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Dive into the research topics where Tomoko Nakajima is active.

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Featured researches published by Tomoko Nakajima.


Synthetic Communications | 1984

Ketene-S,N-acetals as Synthetic Intermediates for Heterocycles. A New Synthesis of 4-Arylaminopyrimidines

Hiroki Takahata; Tomoko Nakajima; Katsuhide Matoba; Takao Yamazaki

Abstract Reaction of β-aminothiocarbonyl-α-methylthioenamines (3a-d) derived from ketene-S, N-acetal (1) with benzamidine and guanidine gave 4-arylamino-pyrimidines (4a-d and 5a-d), respectively.


Synthetic Communications | 1984

Ketene-S, N-Acetals As Synthetic Intermediates of Heterocycles. New Synthesis of Uracil and Barbituric Acid Derivatives

Hiroki Takahata; Tomoko Nakajima; Takao Yamazaki

Abstract The importance of enamines for organic synthesis is well documented.1 Ketene-S,N-acetals2 derived from tertiary thioamides are α-alkylthiosubstituted enamines and expected to work as the synthetic equivalent of an enolate anion3. We have been interested in exploring their synthetic utility as the intermediates of heterocycles.4


Chemical & Pharmaceutical Bulletin | 1985

Ketene-S, N-acetals as Synthetic Intermediates for Heterocycles. Reaction of Ketene-S, N-acetals with Aryl Isocyanates

Hiroki Takahata; Tomoko Nakajima; Masaharu Nakano; Akira Tomiguchi; Takao Yamazaki


Chemical & Pharmaceutical Bulletin | 1984

Ketene-S,N-acetals as synthetic intermediates for heterocycles. A novel synthesis of polyfunctionalized pyridine-2-thiones.

Hiroki Takahata; Tomoko Nakajima; Takao Yamazaki


Synthesis | 1983

Activated Lactams: New Syntheses of Azacycloalka[2,3-d]pyrimidine and -[2,3-c]pyrazole Derivatives

Hiroki Takahata; Tomoko Nakajima; Takao Yamazaki


Synthesis | 1984

A new synthesis of 1-substituted 7-methyl-2-oxo-4-thioxo-1,2,3,4,5,6-hexahydro-7H-pyrrolo-and 8-methyl-2-oxo-4-thioxo-1,2,3,4,5,6,7,8-octahydropyrido[2,3-d]pyrimidines

Hiroki Takahata; Tomoko Nakajima; Takao Yamazaki


Chemical & Pharmaceutical Bulletin | 1987

Ketene-S, N-acetals as Synthetic Intermediates for Heterocycles. New Synthesis of Multisubstituted Pyridine-2-thiones

Hiroki Takahata; Eng Chi Wang; Tomoko Nakajima; Takao Yamazaki


ChemInform | 1986

Synthesis of Nitrogen- and Oxygen-Heterocycles Using Ketene-S,N- acetals.

Hiroki Takahata; Keiko Moriyama; Akira Anazawa; Tomoko Nakajima; Yasunori Banba; Takao Yamazaki


ChemInform | 1986

Ketene-S,N-acetals as Synthetic Intermediates for Heterocycles.

Hiroki Takahata; Tomoko Nakajima; Masaharu Nakano; Akira Tomiguchi; Takao Yamazaki


ChemInform | 1985

KETENE-S,N-ACETALS AS SYNTHETIC INTERMEDIATES FOR HETEROCYCLES. A NEW SYNTHESIS OF 4-(ARYLAMINO)PYRIMIDINES

Hiroki Takahata; Tomoko Nakajima; Katsuhide Matoba; Takao Yamazaki

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Hiroki Takahata

Tohoku Pharmaceutical University

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