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Dive into the research topics where Tsunehiko Asako is active.

Publication


Featured researches published by Tsunehiko Asako.


Antimicrobial Agents and Chemotherapy | 1974

Selective Phosphorylation of the 5′′-Hydroxy Group of Ribostamycin by a New Enzyme from Pseudomonas aeruginosa

Makoto Kida; Seizi Igarasi; Tetsuya Okutani; Tsunehiko Asako; Kentaro Hiraga; Susumu Mitsuhashi

It was found that the 5′′-hydroxy group of ribostamycin was preferentially phosphorylated by a cell-free extract from Pseudomonas aeruginosa GN 573, a clinical isolate.


Journal of The Chemical Society D: Chemical Communications | 1971

Synthesis of the steroid (±)-17α-ethynyl-17β-hydroxy-13β-allylgon-4-en-3-one

Kouichi Yoshioka; Giichi Goto; Tsunehiko Asako; Kentaro Hiraga; Takuichi Miki

The title compound was synthesized using various methods of protecting the C-13 allyl group from reducing agents.


Journal of The Chemical Society D: Chemical Communications | 1969

Studies on the total synthesis of steroids: the structure of 9,14-epoxy-steroids

Tsunehiko Asako; Kentaro Hiraga; Takuichi Miki

The 9S configuration is assigned to the more stable 9,14α-epoxy-3-methoxy-8,14-seco-oestra-1,3,5(10)-trien-17-one.


Journal of The Chemical Society D: Chemical Communications | 1969

Total synthesis of oestrone via oestriol dimethyl ether

Kentaro Hiraga; Tsunehiko Asako; Takuichi Miki

Cyclization of seco-oestrapentaene (IV) gave an oestriol derivative (V), which was further transformed to oestrone.


Archive | 1967

Total synthesis of 13-hydrocarbon-substituted gonapolyenes

Tsunehiko Asako; Kentaro Hiraga; Takuichi Miki


Chemical & Pharmaceutical Bulletin | 1986

Syntheses of Medium-Sized Heterocycles Using an Intramolecular Michael Reaction

Yutaka Masuoka; Tsunehiko Asako; Giichi Goto; Shunsaku Noguchi


Journal of the American Chemical Society | 1977

Conversion of aminoglycosidic antibiotics: Novel and efficient approaches to 3'-deoxyaminoglycosides via 3'-phosphoryl esters.

Tetsuya Okutani; Tsunehiko Asako; Kouichi Yoshioka; Kentaro Hiraga; Makoto Kida


Chemical & Pharmaceutical Bulletin | 1965

An Improved Synthesis of Estrogens.

Takuichi Miki; Kentaro Hiraga; Tsunehiko Asako


Archive | 1973

Dehydroxylation of aminosugars

Kentaro Hiraga; Tetsuya Okutani; Kouichi Yoshioka; Tsunehiko Asako


Chemical & Pharmaceutical Bulletin | 1973

An Improved Synthesis of optically Active Steroids

Tsunehiko Asako; Kentaro Hiraga; Takuichi Miki

Collaboration


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Takuichi Miki

Takeda Pharmaceutical Company

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Kouichi Yoshioka

Takeda Pharmaceutical Company

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Hirotomo Masuya

Takeda Pharmaceutical Company

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Michio Masuoka

Takeda Pharmaceutical Company

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Tetsuya Okutani

Takeda Pharmaceutical Company

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Toru Yui

Takeda Pharmaceutical Company

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Giichi Goto

Takeda Pharmaceutical Company

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Makoto Kida

Takeda Pharmaceutical Company

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Tadatsugu Harukawa

Takeda Pharmaceutical Company

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