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Tomoharu Sano

Hokkaido University

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Featured researches published by Tomoharu Sano.

Nucleosides, Nucleotides & Nucleic Acids | 1983

Structure of 2′,3′-0-Isopropylidene-6-cyanouridine

Yuriko Yamagata; Yukari Kobayashi; Nobuo Okabe; Ken-ichi Tomita; Tomoharu Sano; Hideo Inoue; Tohru Ueda

Abstract The crystal and molecular structure of the title compound has been determined by the X-ray diffraction method. Crystals belong to the orthorhombic space group P212121 and the cell dimensions are a=7.832(1), b=20.466(2) and c=9.159(1) A. The structure was solved by direct methods and refined by the full matrix least-squares method to R=0.070. The conformation about the glycosidic bond is syn probably because of the steric hindrance between the sugar moiety and the cyano group at the C(6) position of the base. The sugar puckering is C(4′)-exo, and the orientation of C(5′)-0(5′) bond is gauche-trans.

Chemical & Pharmaceutical Bulletin | 1985

Synthesis of 6, 2'-Methano-cyclouridine, a Uridine Fixed in High-Anti Conformation (Nucleosides and Nucleotides. LX)

Tomoharu Sano; Satoshi Shuto; Hideo Inoue; Tohru Ueda

Chemical & Pharmaceutical Bulletin | 1988

Synthesis of 6, 3'-Methanocytidine, 6, 3'-Methanouridine, and Their 2'-Deoxyribonucleosides (Nucleosides and Nucleotides. LXXVII)

Yuichi Yoshimura; Tomoharu Sano; Akira Matsuda; Tohru Ueda

Chemical & Pharmaceutical Bulletin | 1986

A FACILE SYNTHESIS OF 6, 3'-METHANO-URIDINE AND-CYTIDINE FROM A 3-KETOSUGAR : NUCLEOSIDES AND NUCLEOTIDES LXVIII

Tomoharu Sano; Tohru Ueda

Chemical & Pharmaceutical Bulletin | 1985

Nucleosides and nucleotides. LIX: Synthesis of 2'-deoxy-6,2'-methano-cyclouridine

Tomoharu Sano; Hideo Inoue; Tohru Ueda

Chemical & Pharmaceutical Bulletin | 1985

Nucleosides and Nucleotides. LIV. Synthesis of 6, 6'-Cyclo-5', 6'-dideoxyhexofuranosyluracils via Radical Cyclization of a 6-Cyanouridine

Tomoharu Sano; Hideo Inoue; Tohru Ueda

Chemical & Pharmaceutical Bulletin | 1988

Nucleosides and nucleotides. LXXVII: Synthesis of 6,3'-methanocytidine, 6,3'-methanouridine, and their 2'-deoxyribonucleosides

Yuichi Yoshimura; Tomoharu Sano; Akira Matsuda; T. Ueda

ChemInform | 1986

Synthesis of 2′-Deoxy-6,2′-methano-cyclouridine.

Tomoharu Sano; Hideo Inoue; Tohru Ueda

ChemInform | 1986

Synthesis of 6,2′-Methano-cyclouridine, a Uridine Fixed in High-Anti Conformation.

Tomoharu Sano; Satoshi Shuto; Hideo Inoue; Tohru Ueda

ChemInform | 1984

Synthesis of 6,2′-Methylene-cyclouridines.

Hideo Inoue; Tomoharu Sano; Satoshi Shuto; Tohru Ueda

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Tohru Ueda

Hokkaido University

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Hideo Inoue

Hokkaido University

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Satoshi Shuto

Hokkaido University

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Akira Matsuda

Juntendo University

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Yuichi Yoshimura

Hokkaido University

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Ken-ichi Tomita

Osaka University

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Nobuo Okabe

Osaka University

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Yukari Kobayashi

Osaka University

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Yuriko Yamagata

Kumamoto University

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T. Ueda

Montefiore Medical Center

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