Tsuyoshi Fukudome
Kagoshima University
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Featured researches published by Tsuyoshi Fukudome.
Journal of Cardiology | 2009
Takashi Kihara; Masaaki Miyata; Tsuyoshi Fukudome; Yoshiyuki Ikeda; Takuro Shinsato; Takuro Kubozono; Shoji Fujita; So Kuwahata; Shuichi Hamasaki; Hiroyuki Torii; Soki Lee; Hitoshi Toda; Chuwa Tei
BACKGROUND We developed a Waon therapy (soothing warm therapy) and have previously reported that repeated Waon therapy improves hemodynamics, peripheral vascular function, arrhythmias, and clinical symptoms in patients with chronic heart failure (CHF). The aim of this study was to investigate the effect of Waon therapy on the prognosis of CHF patients. PATIENTS AND METHODS We studied 129 patients with CHF in NYHA functional class III or IV who were admitted to our hospital between January 1999 and March 2001. In the Waon therapy group, 64 patients were treated with a far infrared-ray dry sauna at 60 degrees C for 15 min and then kept on bed rest with a blanket for 30 min. The patients were treated daily for 5 days during admission, and then at least twice a week after discharge. In the control group, 65 patients, matched for age, gender, and NYHA functional class, were treated with traditional CHF therapy. The follow-up time was scheduled for 5 years. RESULTS Recent, complete follow-up data on each patient were obtained. The overall survival rate was 84.5% (Kaplan-Meier estimate). Twelve patients died in the control group and 8 patients died in the Waon therapy group at 60 months of follow-up. Cardiac events due to heart failure or cardiac death occurred in 68.7% of the control group but only 31.3% of the Waon therapy group (P<0.01) at 60 months of follow-up. CONCLUSION Waon therapy reduced cardiac events in patients with CHF. This therapy is a promising non-pharmacological treatment for CHF.
Pacing and Clinical Electrophysiology | 2006
Hitoshi Ichiki; Naoya Oketani; Shuichi Hamasaki; Sanemasa Ishida; Tetsuro Kataoka; Masakazu Ogawa; Keishi Saihara; Hideki Okui; Tsuyoshi Fukudome; Takuro Shinasato; Takuro Kubozono; Yuichi Ninomiya; Takehiko Matsushita; Yutaka Otsuji; Chuwa Tei
Background: Asynchronous electrical activation induced by right ventricular apex (RVA) pacing can cause various abnormalities in left ventricular (LV) function, particularly in the context of severe LV dysfunction or structural heart disease. However, the effect of RVA pacing in patients with normal LV and right ventricular (RV) function has not been fully elucidated. The aim of this study was to characterize the effects of RVA pacing on LV and RV function by assessing isovolumic contraction time and isovolumic relaxation time divided by ejection time (Tei index) and by assessing changes in plasma brain natriuretic peptide (BNP).
Heart and Vessels | 2008
Yuichi Ninomiya; Shuichi Hamasaki; Keishi Saihara; Sanemasa Ishida; Tetsuro Kataoka; Masakazu Ogawa; Koji Orihara; Naoya Oketani; Tsuyoshi Fukudome; Hideki Okui; Tomoko Ichiki; Takuro Shinsato; Takuro Kubozono; Etsuko Mizoguchi; Hitoshi Ichiki; Chuwa Tei
The comparative long-term antianginal efficacy of long-acting nitrates versus calcium channel antagonists remains unclear. The goal of the present study was to compare the coronary endothelial cell function and coronary artery vasoconstriction between patients with normal or mildly diseased coronary arteries treated with long-acting nitrates or calcium channel antagonists. Forty-two patients suspected to have angina pectoris and with normal or mildly diseased coronary arteries underwent Doppler flow study of the left anterior descending coronary artery. All patients were suspected to have angina pectoris and were receiving either long-acting nitrates (n = 18; Nitrates group) or calcium channel antagonists (n = 24; Ca-antagonists group) for at least 1 year. Vascular reactivity was assessed by intracoronary administration of papaverine, acetylcholine (Ach), and nitroglycerin using a Doppler guidewire. Segments that showed the greatest constrictive response to Ach were used for assessment of vasoconstriction. The percent increase in coronary blood flow (CBF) and coronary artery diameter (CAD) induced by Ach was significantly smaller in the Nitrates group than in the Ca-antagonists group (33% ± 74% vs 83% ± 77%, P < 0.05; −3% ± 16% vs 11% ± 12%, P < 0.01, respectively). The percent diameter reduction in the region of greatest constrictive response to Ach was significantly greater in the Nitrates group than in the Caantagonists group (44% ± 39% vs 15% ± 32%, P < 0.02). Long-term treatment with long-acting nitrates may produce less favorable effects on coronary endothelial function and the constrictive response to Ach when compared with long-acting calcium channel antagonists in patients with normal or mildly diseased coronary arteries.
Heart and Vessels | 2010
Keishi Saihara; Shuichi Hamasaki; Sanemasa Ishida; Tetsuro Kataoka; Akiko Yoshikawa; Koji Orihara; Masakazu Ogawa; Naoya Oketani; Tsuyoshi Fukudome; Nobuhiko Atsuchi; Takuro Shinsato; Hideki Okui; Takuro Kubozono; Hitoshi Ichiki; So Kuwahata; Etsuko Mizoguchi; Shoji Fujita; Takuro Takumi; Yuichi Ninomiya; Kaai Tomita; Chuwa Tei
An unhealthy lifestyle can increase the risk of cardiovascular disease. However, the mechanism by which lifestyle influences the development of cardiovascular disease remains unclear. Since coronary endothelial function is a predictor of cardiovascular prognosis, the goal of this study was to characterize the effect of enjoying hobbies on coronary endothelial function and cardiovascular outcomes. A total of 121 consecutive patients (76 men, 45 women) with almost normal coronary arteries underwent Doppler flow study of the left anterior descending coronary artery following sequential administration of papaverine, acetylcholine, and nitroglycerin. On the basis of responses to questionnaires, patients were divided into two groups; the Hobby group (n = 71) who enjoyed hobbies, and the Non-hobby group (n = 50) who had no hobbies. Cardiovascular outcomes were assessed at long-term follow-up using medical records or questionnaire surveys for major adverse cardiovascular events (MACE).The average follow-up period was 916 ± 515 days. There were no significant differences in demographics when comparing the two groups. The percent change in coronary blood flow and coronary artery diameter induced by acetylcholine was significantly greater in the Hobby group than in the Non-hobby group (49% ± 77% vs 25% ± 37%, P < 0.05, 4% ± 13% vs −3% ± 20%, P < 0.05, respectively). The MACE rate was significantly lower in the Hobby group than in the Non-hobby group (P < 0.01). Enjoyment of hobbies was the only independent predictor of MACE (odds ratio 8.1 [95% confidence interval 1.60, 41.90], P = 0.01) among the variables tested. In the early stages of arteriosclerosis, enjoying hobbies may improve cardiovascular outcomes via its favorable effects on coronary endothelial function.
Circulation | 2004
Takashi Kihara; Sadatoshi Biro; Yoshiyuki Ikeda; Tsuyoshi Fukudome; Takuro Shinsato; Akinori Masuda; Masaaki Miyata; Shuichi Hamasaki; Yutaka Otsuji; Shinichi Minagoe; Suminori Akiba; Chuwa Tei
Journal of Psychosomatic Research | 2005
Akinori Masuda; Takashi Kihara; Tsuyoshi Fukudome; Takuro Shinsato; Shinichi Minagoe; Chuwa Tei
International Journal of Cardiology | 2008
Hideki Okui; Shuichi Hamasaki; Sanemasa Ishida; Tetsuro Kataoka; Koji Orihara; Tsuyoshi Fukudome; Masakazu Ogawa; Naoya Oketani; Keishi Saihara; Takuro Shinsato; Takahiro Shirasawa; Etsuko Mizoguchi; Takuro Kubozono; Hitoshi Ichiki; Yuichi Ninomiya; Takehiko Matsushita; Mitsuhiro Nakasaki; Chuwa Tei
Coronary Artery Disease | 2007
Etsuko Mizoguchi; Koji Orihara; Shuichi Hamasaki; Sanemasa Ishida; Tetsuro Kataoka; Masakazu Ogawa; Keishi Saihara; Hideki Okui; Tsuyoshi Fukudome; Takuro Shinsato; Takahiro Shirasawa; Hitoshi Ichiki; Takuro Kubozono; Yuichi Ninomiya; Yutaka Otsuji; Chuwa Tei
American Journal of Cardiology | 2004
Tetsuro Kataoka; Shuichi Hamasaki; Sanemasa Ishida; Keishi Saihara; Hideki Okui; Tsuyoshi Fukudome; Takurou Shinsato; Etsuko Mizoguchi; Yuichi Ninomiya; Yutaka Otsuji; Shinichi Minagoe; Chuwa Tei
Journal of Cardiology | 2006
Yuichi Ninomiya; Shuichi Hamasaki; Sanemasa Ishida; Tetsuro Kataoka; Keishi Saihara; Hideki Okui; Koji Orihara; Tsuyoshi Fukudome; Takuro Shinsato; Tomoko Ichiki; Etsuko Mizoguchi; Yutaka Otsuji; Chuwa Tei