Tomokazu Mizuno

Characteristics of Helicobacter pylori-Induced Gastritis and the Effect of H. pylori Eradication in Patients with Chronic Idiopathic Thrombocytopenic Purpura

Background.  The association between Helicobacter pylori infection and idiopathic thrombocytopenic purpura (ITP) has been reported widely. We investigated the prevalence of H. pylori infection, its virulence profile and the effectiveness of its eradication in patients with ITP.

Catalytic enantioselective alkyl and aryl addition to aldehydes and ketones with organozinc reagents derived from alkyl Grignard reagents or arylboronic acids

A highly practical, catalytic enantioselective alkyl and aryl addition to aldehydes and ketones with organozinc reagents, which were prepared in situ from commercially available Grignard reagents or arylboronic acids, was developed. A chiral phosphoramide ligand was essential for promoting the addition reactions in high yields with high enantioselectivities.

Changes in biochemical parameters related to atherosclerosis after Helicobacter pylori eradication: HELICOBACTER PYLORI ERADICATION AND ATHEROSCLEROSIS

Recent evidence suggests that Helicobacter pylori infection is involved in the pathogenesis of extra‐gastrointestinal diseases such as coronary heart disease.

Long-term follow-up after eradication of Helicobacter pylori with omeprazole, clarithromycin, and tinidazole (OCT regimen) in a Japanese population

Background.  The long‐term benefit of Helicobacter pylori eradication treatment that includes metronidazole on peptic ulcer disease in Japan is unclear. We investigated the rate of H. pylori re‐infection and ulcer relapse after H. pylori eradication.