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Featured researches published by V. Sparac.


Journal of Ultrasound in Medicine | 2001

Preoperative evaluation of pelvic tumors by Doppler and three-dimensional sonography.

Asim Kurjak; Sanja Kupesic; V. Sparac; Ivanka Bekavac

To study a spectrum of systems (two‐dimensional transvaginal, transvaginal color Doppler, three‐dimensional, three‐dimensional power Doppler, and contrast‐enhanced three‐dimensional power Doppler sonography) for preoperative evaluation of pelvic tumors.


Gynecologic Oncology | 2003

The detection of stage I ovarian cancer by three-dimensional sonography and power Doppler

Asim Kurjak; Sanja Kupesic; V. Sparac; Matija Prka; Ivanka Bekavac

OBJECTIVE The objective was to determine the diagnostic accuracy of three-dimensional (3D) sonography and 3D power Doppler imaging, used together with standard 2D transvaginal grayscale and color/power Doppler modalities, for preoperative sonographic assessment of suspected ovarian lesions. METHODS Five-year retrospective analysis was performed by our experts on ultrasonography and surgery on the reports from 43 referred patients with suspected stage I ovarian cancer. All patients were evaluated during the week prior to surgery at our department. Preoperative sonographic assessment included careful examination of ovarian volume, morphology, and vascularity by four complementary sonographic methods. Scoring systems combining morphological and Doppler parameters were adopted for 2D and 3D sonographic examinations. Final diagnosis was confirmed by a histopathologist. RESULTS Out of the 43 stage I ovarian cancers, 42 cases were successfully detected preoperatively by four complementary sonographic methods. Only 30 (69.8%) and 37 (86.1%) cases of stage I ovarian cancer were detected by 2D grayscale and combined 2D grayscale and color Doppler sonography, respectively. Morphological analysis obtained by 3D sonography alone detected 32 of 43 ovarian malignancies, reaching a diagnostic rate of 74.4%. Qualitative analysis of tumor vascularity architecture by 3D power Doppler significantly improved the sonographic management process and successfully detected 41 cases of stage I ovarian cancer (95.4%). When morphological features obtained by 3D sonography were added to 3D power Doppler findings, we achieved an even higher diagnostic accuracy of 97.7%. We found a statistically significant difference (P </= 0.01) in diagnostic rates of 3D power Doppler, and especially the combined use of 3D sonography and 3D power Doppler in comparison to those obtained with transvaginal 2D grayscale (P </= 0.002 and P </= 0.001, respectively) or 3D sonography (P </= 0.006 and P </= 0.002, respectively). CONCLUSIONS In comparison to transvaginal 2D grayscale or 3D sonography, 3D power Doppler and especially the combined use of 3D sonography and power Doppler imaging significantly improve diagnostic accuracy in preoperative sonographic assessment of suspected ovarian lesions.


Journal of The American Association of Gynecologic Laparoscopists | 2001

Histologic architecture and vascularization of hysteroscopically excised intrauterine septa.

V. Sparac; Sanja Kupesic; Marijan Ilijaš; Tina Zodan; Asim Kurjak

STUDY OBJECTIVE To investigate histologic structures of intrauterine septa resected hysteroscopically. DESIGN Prospective, consecutive study (Canadian Task Force classification II-2). SETTING University-affiliated hospital. PATIENTS Seventy-six women evaluated for uterine septa and infertility. INTERVENTIONS All patients with diagnosis of uterine septum detected by transvaginal color Doppler (TVCD) underwent operative hysteroscopy in which the most prominent part of the septum was encircled with a hysteroscopic loop electrode and removed. Specimens were sent for histopathologic evaluation. The rest of the septum was divided by monopolar needle electrode until the uterine cavity assumed a globular shape. MEASUREMENTS AND MAIN RESULTS In 63 women (82.8%) preoperative TVCD revealed septal vascularity typical for radial arteries with mean resistance flow of 0.64 +/- 0.06, and enlarged sunusoidal and capillary spaces. Histopathologic results revealed fibromuscular tissue with moderately more connective tissue in 55 cases (72.3%) and myometrial tissue in 21 (27.6%). There was no statistically significant difference (p >0.05) in frequency of septa between patients with primary and secondary infertility. CONCLUSION Intrauterine septa consisted of the same type of tissue as normal myometrium, with many muscular fibers. We suspect that muscular tissue within the uterine septum is a potential cause of irregular contractility and consequently increased abortion rate in these patients. (J Am Assoc Gynecol Laparosc 8(1):111-116, 2001)


The Ultrasound Review of Obstetrics & Gynecology | 2001

Three-dimensional ultrasound and three-dimensional power Doppler in the assessment of adnexal masses

Asim Kurjak; V. Sparac; Sanja Kupesic; Ivanka Bekavac

ABSTRACTThree-dimensional ultrasound is a new, emerging technology that provides additional information for the evaluation of ovarian tumors. Multiplanar and volume-rendering display methods combined with the ability to rotate volume data into standard orientations are essential components of the current and future success of three-dimensional ultrasound.Increasing knowledge about three-dimensional ultrasound, as well as improved handling allow application of this method to the field of gynecological oncology. The recent development of real-time three-dimensional ultrasound imaging will further advance the clinical applications, particularly in the assessment of pelvic tumors. The introduction of the three-dimensional power Doppler systems may improve the information available on ovarian tumor vascularity and speed up the entire patient management process.


Ultrasound in Obstetrics & Gynecology | 2000

WS17‐06Three‐dimensional power Doppler ultrasound as a second line screening tool in ovarian cancer screening – preliminary results

T. Zodan; M. Gregov; V. Sparac; Asim Kurjak; Sanja Kupesic; M. Ilijas

Introduction


Ultrasound in Obstetrics & Gynecology | 2000

WS09‐06What does contrast media add to three dimensional power Doppler evaluation of adnexal masses?

V. Sparac; Sanja Kupesic; Asim Kurjak

Aim


Ultrasound in Obstetrics & Gynecology | 2000

Three‐dimensional ultrasonographic and power Doppler characterization of ovarian lesions

Asim Kurjak; Sanja Kupesic; V. Sparac; Dragutin Košuta


Ultrasound in Obstetrics & Gynecology | 1998

The assessment of ovarian tumor angiogenesis: what does three-dimensional power Doppler add?

Asim Kurjak; Sanja Kupesic; Branko Breyer; V. Sparac; Stanko Jukić


Gynecologic Oncology | 1998

Preoperative Diagnosis of Primary Fallopian Tube Carcinoma

Asim Kurjak; Sanja Kupesic; Marijan Ilijaš; V. Sparac; Dragutin Košuta


Croatian Medical Journal | 2005

Three-dimensional Ultrasonography and Power Doppler in Ovarian Cancer Screening of Asymptomatic Peri- and Postmenopausal Women

Asim Kurjak; Matija Prka; José Bajo Arenas; V. Sparac; Merce Lt; Ante Corušić; Mirjana Ivančić-Košuta

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