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Toshifumi Asaka

Taisho Pharmaceutical Co.

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Publication

Featured researches published by Toshifumi Asaka.

Heterocycles | 1993

Chemical Modification of Erythromycins. X. Removal of Benzyloxycarbonyl and 2-Chlorobenzyl Groups of Erythromycin Derivatives by Use of Catalytic Transfer Hydrogenation

Yoshiaki Watanabe; Masato Kashimura; Toshifumi Asaka; Takashi Adachi; Shigeo Morimoto

The benzyloxycarbonyl and the 2-chlorobenzyl groups of ethythromycin derivatives were easily removed by catalytic transfer hydrogenation (CTH). Their deprotection reaction was dependent on both the hydrogen donor and the solvent for use. Application of CTH to removal of the protective groups is discussed

Archive | 1997

Erythromycin a derivatives

Shigeo Morimoto; Takashi Adachi; Tohru Matsunaga; Masato Kashimura; Toshifumi Asaka; Yoshiaki Watanabe; Kaoru Sota; Kazuto Sekiuchi

Archive | 1985

6-o-methylerythromycin a derivative

Shigeo Morimoto; Takashi Adachi; Toshifumi Asaka; Yoshiaki Watanabe; Kaoru Sota

Archive | 1993

5-o-desosaminylerythronolide a derivative

Toshifumi Asaka; Masato Kashimura; Yoko Misawa; Shigeo Morimoto; Katsuo Hatayama

Archive | 1985

Method for selective methylation of erythromycin a derivatives

Yoshiaki Watanabe; Shigeo Morimoto; Masami Goi; Morihiro Mitsukuchi; Takashi Adachi; Jozi Nakagami; Toshifumi Asaka; Tadashi Eguchi; Kaoru Sota

Journal of Medicinal Chemistry | 2003

Synthesis and antibacterial activity of a novel series of acylides: 3-O-(3-pyridyl)acetylerythromycin A derivatives.

Tetsuya Tanikawa; Toshifumi Asaka; Masato Kashimura; Keiko Suzuki; Hiroyuki Sugiyama; Masakazu Sato; Kazuya Kameo; Shigeo Morimoto; Atsushi Nishida

Journal of Medicinal Chemistry | 2001

Synthesis and Antibacterial Activity of Acylides (3-O-Acyl-erythromycin Derivatives): A Novel Class of Macrolide Antibiotics

Tetsuya Tanikawa; Toshifumi Asaka; Masato Kashimura; Yoko Misawa; Keiko Suzuki; Masakazu Sato; Kazuya Kameo; Shigeo Morimoto; Atsushi Nishida

Archive | 1991

6-0-methylerythromycin A derivatives

Masato Kashimura; Toshifumi Asaka; Shigeo Morimoto; Katsuo Hatayama

The Journal of Antibiotics | 1993

Chemical modification of erythromycins. IX: Selective methylation at the C-6 hydroxyl group of erythromycin A oxime derivatives and preparation of clarithromycin

Yoshiaki Watanabe; Shigeo Morimoto; Takashi Adachi; Masato Kashimura; Toshifumi Asaka

Archive | 1987

Erythromycin a derivatives and method for the preparation of the same

Shigeo Morimoto; Takashi Adachi; Masato Kashimura; Toshifumi Asaka; Kaoru Sota; Yoshiaki Watanabe; Kazuto Sekiuchi; Tohru Matsunaga

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Masato Kashimura

Josai University

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Shigeo Morimoto

Taisho Pharmaceutical Co.

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Yoshiaki Watanabe

Taisho Pharmaceutical Co.

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Katsuo Hatayama

Taisho Pharmaceutical Co.

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Yoko Misawa

Taisho Pharmaceutical Co.

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Takashi Adachi

Kobe University

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Kaoru Sota

Taisho Pharmaceutical Co.

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Tetsuya Tanikawa

Taisho Pharmaceutical Co.

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Chihiro Yokoo

Taisho Pharmaceutical Co.

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Jiro Sawada

Taisho Pharmaceutical Co.

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