Tsukasa Tsuda

Cancer disclosure in Japan: Historical comparisons, current practices

Although Japanese physicians historically have not disclosed cancer diagnoses to patients, pressures upon physicians to disclose have increased in recent years. We questioned physicians practicing at a private medical hospital in rural Japan about their current approach to cancer disclosure. We compared their responses with responses of physicians in a 1991 study conducted in Japan, and two studies conducted in the United States, in 1961 and in 1977. Seventy-seven clinically active physicians with experience treating cancer patients responded (73% response rate). Forty percent of respondents reported usually telling patients of a cancer diagnosis, over three times more than the 13% who reported such a policy in Japan in 1991. Physicians were significantly more likely (P < 0.001) to make exceptions than physicians in the previous Japanese study, and physicians in the previous U.S. studies. Respondents reported considering more factors in deciding whether to tell than participants in the 1977 U.S. study. Factors predicting an increased probability of disclosure included age (in a hyperbolic relationship), improved prognosis, breast or cervical cancer, and social status and religion (by a minority of respondents). Increase in a substitute decision makers age was predictive for physicians not to involve the person in decision-making. Most respondents reported their disclosure policy is based on clinical experience. More respondents indicated a likelihood of changing in the future than respondents in the previous U.S. studies. These data suggest Japanese physicians are moving away from a rigid policy of nondisclosure to a policy of selective disclosure, but they have not adopted universal cancer disclosure as practiced in many Western countries. Since young age and advanced age predicted self-reports of not disclosing cancer diagnoses, these data raise the question of whether nondisclosure by age groups represents age discrimination or compassionate medical care tailored to individual patient needs.

Thallium-201 imaging with color display computer system in old myocardial infarction

In 13 patients with old myocardial infarction diagnosed with use of the electrocardiogram, coronary angiogram and left ventriculogram and in 11 patients without infarction, thallium-201 imaging with a color display computer system was carried out. In the group without infarction the average ratio of activities in two regions of interest within the myocardial wall, excluding the apex, was 1.14 (1.08 to 1.23). In the group with infarction the average ratio of noninfarcted to infarcted areas was 1.44 (1.23 to 1.78). Objective detection of infarction was possible in 12 patients (92 percent) in the group with infarction. In two patients, the earlier electrocardiographic pattern of infarction had resolved by the time of imaging. These results suggest that the sensitivity of thallium-201 imaging in the diagnosis of old myocardial infarction may be greatly enhanced by objective and quantitative analysis using a color display computer system.

Case Report: Intraglomerular Metastasis With Neoplastic Cell Interposition

A case is described of an 88-year-old man with lung cancer, nephrotic syndrome, and renal dysfunction who died suddenly of an acute myocardial infarction and whose autopsy revealed many adenocarcinoma cells stacked within glomerular capillary lumina of his kidney, entering into basement membrane zones (ie, neoplastic cell interposition). In addition, glomeruli showed a lobular transformation, doubling of glomerular basement membrane, and electron dense deposits along the glomerular basement membrane. These changes were similar to those of membraneoproliferative glomerulonephritis. The association of intraglomerular metastasis and membranoproliferative glomerulonephritis-like lesions led the authors to speculate that the latter glomerular change might have provided an attractive opportunity for circulating tumor cells to be trapped and grow within the glomerular lumina. This mode of metastasis has not been well-recognized. The authors describe the experience, review the literature, and discuss its possible pathogenesis.

The cultural context of teaching and learning sexual health care examinations in Japan: a mixed methods case study assessing the use of standardized patient instructors among Japanese family physician trainees of the Shizuoka Family Medicine Program.

BackgroundIn contrast to many western nations where family medicine is a cornerstone of the primary care workforce, in Japan the specialty is still developing. A number of services within the bailiwick of family medicine have yet to be fully incorporated into Japanese family medicine training programs, especially those associated with sexual health. This gap constitutes a lost opportunity for addressing sexual health-related conditions, including cancer prevention, diagnosis, and treatment. In this mixed methods case study we investigated the perceived acceptability and impact of a standardized patient instructor (SPI) program that trained Japanese family medicine residents in female breast, pelvic, male genital, and prostate examinations.Case descriptionBuilding on an existing partnership between the University of Michigan, USA, and the Shizuoka Family Medicine Program, Japan, Japanese family medicine residents received SPI-based training in female breast, pelvic, male genital, and prostate examinations at the University of Michigan. A mixed methods case study targeting residents, trainers, and staff was employed using post-training feedback, semi-structured interviews, and web-based questionnaire.Discussion and evaluationResidents’ and SPIs’ perceptions of the training were universally positive, with SPIs observing a positive effect on residents’ knowledge, confidence, and skill. SPIs found specific instruction-related approaches to be particularly helpful, such as the positioning of the interpreter and the timing of interpreter use. SPIs provided an important opportunity for residents to learn about the patient’s perspective and to practice newly learned skills. Respondents noted a general preference for gender concordance when providing gender-specific health care; also noted were too few opportunities to practice skills after returning to Japan. For cultural reasons, both residents and staff deemed it would be difficult to implement a similar SPI-based program within Japan.ConclusionsWhile the SPI program was perceived favorably, without sufficient practice and supervision the skills acquired by residents during the training may not be fully retained. Deep-rooted taboos surrounding gender-specific health care appear to be a significant barrier preventing experimentation with SPI-based sexual health training in Japan. The feasibility of implementing a similar training program within Japan remains uncertain. More research is needed to understand challenges and how they can be overcome.

Noninvasive Evaluation of Diastolic Filling Patterns in Patients with Atrial Fibrillation by Ejection Time and Preceding Cycle Length

Abstract To study the relation between ejection time and preceding cycle length (heart rate), the carotid arterial pulse tracing and electrocardiogram were simultaneously recorded in 104 patients with atrial fibrillation in various conditions. Ejection time was plotted against preceding heart rate in 30 consecutive cardiac cycles in each patient. The correlation coefficient between ejection time and heart rate, and the slope of the regression line derived from the formula, Y = aX + b, were calculated. In patients with mitral stenosis both the correlation coefficient and the slope were highest (− 0.91[− 0.79 ~ 0.98], − 1.89 ± 0.42); in those with congestive cardiomyopathy the coefficient was low (− 0.68[− 0.45 ~ − 0.85]) whereas the slope was high (− 1.32 ± 0.30); both were lowest in patients with constrictive pericarditis (− 0.08[− 0.06 ~ − 0.11], − 0.28 ± 0.07); and the coefficient was low (− 0.64[− 0.25 ~ 0.95]) but the slope was moderate (− 0.77 ± 0.34) in those with an atrial septal defect. After surgical correction, both the correlation coefficient and the slope decreased in patients with mitral stenosis and increased in those with constrictive pericarditis, indicating a postoperative lessening of abnormal diastolic filling patterns. These results suggest that this method may be useful in evaluating the effect on ejection time of pressure-volume changes brought about by diastolic filling. This method would also be of value in clarifying the hemodynamic patterns and effect of surgery in atrial fibrillation of various origins.

Describing the factors that influence the process of making a shared-agenda in Japanese family physician consultations: a qualitative study

BackgroundPatients cannot always share all necessary relevant information with doctors during medical consultations. Regardless, in order to ensure the best quality consultation and care, it is imperative that a doctor clearly understands each patient’s agenda.The purpose of this study was to analyze the process of developing a shared-agenda during family physician consultations in Japan.MethodsWe interviewed 15 first time patients visiting the outpatient clinic of the Department of Family Medicine in the hospital chosen for the investigation, and the 8 family physicians who examined them. In total we observed 16 consultations. We analyzed both patients’ and doctors’ narratives using a modified grounded theory approach.ResultsFor patients, we found four main factors that influenced the process of making a shared-agenda: past medical experiences, undisclosed but relevant information, relationship with the family physician, and the patient’s own explanatory model. In addition, we found five factors that influenced the shared agenda making process for family physicians: understanding the patient’s explanatory model, constructing the patient-doctor relationship, physical examination centered around the patient’s explanatory model, discussion-styled explanation, and self-reflection on action.ConclusionsThe findings suggest that patient satisfaction would be increased if family physicians are proactive in considering these factors with respect to both the patient’s agenda, and their own.

Utility of self-competency ratings during residency training in family medicine education-emerging countries: findings from Japan

BackgroundFamily medicine education-emerging countries face challenges in demonstrating a new program’s ability to train residents in womb-to-tomb care and resident ability to provide such care competently. We illustrate the experience of a new Japanese family medicine program with resident self-competency assessments.MethodsIn this longitudinal cross-sectional study, residents completed self-competency assessment surveys online during 2011–2015. Each year of training, residents self-ranked their competence using a 100-point visual analog scale for 142 conditions: acute (30 conditions), chronic (28 conditions) women’s health (eight conditions), and geriatrics/home (12 conditions) care; procedures (38 types); health promotion (21 conditions).ResultsTwenty residents (11 women, 9 men) participated. Scores improved annually by training year from baseline to graduation; the mean composite score advanced from 31 to 65%. All subcategories showed improvement. Scores for care involving acute conditions rose from 49 to 75% (26% increase); emergency procedures, 46–65% (19% increase); chronic care, 33–73% (40% increase); women’s health, 16–59% (43% increase); procedural care, 26–56% (30% increase); geriatrics care-procedures, 8–65% (57% increase); health promotion, 21–63% (42% increase). Acute care, chronic care, and health promotion achieved the highest levels. Women’s health care, screenings, and geriatrics experienced the greatest increase. Health promotion gains occurred most dramatically in the final residency year.ConclusionsA resident self-competency assessment provides a simple and practical way to conduct an assessment of skills, to monitor skills over time, to use the data to inform residency program improvement, and to demonstrate the breadth of family medicine training to policymakers, and other stakeholders.