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Dive into the research topics where Tomoyasu Ohno is active.

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Featured researches published by Tomoyasu Ohno.


Tetrahedron | 1991

New methods and reagents in organic synthesis. 92. A stereoselective synthesis of tilivalline and its analogs.

Shigehiro Mori; Tomoyasu Ohno; Hiroshi Harada; Toyohiko Aoyama; Takayuki Shioiri

Tilivalline (1a), a metabolite from Klebsiella pneumoniae var. oxytoca, and its derivatives 1 have been efficiently and stereoselectively synthesized from diphenyl phosphorazidate, the 2-oxazoline 2, the L-proline derivatives 5, and indole; the key step is a Mannich type intramolecular cyclization accompanied with completely stereoselective introduction of indole. Furthermore, 11-substituted 5H- pyrrolo[2,1-c][1,4]benzodiazepin-5-ones (16) have been also synthesized from the acetal amide 9a and various nucleophiles by the use of this new Mannich type cyclization.


Organic Process Research & Development | 2003

There's No Industrial Biocatalyst Like Hydrolase: Development of Scalable Enantioselective Processes Using Hydrolytic Enzymes1

Yasuo Chikusa; Yoshihiro Hirayama; Masaya Ikunaka; Toru Inoue; Shunji Kamiyama; Masafumi Moriwaki; Yukifumi Nishimoto; Fumiki Nomoto; Kazuo Ogawa; Tomoyasu Ohno; Koutaro Otsuka; Akiko K. Sakota; Naoki Shirasaka; and Atsuko Uzura; Kensaku Uzura


Archive | 1993

Oxazolidine derivatives and pharmaceutically acceptable salts thereof

Shingo Yano; Tomoyasu Ohno; Kazuo Ogawa; Haruo Yamada; Tetsuhiko Shirasaka; Shinichi Watanabe


Archive | 1993

Oxazolidine derivative and pharmaceutically acceptable salt thereof

Shingo Yano; Tomoyasu Ohno; Kazuo Ogawa; Haruo Yamada; Tetsuhiko Shirasaka; Shinichi Watanabe


Archiv Der Pharmazie | 2005

Synthesis and Structure‐Activity Relationship of 4‐Substituted Benzoic Acids and their Inhibitory Effect on the Biosynthesis of Fatty Acids and Sterols

Tomoyasu Ohno; Kazuo Ogawa; Shingo Yano; Masakazu Fukushima; Norihiko Suzuki; Tetsuji Asao


Chemical & Pharmaceutical Bulletin | 1984

New methods and reagents in organic synthesis. 43. A new synthesis of tert-butyl peroxycarboxylates using diethyl phosphorocyanidate (DEPC).

Yasumasa Hamada; Akira Mizuno; Tomoyasu Ohno; Takayuki Shioiri


Chemical & Pharmaceutical Bulletin | 1999

Synthesis of the Optical Isomers of 4-[1-(4-tert-Butylphenyl)-2-oxo-pyrrolidine-4-yl]methyloxybenzoic Acid (S-2) and Their Biological Evaluation as Antilipidemic Agent

Tomoyasu Ohno; Shingo Yano; Haruo Yamada; Tetsuhiko Shirasaka; Akira Yamamoto; Kimiko Kobayashi; Kazuo Ogawa


Archive | 1993

Optically Active 1-Phenylpyrrolidone Derivative, Intermediate for Producing the Same, and Process for Producing Both

Shingo Yano; Tomoyasu Ohno; Kazuo Aza Takahata Aihata Ishii-Cho Ogawa; Tetsuhiko Shirasaka


Archive | 1993

1-phenylpyrrolidone derivatives having optical activity, intermediate for the preparation thereof and processes for their preparation

Shingo Yano; Tomoyasu Ohno; Kazuo Ogawa; Tetsuhiko Shirasaka


Archive | 1993

OPTICALLY ACTIVE 1-PHENYLPYRROLIDONE DERIVATIVE AND PREPARATION THEREOF

Kazuo Aza Takahata Aihata Ishii-Cho Ogawa; Tomoyasu Ohno; Tetsuhiko Shirasaka; Shingo Yano

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Akira Yamamoto

Kyoto Pharmaceutical University

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Kimiko Kobayashi

Tokyo Institute of Technology

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Masaya Ikunaka

Yasuda Women's University

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