Toto Saktioto

Gold nanoparticle trapping and delivery for therapeutic applications

A new optical trapping design to transport gold nanoparticles using a PANDA ring resonator system is proposed. Intense optical fields in the form of dark solitons controlled by Gaussian pulses are used to trap and transport nanoscopic volumes of matter to the desired destination via an optical waveguide. Theoretically, the gradient and scattering forces are responsible for this trapping phenomenon, where in practice such systems can be fabricated and a thin-film device formed on the specific artificial medical materials, for instance, an artificial bone. The dynamic behavior of the tweezers can be tuned by controlling the optical pulse input power and parameters of the ring resonator system. Different trap sizes can be generated to trap different gold nanoparticles sizes, which is useful for gold nanoparticle therapy. In this paper, we have shown the utility of gold nanoparticle trapping and delivery for therapy, which may be useful for cosmetic therapy and related applications.

Generation of THz frequency using PANDA ring resonator for THz imaging

In this study, we have generated terahertz (THz) frequency by a novel design of microring resonators for medical applications. The dense wavelength-division multiplexing can be generated and obtained by using a Gaussian pulse propagating within a modified PANDA ring resonator and an add/drop filter system. Our results show that the THz frequency region can be obtained between 40–50 THz. This area of frequency provides a reliable frequency band for THz pulsed imaging.

Ultra-short Laser Pulse Generated by a Microring Resonator System for Cancer Cell Treatment

Abstract A microring resonator (MRRs) system incorporated with a add/drop filter is proposed in which ultra-short single, multi-temporal, and spatial optical soliton pulses are simulated and used to kill abnormal cells, tumors, and cancer. Chaotic signals are generated by a bright soliton pulse within a nonlinear MRRs system. Gold nanoparticles and ultra-short femtosecond/picosecond laser pulses’ interaction holds great interest in laser nanomedicine. By using appropriate soliton input power and MRRs parameters, desired spatial and temporal signals can be generated over the spectrum. Results show that short temporal and spatial solitons pulse with FWHM = 712 fs and FWHM = 17.5 pm could be generated. The add/drop filter system is used to generate the high-capacity, ultra-short soliton pulses in the range of nanometer/second and picometer/second.

Non Linear Optic in Fiber Bragg Grating

A Fiber Bragg Grating (FBG) is a periodic variation of the refractive index of the core in the fiber optic along the length of the fiber. The principal property of FBGs is that they reflect light in a narrow bandwidth that is centered about the Bragg wavelength, ?B (A. Orthonos and K. Kalli, 1999). FBGs are simple intrinsic devices that are made in the fibre core by imaging an interference pattern through the side of the fibre. They are used as flexible and low cost in-line components to manipulate any part of the optical transmission and reflection spectrum. FBG is formed by the periodic variations of the refractive index in the fiber core. Several techniques have been established to inscribe them with UV-lasers. However, these technologies are limited to photosensitive fiber core material, which are unsuitable for high power applications. Only recently modifications have been demonstrated in a non photosensitive fiber but at the expense of longer exposure times (K. W. Chow et al., 2008). FBGs have all the advantages of an optical fibre, such as electrically passive operation, lightweight, high sensitivity with also unique features for self-referencing and multiplexing capabilities. This gives them a distinct edge over conventional devices (Nahar Singh et. al, 2006, Govind P. Agrawal 2002).

Modification of Coupling Power Parameters for High Accuracy Coupling Ratio of Weakly Coupled Fiber

The directional fiber couplers consist of multi fibers joint have been successfully fabricated by heating of torch flame at atmospheric pressure and pulling the fiber coupling region mechanically at micro scale. Good performance of the coupling coefficient and the coupling ratio was obtained by setting the initial parameter of coupler machine such as the coupling coefficient, pulling speed, pulling length, coupling ratio, Hidrogen gas flow and pressure and heating temperature during process. The Coupling coefficient of 3-dB fused directional fiber coupler was determined based on perturbation method and coupling mode. A good agreement between theoretical purposed and empirical coupling coefficient from experimental result was reported. The coupling coefficient between the waveguides is significantly induced by the distance of axial separation between parallel fibers and geometrical coupling region. It is exponentially decreases by increasing separation between fibers. However, by controlling the coupling coefficient, the desired coupling ratio can be easily attained.

Numerical simulation of spherical plasma focus device using Lee model

Summary form only given. The plasma focus device is a potential source for multi-radiation emission. Lee model has been developed with a complete description of the plasma focus dynamics to simulate the plasma motion in both the axial and radial phase. The code couples the electrical circuit with plasma focus (PF) dynamics, thermodynamics and radiation. Spherical plasma focus device is a special case between Mather and Filippov configurations. Spherical electrodes made the chamber design more compact when compare to Mather-type and Filippov-type. In this study, numerical simulation for spherical plasma focus device using Lee model has been performed to test the universality of Lee model. Experimental results from a spherical plasma focus device is compared with numerical simulations results in terms of neutron yield and X-ray radiation for different gases and at different pressure.

Theoretical improvement of coupling parameters directional fiber coupler using Bessel function

We have investigated the optimum parameter to fabricate multi fiber of silica material for directional coupler based on fusion and elongation techniques. Coupling coefficient between the fibers was derived by using Bessel function. 476 Dedi Irawan et al. However, the fusion temperature was experimentally determined as function of elongation speed. Good performance of multi fiber coupler has been obtained for fabrication parameters of fusion temperature and elongation speed of 1350 C and 125 μm/s respectively. The proposed coupling coefficient shows a better accuracy with empirical one for various coupling length. It is exponentially increased by reducing the distance between fibers. Finally, the microscopic analysis of coupling region deformation has shown that the silica material was well dispersed and distributed.

Multiport Single Mode Fiber Coupler Technique for Mechanical Microactuator to Damped Blood Flow

We have proposed and optimize the optical parameters to fabricate multiport fiber coupler to support microactuator device based on fusion and elongation techniques. The coupling coefficient between the fibers was derived by using Hankel and Bessel function. However, the fusion technique was experimentally described as a function of elongation speed. Good performance of multi fiber coupler has been obtained for fabrication parameters of fusion temperature and elongation speed of 1350 oC and 125 μm/s respectively. The proposed coupling coefficient shows a better accuracy with empirical one for various coupling length. The coupling coefficient is exponentially increased by reducing the distance between fibers. Finally, the microscopic analysis of coupling region deformation has shown that the silica material was well dispersed and distributed.

Acne vulgarism treatment using ultra-short laser pulse generated by micro- and nano-ring resonator system

Abstract Acne vulgaris is adebilitating dermatologic disease, and is conventionally treated by laser therapy using a microring resonator system. An evolving understanding of laser-tissue interactions involving Propioni bacterium acneproducing porphyrins, and the development of lasers to target the sebaceous glands, has led to the development of an escalating number of laser light for acne treatment. The results show that the full width at half maximum of the proposed laser pulse of 0.15 nm can be generated using a microring resonator system. The power of the laser is 200 W and the wavelength laser is 1,032 nm, which is proposed as a treatment of acne vulgaris diseases.

Drug trapping and delivery for Alzheimer's diagnosis

Abstract In this investigation, a new design based on a PANDA ring resonator as an optical trapping tool for tangle protein, molecular motor storage, and delivery is proposed. The optical vortices are generated and the trapping mechanism is controlled in the same way as the conventional optical tweezers. The trapping force is produced by a combination of the gradient field and scattering photons. The required molecular volume is trapped and moved dynamically within the molecular network. The tangle protein and molecular motor can be transported and delivered to the required destinations for Alzheimers diagnosis by molecular buffer and bus network.