Tudor Pinteala

Aplasia cutis congenita of the scalp- what are the steps to be followed? Case report and review of the literature

Aplasia cutis congenita is a rare malformation characterized by localized congenital absence of the skin. It rarely occurs on the trunk and limbs, and can occur in isolation or as part of a heterogeneous group of syndromes. We report a case of a 4-day-old boy with a 5.6-cm- diameter tumor, with a central crust, non-indurate and no inflammatory rim; localized on the scalp and a small, atrophic hairless scar appeared 6 months later (approximately 5cm in length) at the site of the previous tumor.

Common psychocutaneous disorders in children.

The prevalence of psychosomatic disorders among dermatological patients is high but frequently unreported because of difficulties in diagnosing and treating this patient group. Psychiatric and psychological factors may play different roles in the pathogenic mechanism of some skin diseases. The mainstay of diagnosis and treatment is the differentiation between skin disorders associated with psychiatric illness and those of a purely psychiatric nature. Dermatologists and psychiatrists should be aware of this pathology and work together as a team to resolve difficult cases, especially in children. The present paper highlights the psychocutaneous diseases most frequently seen by dermatologists in pediatric population.

Degradation Mechanism Induced by Psoriasis in Human Fingernails: A Different Approach

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Nail Damage (Severe Onychodystrophy) Induced by Acrylate Glue: Scanning Electron Microscopy and Energy Dispersive X-Ray Investigations

Background: Scanning electron microscopy (SEM) and energy dispersive X-ray (EDX) techniques have been used in various fields of medical research, including different pathologies of the nails; however, no studies have focused on obtaining high-resolution microscopic images and elemental analysis of disorders caused by synthetic nails and acrylic adhesives. Methods: Damaged/injured fingernails caused by the use of acrylate glue and synthetic nails were investigated using SEM and EDX methods. Results: SEM and EDX proved that synthetic nails, acrylic glue, and nails damaged by contact with acrylate glue have a different morphology and different composition compared to healthy human nails. Conclusions: SEM and EDX analysis can give useful information about the aspects of topography (surface sample), morphology (shape and size), hardness or reflectivity, and the elemental composition of nails.

Cutaneous larva migrans in a temperate area

Cutaneous larva migrans (CLM) is common in children in tropical and subtropical areas but exceptionally rare in temperate zones.1 We report a case of CLM in a child from a temperate climate country. An 8-year-old boy was seen with a facial skin eruption. The boy lived in an industrialised city in Romania, but spent 2 months of his summer holidays in a rural village, 150 km away, playing with cats and dogs. Initial pruritus on the left cheek was followed by progressive serpiginous erythematous papules along the left aspect of …

Ulcerated Hemangioma - Surveillance Only

Abstract Infantile hemangiomas are reported in 10-12% of children less than 1 year of age, with ulceration in about 5-13% of cases. Little is known about the mechanism of this disease and explanations are still being looked for. We present a 4-month-old female infant with haemangioma on the left buttock; the hemangioma was noticed at 2 weeks of age, progressively enlarging and ulcerated.

Autosensitisation (Autoeczematisation) reactions in a case of diaper dermatitis candidiasis

Diaper dermatitis is the most common cutaneous diagnosis in infants. Most cases are associated with the yeast colonisation of Candida or diaper dermatitis candidiasis (DDC). It is an irritating and inflammatory acute dermatitis in the perineal and perianal areas resulting from the occlusion and irritation caused by diapers. Autoeczematization to a distant focus of dermatophyte infection very rarely presents as DDC. We present a 1-month-old boy with lesion on diaper area (gluteal area, perineum, groin and genitalia) and with clusters of pustules and vesicles on a large erythematous base over the dorsal area of both hands.

“Chemical” surgery in treating basal cell carcinoma in elderly

The incidence of basal cell carcinoma (BCC) has been increasing in the last decades due to population aging and precise diagnosis. The difficulty that physicians face frequently is related to the treatment decision for BCC; when treating BCC, correct and personalized choices must be taken into consideration by selecting from a large variety of therapeutic options such as: surgical excision (“the golden standard therapy”), electrodessication, cryosurgery, radiation therapy, laser, photodynamic therapy, curettage, topical treatment (imiquimod, 5‐fluorouracil, vismodegib), or combining different treatments.

Psoriasis and Vitiligo: An Association or Coincidence?

Both diseases have an underlying immune-inflammatory pathogenesis centered by dendritic cells which are pluripotent with respect to their functions. These cells induce a selective differentiation and proliferation of Th 1 and Th17 lymphocytes implicated in psoriasis; on the other hand similar dendritic cells (Langerhans cells) are implicated in inducing a cytotoxic effect on melanin producing cells resulting in vitiligo. Usually these pathways are genetically determined and linked to each other: psoriasis, rheumatoid arthritis, diabetes, lupus and some neurodegenerative diseases. In some cases the pathways cross themselves and, dependent on the environment, the manifestations are psoriasis or vitiligo. One may forget that both diseases can be trauma induced (Koebner phenomenon).

Steatocystoma multiplex - case report

Steatocystoma multiplex is a rare, benign, sporadic or familial disorder (autosomal dominant mutation in Keratin 17). Diagnosis is based on clinical grounds: multiple cysts, localized in axilla, groin, neck, scrotum and proximal extremities. We describe a case of Steatocystoma multiplex in a 28 year old male patient with a family history of similar lesions.