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Dive into the research topics where Tomio Arai is active.

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Featured researches published by Tomio Arai.


Atherosclerosis | 2003

Hepatitis C virus seropositivity, but not hepatitis B virus carrier or seropositivity, associated with increased pulse wave velocity.

Hirofumi Tomiyama; Tomio Arai; Kenichi Hirose; Sabroh Hori; Yoshio Yamamoto; Akira Yamashina

Immune mechanisms have important roles in the pathogenesis of atherosclerosis. The present study was conducted to evaluate the association of pulse wave velocity (PWV) with either hepatitis C or B. In 7514 subjects, we determined the PWV, as well as the plasma levels of hepatitis B virus antigen and antibody and of hepatitis C virus antibody. The results of multiple regression analysis showed that seropositivity for hepatitis C virus was a significant variable for PWV independent from atherosclerotic risk factors. Thus, hepatitis C virus seropositivity was associated with increased PWV.


American Journal of Cardiology | 1999

Detection of silent myocardial ischemia patients by the spatial velocity electrocardiogram.

Akihiko Sasaki; Tomio Arai; Hiroshi Shigeta; Chiharu Ibukiyama

This study was designed to detect patients with type I silent myocardial ischemia (SMI) at rest by assessing the symmetry of the electrocardiographic (ECG) T wave using the spatial velocity electrocardiogram (SVECG). In this study, the ECG T waves in patients with SMI were symmetric compared with those in normal subjects, and the the c/a ratio in the SVECG-T wave as the index of degree of symmetry of the ECG T wave enabled us to diagnose 73% of these patients; the c/a ratio in the SVECG T wave was a useful index for detecting patients with type I SMI at rest.


Hypertension Research | 2002

Validity, Reproducibility, and Clinical Significance of Noninvasive Brachial-Ankle Pulse Wave Velocity Measurement

Akira Yamashina; Hirofumi Tomiyama; Kazuhiro Takeda; Hideichi Tsuda; Tomio Arai; Kenichi Hirose; Yutaka Koji; Saburoh Hori; Yoshio Yamamoto


Atherosclerosis | 2003

Influences of age and gender on results of noninvasive brachial–ankle pulse wave velocity measurement—a survey of 12 517 subjects

Hirofumi Tomiyama; Akira Yamashina; Tomio Arai; Kenichi Hirose; Yutaka Koji; Taishiro Chikamori; Saburoh Hori; Yoshio Yamamoto; Nobutaka Doba; Shigeaki Hinohara


Hypertension Research | 2003

Brachial-Ankle Pulse Wave Velocity as a Marker of Atherosclerotic Vascular Damage and Cardiovascular Risk

Akira Yamashina; Hirofumi Tomiyama; Tomio Arai; Kenichi Hirose; Yutaka Koji; Yoji Hirayama; Yoshio Yamamoto; Saburoh Hori


Atherosclerosis | 2006

Menopause is an independent factor augmenting the age-related increase in arterial stiffness in the early postmenopausal phase

Gulnisa Zaydun; Hirofumi Tomiyama; Hideki Hashimoto; Tomio Arai; Yutaka Koji; Minoru Yambe; Kohki Motobe; Saburou Hori; Akira Yamashina


Hypertension Research | 2003

Nomogram of the Relation of Brachial-Ankle Pulse Wave Velocity with Blood Pressure

Akira Yamashina; Hirofumi Tomiyama; Tomio Arai; Yutaka Koji; Minoru Yambe; Hiroaki Motobe; Zydem Glunizia; Yoshio Yamamoto; Saburoh Hori


The Journal of Clinical Endocrinology and Metabolism | 2003

Increased Pulse Wave Velocity Associated with Reduced Calcaneal Quantitative Osteo-sono Index: Possible Relationship Between Atherosclerosis and Osteopenia

Kenichi Hirose; Hirofumi Tomiyama; Ryo Okazaki; Tomio Arai; Yutaka Koji; Gulnisa Zaydun; Saburo Hori; Akira Yamashina


Circulation | 2005

Cut-Off Value of the Ankle-Brachial Pressure Index at Which the Accuracy of Brachial-Ankle Pulse Wave Velocity Measurement is Diminished

Koki Motobe; Hirofumi Tomiyama; Yutaka Koji; Minoru Yambe; Zaydun Gulinisa; Tomio Arai; Hiroaki Ichihashi; Tsuneyuki Nagae; Shin Ishimaru; Akira Yamashina


Hypertension Research | 2004

The age-related increase in arterial stiffness is augmented in phases according to the severity of hypertension.

Hirofumi Tomiyama; Tomio Arai; Yutaka Koji; Minoru Yambe; Kohki Motobe; Glunisa Zaydun; Yoshio Yamamoto; Saburoh Hori; Akira Yamashina

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Kenichi Hirose

Tokyo Medical University

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Minoru Yambe

Tokyo Medical University

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Yutaka Koji

Tokyo Medical University

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Akihiko Sasaki

Tokyo Medical University

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Koki Motobe

Tokyo Medical University

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