Toshiyuki Takeda
Takeda Pharmaceutical Company
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Publication
Featured researches published by Toshiyuki Takeda.
Heterocycles | 2004
Hiroaki Inagaki; Toshiyuki Takeda; Rie N. Miyauchi; Katsuhiro Kawakami; Hisashi Takahashi; Makoto Takemura
A practical route was developed for synthesizing the C-7 substituent of DQ-113 (6, 5-amino-7-[(3S,4R)-4-(1-aminocycloprop-1-yl)-3-fluoropyrrolidin-1-yl]-6-fluoro-1-[(1R,2S)-2-fluorocyclopropan-1-yl]-1,4-dihydro-8-methyl-4-oxoquinolin-3-carboxylic acid), a new quinolone antibacterial agent for serious infections caused by Gram-positive pathogens. The key step was the intramolecular Homer-Wadsworth-Emmons reaction. In addition, the yield of the final aromatic nucleophilic substitution reaction was improved.
Archive | 1999
Makoto Takemura; Hisashi Takahashi; Rie Miyauchi; Toshiyuki Takeda; Isao Hayakawa
Archive | 2000
Makoto Takemura; Hisashi Takahashi; Katsuhiro Kawakami; Toshiyuki Takeda; Rie Miyauchi
Archive | 1998
Makoto Edogawa-ku Takemura; Hisashi Edogawa-ku Takahashi; Hitoshi Edogawa-ku Ohki; Kenichi Kimura; Rie N. Miyauchi; Toshiyuki Takeda
Arkivoc | 2003
Hiroaki Inagaki; Kazuyuki Sugita; Rie N. Miyauchi; Satoru Miyauchi; Toshiyuki Takeda; Masao Itoh; Hisashi Takahashi; Makoto Takemura
Archive | 2005
Makoto Takemura; Hisashi Takahashi; Rie Miyauchi; Toshiyuki Takeda; Isao Hayakawa
Archive | 2000
Makoto Takemura; Hisashi Takahashi; Katsuhiro Kawakami; Toshiyuki Takeda; Rie Miyauchi
Archive | 1999
Isao Hayakawa; Rie Miyauchi; Hisashi Takahashi; Toshiyuki Takeda; Makoto Takemura
Archive | 1999
Isao Daiichi Pharm. Co. Ltd. Hayakawa; Rie Miyauchi; Hisashi Takahashi; Toshiyuki Takeda; Makoto Daiichi Pharm. Co. Ltd. Takemura
Archive | 1999
Makoto Takemura; Hisashi Takahashi; Rie Miyauchi; Toshiyuki Takeda; Isao Hayakawa
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National Institute of Advanced Industrial Science and Technology
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