Toshiaki Ogawara

Liposarcoma of the Tongue: Case Report and Literature Update:

Liposarcoma is an exceedingly rare tumor in the oral cavity. We report a case of a 70-year-old man with liposarcoma that presented as a lump on the tongue. The excised tumor was diagnosed as a well-differentiated lipoma-like liposarcoma. The majority of cases of well-differentiated liposarcoma follow a relatively benign course, but the disease has a high recurrence rate. It appears that accurate clinical and histopathologic diagnosis of this lesion is difficult. The prognosis seems to depend on the histologic type, size, and location of the lesion. Wide surgical excision is important for successful management of these liposarcomas.

Necrosis of the tongue after transient ischemic attack

We report an unusual case of necrosis of the tongue after transient ischemic attack in a 67-year-old man. Angiography revealed occlusion of the right external carotid artery at the bifurcation of the common carotid artery. Debridement of the wound and removal of the necrotic tissue resulted in good healing.

Evaluation of facial palsy by Moiré topography.

To evalute facial nerve function, several visual assessment methods have proposed by May, Yanagihara, Stennert, House, Brackman, among others, and the score method is widely accepted as a simple and useful method for examination to evaluate roughly the degree of facial palsy. However, it is difficult to capture fine changes with the score method when precise evaluation is required, and it is limited as a form of objective and reporducible assessment. Therefore, it is not a very suitable method to follow up the process of the recovery in facial nerve palsy.

Vibration Analysis of the Human Skull and Auditory Ossicles by Holographic Interferometry

Holographic interferometry was applied to medical investigation regarding the vibration analysis of some parts of the human sound conducting system.

Vibration analysis of the tympanic membrane with a ventilation tube and a perforation by holography

For severe otitis media with effusion, insertion of a ventilation tube is performed for the purpose of ventilation of the middle ear cavity and normalization of the eustachian tubular function and middle ear mucosa. The ventilation tube is left in place for as long as several months or even a few years. However, the influence of the indwelling tube on vibration of the tympanic membrane is unknown. Therefore, the authors observed the influence by means of time-averaged holography using human tympanic membranes. The following results were obtained. After insertion of a ventilation tube, vibration pattern of the tympanic membrane was not obviously changed, but the vibration amplitude of the tympanic membrane was decreased, especially at 500 Hz. Generally speaking, the change caused by insertion of a ventilation tube was very small. Also, the vibration pattern of perforated tympanic membrane was not changed, but the vibration amplitude of perforated tympanic membrane was decreased at the low frequency area.

Leriche operation for parotid gland pathology.

Departments of Otolaryngology, Head and Neck Surgery, Okayama, Ogawara ENT Clinic, Okayama, Eki-mae ENT Clinic, Department of Otolaryngology, Head and Neck Surgery, Okayama, Okayama Saiseikai General Hospital, Okayama, Okayama Medical Center, Okayama, Himeji Red Cross Hospital, Hyogo, Japan and Pathology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama

The Alteration of Penicillin-Binding Proteins (PBPs) in Drug-resistant Streptococcus pneumoniae Isolated from Acute Otitis Media

Streptococcus pneumoniae is the micro-organism most frequently isolated from acute otitis media (AOM). Recently, drug-resistant or insensitive strains have been prevalent among pneumococcal AOM cases and were reportedly associated with persistent or recurrent otitis media. The purpose of this study was to examine the alterations of penicillin-binding proteins (PBPs) in Streptococcus pneumoniae isolated from AOM. The PBP samples from 21 clinically isolated strains were examined by 14C-penicillin binding assay and also by adding CCL and CDTR as competitors of 14C-penicillin. Reduced signals in PBP1A and PBP2X/2A were typically observed with the penicillin-resistant Streptococcus pneumoniae samples, while widely different PBP profiles were obtained in each strain of penicillin-insensitive Streptococcus pneumoniae. The competitive binding assay with penicillin-insensitive strains revealed the reduced affinity of CCL to PBPs in comparison with that of CDTR. The results of the penicillin-binding assay were consistent with the results from minimal inhibitory concentration analysis, and its potential usefulness for the prediction of drug resistance was demonstrated.

Development Of Pulse Holo-Camera For Observation Of Vibration Of Human Eardrum

For the purpose of observing the vibration of the human tympanic membrane clinically, a holocamera was test designed and manufactured. At the stage of test design, an experiment revealed the deterioration of laser light in its coherency when it came out through the optical fiber. As the method of improving the deteriorated coherency, two laser beams both of which were passed through the optical fiber bundle, were used for the illumination beam as well as the reference beall under a certain condition. This procedure made possible to manufacture a pulsed holo-camera well suitable for the clinical use