Ulrich Bothe
Bayer
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Publication
Featured researches published by Ulrich Bothe.
Bioorganic & Medicinal Chemistry Letters | 2018
Imadul Islam; Shendong Yuan; Christopher West; Marc Adler; Ulrich Bothe; Judi Bryant; Zheng Chang; Kieu Chu; Kumar Emayan; Giovanna Gualtieri; Elena Ho; David Light; Cornell Mallari; John Morser; Gary Phillips; Caralee Schaefer; Drew Sukovich; Marc Whitlow; Deborah Chen; Brad O. Buckman
We report here the design and synthesis of a novel series of benzylamines that are potent and selective inhibitors of uPA with promising oral availability in rat. Further evaluation of one representative (ZK824859) of the new structural class showed that this compound lowered clinical scores when dosed in either acute or chronic mouse EAE models, suggesting that uPA inhibitors of this type could be useful for the treatment of multiple sclerosis.
Archive | 2006
Nico Bräuer; Bernd Buchmann; Christoph Huwe; Bernhard Lindenthal; Gernot Langer; Olaf Peters; Gerd Schubert; Ulrich Bothe; Luisella Toschi; Michaele Peters-Kottig
Archive | 2008
Ingo Hartung; Ulrich Bothe; Georg Kettschau; Ulrich Luecking; Anne Mengel; Martin Krueger; Karl-Heinz Thierauch; Philip Lienau; Ulf Boemer
Archive | 2004
Alexander Hillisch; Olaf Peters; Christian Gege; Wilko Regenhardt; Dirk Kosemund; Gerhard Siemeister; Eberhard Unger; Ulrich Bothe
Archive | 2006
Wolfgang Schwede; Carsten Moeller; Anja Schmidt; Ulrike Fuhrmann; Norbert Schmees; Ulrich Bothe
Archive | 2011
Tim Wintermantel; Carsten Möller; Ulrich Bothe; Reinhard Nubbemeyer; Ludwig Zorn; Dirk Kosemund; Laak Antonius Ter; Rolf Bohlmann; Lars Wortmann; Donald Bierer
Archive | 2008
Ingo Hartung; Ulrich Bothe; Georg Kettschau; Ulrich Luecking; Anne Mengel; Martin Krueger; Karl Heinz Thierauch; Philip Lienau; Ulf Boemer
Archive | 2016
Ulrich Bothe; Antje Margret Wengner; Holger Siebeneicher; Nicole Schmidt; Reinhard Nubbemeyer; Ulf Bömer; Judith Günther; Holger Steuber; Martin Lange; Christian Stegmann; Andreas Sutter; Roland Neuhaus
Archive | 2014
Tim Wintermantel; Carsten Moeller; Ulrich Bothe; Reinhard Nubbemeyer; Ludwig Zorn; Laak Antonius Ter; Rolf Bohlmann; Lars Wortmann
Cancer Research | 2018
Martin Lange; Antje Margret Wengner; Ulrich Bothe; Ulf Boemer; Reinhard Nubbemeyer; Holger Siebeneicher; Holger Steuber; Judith Guenther; Lisette Potze; Nicole Schmidt; Oliver Politz; Wolf-Dietrich Doecke; Eleni Lagkadinou; Thomas Matthias Zollner; Franz von Nussbaum; Dominik Mumberg; Andreas Steinmeyer; Michael Brands; Karl Ziegelbauer
