V. B. Pandey

Anti-inflammatory effect of (+) -pinitol

In the carrageenin-induced paw oedema in rats, (+)-pinitol (2.5-10 mg/kg, i.p.), isolated from Abies pindrow leaves, showed a significant anti-inflammatory effect, the highest dose being comparable to phenylbutazone (100 mg/kg, i.p.).

Effect of berberine and (+/-)-bicuculline isolated from Corydalis chaerophylla on spore germination of some fungi.

Berberine and (±)-bicuculline were isolated from roots and leaves, respectively, ofCorydalis chaerophylla. Both were effectivein vitro against spore germination of some plant pathogenic fungi (Alternaria brassicicola, A. brassicae, A. cheiranthi, A. melongenae, A. solani, Colletotrichum musae, C. falcatum, Curvularia penniseti, C. lunata, C. maculans, C. pallescens, Curvularia sp.,Erysiphe pisi, E. cichoracearum, Erysiphe sp.,Fusarium udum, Helminthosporium spiciferum, H. penniseti, H. frumentacei, Heterosporium sp.,Oidium erysiphoides andUstilago cynodontis). Berberine and (±)-bicuculline significantly inhibited spore germination of all the fungi at concentrations of 100–1000 ppm. Berberine was effective against all the fungi at all concentrations; most of the fungi did not germinate at 1000 ppm.H. penniseti conidia did not germinate at any cencentration of (±)-bicuculline.U. cynodontis was the least sensitive fungus at lower concentrations but 800 ppm dose was highly effective.

Cyclopeptide alkaloids from Zizyphus jujuba

A new cyclopeptide alkaloid, jubanine-C (1), together with known alkaloids scutianine-C (4) and zizyphine-A (5), have been isolated from the stem bark of Zizyphus jujuba and identified by spectral analysis.

Efficacy of alkaloid (-)-corypalmine against spore germination of some fungi.

Inhibition activity of the alkaloid (−)-corypalmine on spore germination of plant pathogenic and saprophytic fungi (Alternaria solani, A brassicicola, A. brassicae, A. melongenae, Curvularia pallescens, C. lunata, C. maculans, Curvularia sp.,Colletotrichum sp.,Helminthosporium speciferum, H. frumentacei, H. pennisetti, Heterosporium sp.,Penicillum sp.,Ustilago cynodontis) was determined. Spore germination of all the tested fungi was inhibited,Heterosporium sp. andUstilago cynodontis being the most sensitive (complete inhibition of spore germination was observed at the very low concentration of 200 ppm).Curvularia palliscens, C. maculans andCurvularia sp. were less sensitive; complete inhibition of spore germination occurred at 400 ppm.

Eclalbatin, a Triterpene Saponin from Eclipta Alba

Abstract From the whole plant of Eclipta alba, a new triterpene saponin, named eclalbatin, together with α-amyrin, ursolic acid and oleanolic acid were isolated. The structure of eclalbatin has been established as 3-0-β-D-glucopyranosyl-3-β-hydroxy-olean-12-en-28-oic acid, 28-0-β-D-arabino-pyranoside (1) on the basis of chemical and spectral data.

Triterpenoid saponins from the stem bark of Symplocos spicata

Abstract From the stem bark of Symplocos spicata a mixture of triterpenoid saponins was obtained. It behaved as a pure compound in TLC and HPLC, but heterogeneity was suspected on the basis of chemical and NMR spectral data. It was separated to give two analogous glycosides, which were identified as 3,28- O -bis-β- d -glucopyranosides of 19α-hydroxyarjunolic and 19α-hydroxyasiatic acids.

Arjunolitin, a triterpene glycoside fromTerminalia arjuna

Abstract Arjunolic acid diglycoside, which we have named arjunolitin, has earlier been reported from Terminalia arjuna . Its structure has now been established as 3- O -β- d -glycopyranosyl 2α,3β-23-tri-hydroxyolean-12-en-28-oic acid 28- O -β- d -glucopyranoside by chemical and spectral data.

Peptide alkaloids from Zizyphus species

Abstract The isolation of cyclopeptide alkaloids, frangufoline from Zizyphus jujuba and Z. nummularia , amphibine-H and nummularine-K from Z. xylopyra and nummularine-R, a new 13-membered cyclopeptide alkaloid, from Z. nummularia is reported. The structure of the new alkaloid was elucidated by spectroscopic methods and by chemical degradation.

TRITERPENE GLYCOSIDE FROM TERMINALIA ARJUNA

Abstract A new triterpene glycoside, arjunetoside, together with oleanolic and arjunic acids has been isolated from the root bark of Terminalia arjuna. The structure of arjunetoside has been established as 3-O-β-D-glucopyranosyl-2α,3β, 19α-trihydroxyolean-12-en-28-oic acid, 28-O-β-D-glucopyranoside by chemical and spectral data.

Antifungal activity of Nor-securinine Against Some Phytopathogenic Fungi

Crude extracts and active principles from medicinal plants have shown potential role in controlling plant diseases in glasshouses as well as in fields as one of the safest and eeofriendly methods. The effect of nor-seeurinine (an alkaloid) isolated from Phyllanthus amarus has been seen against spore germination of some fungi (Alternaría brassicae, A soiani, Curvularia pennisetti, Curvularia sp., Erysiphe pisi, Helminthosporium frumentacei) as well as pea powdery mildew (Erysiphe pisi) under glasshouse conditions. The sensitivity of fungi to nor-seeurinine varied considerably. Nor-seeurinine was effective against most of the fungi. H. frumentacei was more sensitive even at the lowest concentration ( 1,000 μg/ml). Likewise conidia of E, pisi were also inhibited in partially or completely appressorium formation. Pre-inoeulation treatment showed greater efficacy than post-inoculation in inhibiting powdery mildew development on pea plants in a glasshouse. Maximum inhibition occurred at 2000 μg/ml.