation Protection Dosimetry | 2007

Comparison of dose estimation from occupational exposure to 239Pu using different modelling approaches

S. A. Romanov; R. Guilmette; V. F. Khokhryakov; A. W. Phipps; E. E. Aladova; Luiz Bertelli; A. Birchall; Keith F. Eckerman; V. V. Khokhryakov; Melinda P. Krahenbuhl; Richard Wayne Leggett; Tom T. Little; Guthrie Miller; Scott C. Miller; A. Riddell; K. G. Suslova; V. V. Vostrotin; Ye. V. Zaytseva

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Guthrie Miller

Los Alamos National Laboratory

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R. Guilmette

Los Alamos National Laboratory

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Luiz Bertelli

Los Alamos National Laboratory

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Harry F. Martz

Los Alamos National Laboratory

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Mario E. Schillaci

Los Alamos National Laboratory

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William C. Inkret

Los Alamos National Laboratory

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Keith F. Eckerman

Oak Ridge National Laboratory

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Raymond A. Guilmette

Lovelace Respiratory Research Institute

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Richard Wayne Leggett

Oak Ridge National Laboratory

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