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Featured researches published by V. De Santis.


Osteoarthritis and Cartilage | 2003

Reliability of the Ahlbäck classification of knee osteoarthritis

Marco Galli; V. De Santis; L. Tafuro

OBJECTIVE The aim of the study was to assess the inter-observer reliability and intra-observer reproducibility of the Ahlbäck radiographic classification for knee osteoarthritis (OA). DESIGN Ninety-six knee radiographs of patients with clinical signs of arthritis were evaluated and classified into five grades of Ahlbäck classification by three observers with different experience. The evaluation was repeated after 1 month. The inter- and intra-rater agreements were assessed by statistical analysis (k and k(w)coefficients). RESULTS The inter-observer agreement was statistically significant, but with low or medium values of the coefficients. The intra-rater agreement was less significant than the inter-rater. Inter- and intra-rater agreement coefficients decreased when the cases of stage V arthritis were excluded from the analysis. The evaluations were influenced by the age and working experiences of each observer. CONCLUSIONS The authors stress that the Ahlbäck classification, as routinely applied, should not be used in orthopaedic surgery without the support of clinical and/or arthroscopic examinations, because of its poor reliability.


Hip International | 2001

Analysis of the Catastrophic Failure of a THR: The Role of the Acetabular Component

G. Maccauro; C. Piconi; Luca Proietti; M. Timpanaro; V. De Santis; G. Magliocchetti; E. De Santis

This paper investigates the failure of a total hip prosthesis due to the disruption of the PE inlay and the Ti-alloy metal back of the acetabular component. The PE inlay was coupled with an alumina ball head. The case analysis showed that the initiator of the failure was the size selection of the prosthesis, followed by the positioning of the acetabular component. The deformation of the PE inlay leads to rupture of the inlay itself, followed by the direct contact between the alumina ball head and the titanium alloy cup, causing the disruption of the Ti-alloy metal back, with massive release of wear debris in the surrounding tissues.


Archive | 2004

Pathophysiology of Avascular Necrosis of the Femoral Head

E. De Santis; Luca Proietti; V. De Santis; G. Falcone

The interruption of arterial blood flow in the superior segment of the femoral epiphysis is a common event in pathological conditions, e.g., gas embolism in Caisson disease, traumatic vessel injuries in neck femoral fractures or hip dislocation, vascular occlusion in Gaucher’s disease, sickle cell anemia, and radiation exposure. When arterial blood impairment occurs without a documented etiology, the term idiopathic avascular necrosis must be employed.


Joints | 2017

Ceramic Total Knee Arthroplasty: Ready to Go?

G. Solarino; C. Piconi; V. De Santis; A. Piazzolla; B. Moretti

Total knee arthroplasty (TKA) is a well-established surgical procedure in the late stages of knee osteoarthritis. Nevertheless, this procedure is associated with a percentage of unsatisfactory results and biomechanical failures, with aseptic loosening being the most common cause of revision. Beside these problems, cutaneous and systemic hypersensitivity reactions to metals have arisen as an increasing concern after joint arthroplasties, even if allergies against implant materials are still a quite rare and not well-known problem. Ceramic composites have been recently used in prosthetic components, showing minimum wear and excellent long-term results in total hip replacement, due to their high resistance to scratching and their better wettability with respect to cobalt–chromium alloy. Furthermore, the biologic response to debris generated from these bearings is less aggressive. Knee joint simulator tests and clinical results demonstrate promising results of TKAs with ceramic components that should led to benefit for the patients.


Hip International | 2003

Ultrastructural analysis of retrieved ceramic ball heads

G. Maccauro; L. Pilloni; L. Petrella; L. Proietti; V. De Santis; F. Muratori; Corrado Piconi

Surface modification of alumina heads retrieved for aseptic loosening (6 cases) has been analysed using scanning electron microscopy, coupled with energy dispersive X-ray microanalysis. Ultrastruct...


Hip International | 2001

In Vivo Histological Analysis of Bone Hydroxyapatite Interface: A Case Report in a Post-Traumatic Femoral Fracture

T. Nizegorodcew; G. Maccauro; G. Falcone; V. De Santis; Michele Attilio Rosa

The authors analysed the bone implant interface in a hydroxyapatite (HA) coated titanium alloy stem in a femoral fracture occurring 2 years after operation following a trauma, in the absence of any clinical symptoms of failure. A comparison between the coated and the uncoated part was made. In the coated region of the stem, connective tissue with collagen fibres perpendicularly orientated to the implant was observed, increasing stability of the system. On the contrary, in the uncoated part, fibres were orientated in parallel with less stability.


International Orthopaedics | 2003

Osseointegration in hip prostheses: experimental study in sheep

C. Doria; V. De Santis; G. Falcone; Luca Proietti; E. De Santis


Key Engineering Materials | 2000

Histological and Ultrastructural Analysis of Alumina Wear Debris

E. De Santis; G. Maccauro; Luca Proietti; G. Falcone; V. De Santis


Orthopaedic Proceedings | 2004

CELL REACTION AND BONE RESPONSE TO ZIRCONIA CERAMICS: EXPERIMENTAL STUDY

Enrico Pola; V. De Santis; G. Maccauro; Corrado Piconi; G. Gasparini; E. De Santis


Orthopaedic Proceedings | 2004

A PROSPECTIVE STUDY ON A NEW POROUS COATED AND HA STEM: 3 YRS F-U

E. De Santis; Giandomenico Logroscino; V. De Santis; L. Giannotta; F. Silvi; S. Rivelli

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G. Maccauro

Catholic University of the Sacred Heart

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E. De Santis

Sapienza University of Rome

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G. Falcone

The Catholic University of America

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Luca Proietti

The Catholic University of America

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E. De Santis

Sapienza University of Rome

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Corrado Piconi

Catholic University of the Sacred Heart

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G. Gasparini

Catholic University of the Sacred Heart

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A. Menghi

The Catholic University of America

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C. Piconi

National Research Council

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G. Magliocchetti

The Catholic University of America

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