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Dive into the research topics where Uffe Læssøe is active.

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Featured researches published by Uffe Læssøe.


Journals of Gerontology Series A-biological Sciences and Medical Sciences | 2013

Efficacy of Nintendo Wii Training on Mechanical Leg Muscle Function and Postural Balance in Community-Dwelling Older Adults: A Randomized Controlled Trial

Martin Grønbech Jørgensen; Uffe Læssøe; Carsten Hendriksen; Ole Nielsen; Per Aagaard

BACKGROUND Older adults show increased risk of falling and major risk factors include impaired lower extremity muscle strength and postural balance. However, the potential positive effect of biofeedback-based Nintendo Wii training on muscle strength and postural balance in older adults is unknown. METHODS This randomized controlled trial examined postural balance and muscle strength in community-dwelling older adults (75±6 years) pre- and post-10 weeks of biofeedback-based Nintendo Wii training (WII, n = 28) or daily use of ethylene vinyl acetate copolymer insoles (controls [CON], n = 30). Primary end points were maximal muscle strength (maximal voluntary contraction) and center of pressure velocity moment during bilateral static stance. RESULTS Intention-to-treat analysis with adjustment for age, sex, and baseline level showed that the WII group had higher maximal voluntary contraction strength (18%) than the control group at follow up (between-group difference = 269 N, 95% CI = 122; 416, and p = .001). In contrast, the center of pressure velocity moment did not differ (1%) between WII and CON at follow-up (between-group difference = 0.23 mm(2)/s, 95% CI = -4.1; 4.6, and p = .92). For secondary end points, pre-to-post changes favoring the WII group were evident in the rate of force development (p = .03), Timed Up and Go test (p = .01), short Falls Efficacy Scale-International (p = .03), and 30-second repeated Chair Stand Test (p = .01). Finally, participants rated the Wii training highly motivating at 5 and 10 weeks into the intervention. CONCLUSIONS Biofeedback-based Wii training led to marked improvements in maximal leg muscle strength (maximal voluntary contraction; rate of force development) and overall functional performance in community-dwelling older adults. Unexpectedly, static bilateral postural balance remained unaltered with Wii training. The high level of participant motivation suggests that biofeedback-based Wii exercise may ensure a high degree of compliance to home- and/or community-based training in community-dwelling older adults.


Journal of Negative Results in Biomedicine | 2007

Fall risk in an active elderly population – can it be assessed?

Uffe Læssøe; Hans Christian Hoeck; Ole Simonsen; Thomas Sinkjær; Michael Voigt

BackgroundFalls amongst elderly people are often associated with fractures. Training of balance and physical performance can reduce fall risk; however, it remains a challenge to identify individuals at increased risk of falling to whom this training should be offered. It is believed that fall risk can be assessed by testing balance performance. In this study a test battery of physiological parameters related to balance and falls was designed to address fall risk in a community dwelling elderly population.ResultsNinety-four elderly males and females between 70 and 80 years of age were included in a one year follow-up study. A fall incidence of 15% was reported. The test battery scores were not different between the fallers and non-fallers. Test scores were, however, related to self-reported health. In spite of inclusion of dynamic tests, the test battery had low fall prediction rates, with a sensitivity and specificity of 50% and 43% respectively.ConclusionIndividuals with poor balance were identified but falls were not predicted by this test battery. Physiological balance characteristics can apparently not be used in isolation as adequate indicators of fall risk in this population of community dwelling elderly. Falling is a complex phenomenon of multifactorial origin. The crucial factor in relation to fall risk is the redundancy of balance capacity against the balance demands of the individuals levels of fall-risky lifestyle and behavior. This calls for an approach to fall risk assessment in which the physiological performance is evaluated in relation to the activity profile of the individual.


Human Movement Science | 2008

Residual attentional capacity amongst young and elderly during dual and triple task walking

Uffe Læssøe; Hans Christian Hoeck; Ole Simonsen; Michael Voigt

Walking is considered an automatic function which demands little attentional resources. Thus a residual attentional capacity is available for a concurrent task (dual task). Minor age-related deficits in postural control may minimize the residual attentional capacity, however this may not be detected by a simple examination of the individuals gait performance. This study investigated the use of challenging dual task combinations to detect age related changes in gait performance. Eleven community-dwelling elderly (mean age 76 years) and 13 young subjects (mean age 26 years) participated in the study. The participants walked along a figure-of-eight track at a self-selected speed. The effect of introducing a concurrent cognitive task and a concurrent functional motor task was evaluated. Stride-to-stride variability was measured by heel contacts and by trunk accelerometry. In response to the cognitive task the elderly increased their temporal stride-to-stride variability by 39% in the walking task and by 57% in the combined motor task. These increases were significantly larger than observed for the young. Equivalent decreases in trunk acceleration autocorrelation coefficients and gait speed were found. A combination of sufficiently challenging motor tasks and concurrent cognitive tasks can reveal signs of limited residual attentional capacity during walking amongst the elderly.


Gait & Posture | 2012

Time-of-day influences postural balance in older adults

Martin Grønbech Jørgensen; Michael Skovdal Rathleff; Uffe Læssøe; Paolo Caserotti; Ole Nielsen; Per Aagaard

BACKGROUND Postural balance assessments are performed in both clinical and basic research settings on a daily basis. During a 24-h time span our physiology and physical performance undergo radical changes as we are influenced by the circadian rhythm. The time-of-day interaction on postural balance is unknown in older adults. The aim of this study was to investigate the time-of-day effect on postural balance in older adults. METHODS Center of pressure (CoP) excursion was measured (100 Hz) by force plate analysis in 34 older adults during 30 s of narrow quiet bilateral stance. Measurements were performed around 9a.m., 12.30 p.m. and 4 p.m. on the same day. Postural balance was quantified by velocity-moment, confidence ellipse area, total sway area and total sway length. RESULTS An overall significant time-of-day (between 9 a.m. and 4 p.m.) effect was observed for velocity-moment (mm(2)/s) 57 ± 27-65 ± 29 (p = 0.001), confidence ellipse area (mm(2)) 36 ± 16-44 ± 19 (p < 0.001), total sway area (mm(2)) 548 ± 263-627 ± 285 (p = 0.001) and total sway length (mm) 373 ± 120-379 ± 113 (p = 0.037). The variation of postural balance was mostly pronounced from midday (12.30 p.m.) toward the afternoon (4 p.m.) in all sway parameters. Specifically between 12.30 p.m. and 4 p.m. confidence ellipse area increased by 18.5%, total sway area by 17.1%, velocity-moment by 15.8% and total sway length by 4.6%. No differences were observed between 9 a.m. and 12.30 p.m. in any of the sway parameters. CONCLUSIONS This study demonstrates that time-of-day influences postural balance in older adults. These findings have important scientific and clinical relevance, as they imply that time-of-day should be a controlled factor when assessing postural balance in older adults.


Nordic Journal of Psychiatry | 2010

Impact of exercise on patients with depression and anxiety

Anne-Marie Oeland; Uffe Læssøe; Anne Vingaard Olesen; Povl Munk-Jørgensen

Background: Persons with common mental disorders are at risk of lowered physical activity. Aims: To investigate if patients with depressive and/or anxiety disorders can achieve a level of physical activity meeting public health recommendations, increase their physical fitness and quality of life (QoL) through participation in a physical exercise programme. Methods: In a non-blinded controlled study, 48 patients referred by private psychiatric clinics and private general practices were either treated in an intervention (n=27) or a control group (n=21). The intervention group took part in 20 weeks of group exercise consisting of aerobic training and non-aerobic weight-lifting. All participants were interviewed and tested at baseline, week 20 and at week 32. Results: The intervention group increased in physical activity (120 min/week) and VO2max (0.48 ml O2/min). The VO2max increase was maintained after a 12-week follow-up period. Findings should be conservatively interpreted because of high attrition rate. Conclusions: Patients with anxiety and/or depressive disorders who participated in a structured, supervised exercise programme achieved in accordance with public health recommendations a higher level of physical activity and VO2max. Clinical implications: The clinical implications of the study may be a suggestion of offering physical exercise to milder and moderate severe cases of depression and anxiety.


Scandinavian Journal of Medicine & Science in Sports | 2004

Modification of stretch tolerance in a stooping position

Uffe Læssøe; Michael Voigt

A stooping (slump) position is believed to add tension to the nerve tissue complex. This study was designed to determine whether this position would have an effect on the stretch tolerance in a passive knee extension. Thirteen healthy individuals were tested. The knee extension was stopped by the subjects at “onset of pain”. Joint range of motion and passive resistance to the extension were recorded in four test situations: upright sitting and stooping position, with the ankle joint in either the neutral or maximal dorsi‐flexed position.


Injury-international Journal of The Care of The Injured | 2015

Incidence and epidemiology of tibial shaft fractures

Peter Larsen; Rasmus Elsøe; Sandra Hope Hansen; Thomas Graven-Nielsen; Uffe Læssøe; Sten Rasmussen

INTRODUCTION The literature lacks recent population-based epidemiology studies of the incidence, trauma mechanism and fracture classification of tibial shaft fractures. The purpose of this study was to provide up-to-date information on the incidence of tibial shaft fractures in a large and complete population and report the distribution of fracture classification, trauma mechanism and patient baseline demographics. METHODS Retrospective reviews of clinical and radiological records. RESULTS A total of 196 patients were treated for 198 tibial shaft fractures in the years 2009 and 2010. The mean age at time of fracture was 38.5 (21.2SD) years. The incidence of tibial shaft fracture was 16.9/100,000/year. Males have the highest incidence of 21.5/100,000/year and present with the highest frequency between the age of 10 and 20, whereas women have a frequency of 12.3/100,000/year and have the highest frequency between the age of 30 and 40. AO-type 42-A1 was the most common fracture type, representing 34% of all tibial shaft fractures. The majority of tibial shaft fractures occur during walking, indoor activity and sports. The distribution among genders shows that males present a higher frequency of fractures while participating in sports activities and walking. Women present the highest frequency of fractures while walking and during indoor activities. CONCLUSION This study shows an incidence of 16.9/100,000/year for tibial shaft fractures. AO-type 42-A1 was the most common fracture type, representing 34% of all tibial shaft fractures.


Journal of Orthopaedic Trauma | 2014

Restrictions in quality of life after intramedullary nailing of tibial shaft fracture: a retrospective follow-up study of 223 cases.

Peter Larsen; Hans Lund; Uffe Læssøe; Thomas Graven-Nielsen; Sten Rasmussen

Objective: To evaluate the long-term outcome after intramedullary nailing of tibial shaft fracture. Design: Retrospective, cross-sectional study. Setting: Level I, Trauma Center. Methods: Retrospective review of 294 patients treated with intramedullary nailing after tibial shaft fracture from 1998 to 2008. The participants completed Knee injury and Osteoarthritis Outcome Score, and these data were compared with published reference population. Intervention: Intramedullary nailing of tibial shaft fracture. Main Outcome Measures: Knee Injury and Osteoarthritis Outcome Score. Results: A total of 223 patients agreed to participate (76%). Mean time of follow-up was 7.9 years. Compared to reference population, the study group reported 44% higher incidence of knee pain, 39% higher incidence of function in daily living limitations, 58% higher incidence of limitations in quality of life, and 60% higher incidence of limitations during sports activities. Comparison of age-related differences between the study group and reference population showed that the age group of 18–34 years reported the most difficulties. Conclusions: Compared with reference population, 60% of the patients experienced limitations in activity and restrictions in quality of life and 44% reported knee pain. This was mainly evident among the young participants. Level of Evidence: Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.


Journal of Aging and Physical Activity | 2014

Intrarater reproducibility and validity of Nintendo Wii balance testing in community-dwelling older adults.

Martin Grønbech Jørgensen; Uffe Læssøe; Carsten Hendriksen; Ole Nielsen; Per Aagaard

The aims of the current study were to examine the intrarater intersession reproducibility of the Nintendo Wii agility and stillness tests and explore the concurrent validity in relation to gold-standard force-plate analysis. Within-day intersession reproducibility was examined in 30 older adults (age 71.8 ± 5.1 yr). No systematic test-retest differences were found for the Wii stillness test; however, the Wii agility test scores differed systematically between test sessions (p < .05). The Wii stillness test yielded a test-retest ICC of .86 (95% CI 0.74-0.93), CV of 6.4%, LOA of 11.0, and LOA% of 17.9%. Likewise for the Wii agility test ICC was .73 (95% CI 0.50-0.86), CV 5.3%, LOA 1.8, and LOA% of 14.6%. Wii stillness scores correlated to force plate measures (r = .65-.82, p < .01), reflecting moderate to excellent validity. In conclusion, it appears that the Wii stillness test represents a low-cost, objective, reproducible, and valid test of undisturbed postural balance in community-dwelling older adults.


Journal of Electromyography and Kinesiology | 2013

Standardized activities of daily living in presence of sub-acute low-back pain: A pilot study

Jacob Handberg Svendsen; Heine Michael Svarrer; Uffe Læssøe; Miriam Marie Rosé Vollenbroek-Hutten; Pascal Madeleine

The aim of this pilot study was to investigate how sub-acute low-back pain (LBP) patients differed with respect to control in movements and muscle activation during standardized tasks representing daily living activities, and explore relationships between cognition and measured motor performance. Linear and nonlinear parameters were computed from kinetics, kinematics and muscle activity recorded for 12 sub-acute patients and 12 healthy matched controls during trunk flexion, sit-to-stand from a chair and lifting a box. Cognitive variables were collected to explore relationships with biomechanical parameters. For trunk flexion, left external abdominal oblique muscle activity level was lower for patients compared with controls (p < 0.05), whereas sample entropy (complexity) was higher (p < 0.05). Normalized mutual information was lower for patients compared with controls for left and right erector spinae (p < 0.05). Level of activity of left external abdominal oblique correlated negatively with cognitive ignoring and positively with catastrophizing (p ≤ 0.05), and catastrophizing also correlated positively with functional connectivity of abdominal muscles (p < 0.05). Signs of reorganization in muscle activation pointed towards different synergistic actions in trunk muscles in sub-acute LBP patients compared with controls. The interplay with maladaptive cognition suggested that in the subacute stage of LBP, both biomechanical and cognitive factors should be taken into account.

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Per Aagaard

University of Southern Denmark

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