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Dive into the research topics where Toni-Jo Poel is active.

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Featured researches published by Toni-Jo Poel.


Tetrahedron Letters | 2000

Stereodivergent synthesis of sulfoxide-containing oxazolidinone antibiotics

James R. Gage; William R. Perrault; Toni-Jo Poel; Richard C. Thomas

Abstract Carbamate 5 was prepared under mild conditions via a novel metal–halogen exchange procedure without competing benzyne formation. Selection of an appropriate oxidation/reduction sequence afforded access to either the cis - or trans -1-oxo-4-aryltetrahydrothiopyran system, important intermediates in the synthesis of a new class of oxazolidinone antibiotics.


Archive | 1998

Oxazolidinone antibacterial agents having a thiocarbonyl functionality

Jackson B. Hester; Eldon G. Nidy; Salvatore Charles Perricone; Toni-Jo Poel


Archive | 1996

Phenyloxazolidinones having a c-c bond to 4-8 membered heterocyclic rings

Douglas K. Hutchinson; Michael D. Ennis; Robert Louis Hoffman; Richard C. Thomas; Toni-Jo Poel; Michael R. Barbachyn; Steven J. Brickner; David John Anderson


Archive | 2003

N-aryl-2-oxazolidinone-5-carboxamides and their derivates and their use as antibacterials

Richard C. Thomas; Toni-Jo Poel; Michael R. Barbachyn; Mikhail F. Gordeev; Gary W. Luehr; Adam Renslo; Upinder Singh


Archive | 1995

Alkyl substituted piperadinyl and piperazinyl anti-aids compounds

Donna L. Romero; Richard C. Thomas; Paul D. May; Toni-Jo Poel


Journal of Medicinal Chemistry | 2007

Antibacterial oxazolidinones possessing a novel C-5 side chain. (5R)-trans-3-[3-Fluoro-4- (1-oxotetrahydrothiopyran-4-yl)phenyl]-2- oxooxazolidine-5-carboxylic acid amide (PF-00422602), a new lead compound.

Toni-Jo Poel; Richard C. Thomas; Wade J. Adams; Paul A. Aristoff; Michael R. Barbachyn; Frederick E. Boyer; Joan K. Brieland; Roger J. Brideau; Joanne Brodfuehrer; Alan P. Brown; Allison L. Choy; Michael R. Dermyer; Michael Dority; Charles W. Ford; Robert C. Gadwood; Debra Hanna; Cai Hongliang; Michael D. Huband; Christopher Huber; Rose Kelly; Ji Young Kim; Joseph P. Martin; Paul J. Pagano; Daniel Ross; Laura Skerlos; Mark C. Sulavik; Tong Zhu; Gary E. Zurenko; J. V. N. Vara Prasad


Archive | 1998

S-oxide and S,S-dioxide tetrahydrothiopyran phenyloxazolidinones

Toni-Jo Poel; Joseph P. Martin; Michael R. Barbachyn


Archive | 2003

N-aryl-2-oxazolidinone-5-carboxamides and their derivatives

Richard C. Thomas; Toni-Jo Poel; Michael R. Barbachyn; Mikhail F. Gordeev; Gary W. Luehr; Adam R. Renslo; Upinder Singh; Vara Prasad Venkata Nagendra Josyula


Archive | 2004

Indolone oxazolidinones and derivatives thereof

Toni-Jo Poel


Archive | 2001

Oxazolidinones having a benzannulated 6-or 7-membered heterocycle as antibacterial agents

Paul D. Johnson; Paul Adrian Aristoff; Toni-Jo Poel; Lisa M. Thomasco

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