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Dive into the research topics where Uday Kumar Neelam is active.

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Featured researches published by Uday Kumar Neelam.


RSC Advances | 2016

Highly enantioselective bioreduction of 1-(3,4-difluorophenyl)-3-nitropropan-1-one: key intermediate of ticagrelor

Manpreet Singh; Hare Krishnen; Uday Kumar Neelam; Kavitha Charugondla; Goverdhan Gilla; Karen Holt-Tiffin; Rakeshwar Bandichhor

A simple, highly effective and economical whole-cell mediated process was developed for the biocatalytic reduction of a ketone, intermediate in the synthesis of platelet inhibiting drug ticagrelor. Sixteen different microorganisms were screened for the bioreduction of 1-(3,4-difluorophenyl)-3-nitropropan-1-one (1) to (S)-1-(3,4-difluorophenyl)-3-nitropropan-1-ol (2). Growing as well as resting cells of Candida parapsilosis 104659 exhibited high conversion (>99.0%) and enantioselectivity (98.0%) for the S-enantiomer.


Archive | 2007

Processes for the preparation of cinacalcet

Pratap Reddy Padi; Surya Prabhakar Akundi; Sashi Kanth Suthrapu; Naveen Kumar Kolla; Vijaya Kumar Kotagiri; Uday Kumar Neelam; Sudhakar Reddy Baddam; Nagaraju Manne


Archive | 2007

Methods for preparing cinacalcet hydrochloride

Pratap Reddy Padi; Surya Prabhakar Akundi; Sashi Kanth Suthrapu; Naveen Kumar Kolla; Vijaya Kumar Kotagiri; Uday Kumar Neelam; Sudhakar Reddy Baddam; Nagaraju Manne; Surya Narayana Devarakonda; Ram Thaimattam; Balaji Raghupati; Satish Kumar Vasamsetti


Organic Process Research & Development | 2010

An Improved Process for the Production of Lansoprazole: Investigation of Key Parameters That Influence the Water Content in Final API

Srinivas Gangula; Chandrasekhar Ravi Ram Elati; Anitha Neredla; Sudhakar Reddy Baddam; Uday Kumar Neelam; Rakeshwar Bandichhor; Ashok Dongamanti


Archive | 2010

Preparation of decitabine

Naveen Kumar Kolla; Uday Kumar Neelam; Sudhakar Reddy Baddam; Srinivas Gangula


Organic Process Research & Development | 2015

Investigation of a Kumada Cross Coupling Reaction for Large-Scale Production of (2S, 7R, E)-2-Isopropyl-7-(4-methoxy-3-(3-methoxypropoxy)benzyl)-N,N,8-trimethylnon-4-enamide

Srinivas Gangula; Uday Kumar Neelam; Sudharkar Reddy Baddam; Vilas H. Dahanukar; Rakeshwar Bandichhor


Archive | 2014

Zinc triflate catalyzed synthesis of thioethers

Sudhakar Reddy Baddam; Uday Kumar Neelam; Naga Raju Manne; Panasa Reddy Adulla; Rakeshwar Bandichhor


Archive | 2011

Procédé pour préparer l'aliskirène et ses intermédiaires

Kaliyaperumal Srinivasan Appaye; Sudhakar Reddy Baddam; Vilas H. Dahanukar; Kiran Kumar Doniparthi; Srinivas Gangula; Rajeshwar Reddy Govindapur; Suju C. Joseph; Naveen Kumar Kolla; Shyam Kumar Unniaranpurakkal Kunhimon; Nagaraju Manne; Mohan Moovendan; Uday Kumar Neelam; Satish P. Nikumbh


Archive | 2011

Process for preparing aliskiren and its intermediates

Kaliyaperumal Srinivasan Appaye; Sudhakar Reddy Baddam; Vilas H. Dahanukar; Kiran Kumar Doniparthi; Srinivas Gangula; Rajeshwar Reddy Govindapur; Suju C. Joseph; Naveen Kumar Kolla; Shyam Kumar Unniaranpurakkal Kunhimon; Nagaraju Manne; Mohan Moovendan; Uday Kumar Neelam; Satish P. Nikumbh


Archive | 2010

Préparation de décitabine

Naveen Kumar Kolla; Uday Kumar Neelam; Sudhakar Reddy Baddam; Srinivas Gangula

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Nagaraju Manne

Dr. Reddy's Laboratories

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