Turgay Aslan

Evaluation of mean platelet volume in patients with different degree of coronary collateral develop

1 Ozge Kurmus1, Turgay Aslan1, Ozgur Kirbas2, Cemal Koseoglu3, Tolga Han Efe4, Mehmet Bilge5 1Department of Cardiology, Ufuk University Faculty of Medicine, Ankara, 2Department of Cardiology, Yuksek Ihtisas University, Ankara, 3Department of Cardiology, Tokat State Hospital, Tokat, 4Department of Cardiology, Dıskapı Yıldırım Beyazıt Education and Research Hospital, Ankara, 5Department of Cardiology, Ataturk Education and Research Hospital, Ankara, Turkey Mean platelet volume and coronary collaterals Evaluation of mean platelet volume in patients with different degree of coronary collateral development

Impact of Admission Blood Glucose on Coronary Collateral Flow in Patients with ST-Elevation Myocardial Infarction

In patients with acute myocardial infarction, glucose metabolism is altered and acute hyperglycemia on admission is common regardless of diabetes status. The development of coronary collateral is heterogeneous among individuals with coronary artery disease. In this study, we aimed to investigate whether glucose value on admission is associated with collateral flow in ST-elevation myocardial infarction (STEMI) patients. We retrospectively evaluated 190 consecutive patients with a diagnosis of first STEMI within 12 hours of onset of chest pain. Coronary collateral development was graded according to Rentrop classification. Rentrop 0-1 was graded as poor collateral development, and Rentrop 2-3 was graded as good collateral development. Admission glucose was measured and compared between two groups. Mean admission glucose level was 173.0 ± 80.1 mg/dl in study population. Forty-five (23.7%) patients had good collateral development, and 145 (76.3%) patients had poor collateral development. There were no statistically significant differences in demographic characteristics between two groups. Three-vessel disease was more common in patients with good collateral development (p=0.026). Mean admission glucose level was higher in patients with poor collateral than good collateral (180.6 ± 84.9 mg/dl versus 148.7 ± 56.6 mg/dl, resp., p=0.008). In univariate analysis, higher admission glucose was associated with poor collateral development, but multivariate logistic regression analysis revealed a borderline result (odds ratio 0.994, 95% CI 0.989–1.000, p=0.049). Our results suggest that elevated glucose on admission may have a role in the attenuation of coronary collateral blood flow in acute myocardial infarction. Further studies are needed to validate our results.

Serum Paraoxonase Levels are Correlated with Impaired Aortic Functions in Patients with Chronic Kidney Disease

BACKGROUND The correlation between aortic functions and paraoxonase levels has been previously demonstrated by several earlier studies. In this study, we aimed to investigate the correlation between serum paraoxonase levels and aortic functions among patients with chronic kidney disease. METHODS Our study enrolled 46 chronic kidney disease patients and 45 healthy controls. From these patients, serum cholesterol, creatinine, hemoglobin, and paraoxonase-1 levels were analyzed. RESULTS Paraoxonase-1 levels were significantly lower in patients with chronic kidney disease compared to the controls (p < 0.001). Additionally, the extent of aortic stiffness index (%) was significantly higher in chronic kidney disease patients, but aortic strain and aortic distensibility were significantly higher in healthy controls (p < 0.001, p < 0.001, and p < 0.001, respectively). We further found that paraoxonase-1 levels were correlated with aortic stiffness index, aortic strain, and aortic distensibility (p < 0.001, p < 0.001, and p < 0.001, respectively). CONCLUSIONS Our study demonstrated that serum paraoxonase-1 levels were significantly correlated with impaired aortic functions. The results of this study highlight the impact of serum paraoxonase-1 activity on atherosclerosis and cardiovascular adverse events. KEY WORDS Aortic functions; Atherosclerosis; Chronic kidney disease; Echocardiography; Paraoxonase.

Safety of Transesophageal Echocardiography-Guided Atrial Septostomy: Outcomes of the Largest series of TEE-guided Atrial Septostomy in Turkey

PP-375 Atrial septostomy (AS) is a complex technique used during interventions such as; mitral balloon valvotomy, electrophysiological procedures, left atrial appendage closure and MitraClip. Cardiac perforation occurs in 1-5% of cases even in experienced hands. In daily practice, although AS is

Carotid Artery Back Pressure and Cerebral Intolerance During the Occlusion in Carotid Stenting with the Mo.Ma Proximal Embolic Protection Device

OP-173 The Mo.Ma proximal embolic protection system provide neuroprotection during all phases of the carotid artery stenting (CAS) procedure. However, cerebral intolerance is not an infrequent occurrence with this approach. In most of the cases, intolerance is a benign phenomenon which resolves