V. Sivanesaratnam

Malignant Evolution with Fatal Outcome in a Patient with Partial Hydatidiform Mole

Summary: Recent studies suggest that partial hydatidiform moles are not potentially malignant and that prophylactic chemotherapy need not be administered. Our experience does not support that opinion. We report a 28‐year‐old Malay primigravida who succumbed to choriocarcinoma complicating a partial mole. The partial mole is likely to be part of a spectrum of gestational trophoblastic disease and should be viewed as a potentially malignant lesion.

Epidural analgesia in primigravidae in spontaneous labour at term: a prospective study.

Objectives: To prospectively study the intervention rate, duration of labour, malpositions, fetal outcome, maternal satisfaction, voiding complications and adverse events in healthy primigravidae in spontaneous labour at term following epidural analgesia.

Eisenmenger Syndrome in Pregnancy

4. Sand PK, Bowen LW, Ostergard DR. Uninhibited urethral relaxation: An unusual cause of incontinence. Obstet Gynecol 1986; 68: 645-648. 5. Kulseng-Hanssen S. Prevalence and pattern of unstable urethral pressure in one hundred and seventy four gynecological patients referred for urodynamic investigation. Am J Obstet Gynecol 1983; 146: 895-900. 6. Cardozo LD, Versi E. Urethral instability in normal postmenopausal patients. Proc 15th Annual Meeting ICS London 1985; 115-116. 7. Tapp AJS, Cardozo LD, Versi E, Studd JWW. The prevalence of variation of resting urethral pressure in women and its association with lower urinary tract function. Brit J Urol 1988; 61: 314-317. 8. Versi E. Relevance of urethral pressure profilometry to date. In: Drife JO, Hilton P, Stanton S. Micturition, 1st Edition, London, Springer Verlag, 1989; 6: 81-97. 9. Blaivas JG, Labib KL, Bauer SB, Retck AB. A new approach to electromyography of the external urethral sphincter. J Urol 1977; 117: 773-717. 10. Scott RJ, Ostergard DR. Urethral syndrome. In: Ostergard DR, Bent AE. Urogynecology and Urodynamics Theory and Practice, 3rd Edition. Baltimore, Williams and Wilkins 1991; 2 4 264. 11. Jarvis GL. The management of urinary incontinence due to primary vesical sensory urgency by bladder drill. Brit J Uroll982; 54: 374-376. 12. Kulseng-Hanssen S. Pudendal block in female patients with unstable urethral pressure. Proc 14th Annual Meeting ICS 1984. Innsbruck 118-120. 13. Hindmarsh JR, Gosling PT, Deane AM. Bladder instability. Is the primary defect in the urethra? Brit J Urol 1983; 55: 648-651. 14. Bergman A, Koonings PP, Ballard CA. Detrusor instability. Is the bladder the cause or effect? Neurourol Urodynam 1988; 7: 186. 15. Barbalias GA, Meares EM. Female urethral syndrome, clinical and urodynamic perspectives. Urology 1984; 2: 208-212. 16. Lose G, Jorgensen L. Effect of urethral catheterization on urethral sphincter EMG and pressure profile. Neurourol Urodynam 1989; 8: 473-480.

AGGRESSIVE ANGIOMYXOMA OF THE VULVA WITH AN UNUSUAL VASCULAR FINDING

&NA; We report the first documented Malaysian case of aggressive angiomyxoma (AAM) of the vulva. A 56‐yr‐old woman of Indian ethnic origin presented with a vulval lesion which was clinically mistaken for a Bartholins cyst. The lesion was surgically excised and a diagnosis of AAM was made histologically. Of particular interest was the finding of foamy and mononuclear inflammatory cells and fibrin in the walls of most of the lesional blood vessels. The patient recovered uneventfully and remains without tumor recurrence at the time of writing 37 mths after initial presentation.

Human papillomavirus in cervical cancers of Malaysians

Aim:  With cervical carcinoma remaining the second leading cancer among Malaysian women, it is imperative to clarify the prevalence of human papillomavirus (HPV) in this respect, considering the dearth of local information.

Recent Trends in Histological Pattern of Cervical Carcinoma among Three Ethnic Groups in Malaysia

Objective: To study the trend of different histological types of cervical carcinoma among the 3 major ethnic groups in Malaysia.

Scleroderma and Pregnancy

Summary: A case of pregnancy complicated by scleroderma is reported. Although the disease runs a variable course during pregnancy, maternal mortality is a likely sequel once renal involvement occurs. General systemic deterioration occurred in this patient during pregnancy, but there was a remarkable recovery after delivery.

Advanced Extrauterine Pregnancy Mimicking Intra‐Uterine Fetal Death: Case Reports

Summary: Two cases of late second trimester extrauterine pregnancy are presented — intraabdominal pregnancy in one and an ampullary pregnancy in another. In the former the diagnosis was made only after attempts at induction of labour for fetal death with prostaglandins failed and in the latter only at laparotomy. The diagnostic and surgical problems encountered are discussed.

Acute Pancreatitis in Pregnancy

Summary: Two patients with acute pancreatitis in pregnancy are described and some pertinent features in these and other reported series are discussed.

Fertility and Gynaecologic Malignancies

Fertility and gynaecological malignancies have an important relationship. A clear inverse relationship exists between family size and the incidence of ovarian and endometrial cancer.