Vanessa B. Sheppard

Sentiment Analysis of an Online Breast Cancer Support Group: Communicating about Tamoxifen

ABSTRACT A better understanding of the breast cancer online narrative is important for a clearer conceptualizing of the role of online platforms in mediating health-related support. Sentiment analysis was conducted on a breast cancer online support group regarding Tamoxifen to understand users’ emotions and opinions. This analysis was then contextualized within online social support literature. Out of the 498 users, the most active users were 80% more positive than least active users, while least active users were 48% more negative than most active ones; both differences were statistically significant. The higher the stage of cancer a user had, the less likelihood that she would have posted, and if she were to post, the post would have focused on her side effects and the anxiety/sadness that tailgates those side effects. The lower the stage of cancer a user had, the more likelihood that she would have posted, additionally remained active on the forum, and encouraged more (online) social support. This finding suggests that the online support platform may provide a context that exacerbates support for like-minded users where stronger ties are created around a specific sentiment within the community with less connection from those with dissimilar sentiments to the dominant group.

Applying the Theory of Planned Behavior to Examine Adjuvant Endocrine Therapy Adherence Intentions

Adherence to adjuvant endocrine therapy (AET) in breast cancer survivors is suboptimal. Using the theory of planned behavior (TPB), this study aimed to identify the strongest predictors from the TPB of AET intentions and past behavior and assessed whether ambivalence and anticipatory emotions increased the predictive capacity of TPB.

Spirituality in African-American Breast Cancer Patients: Implications for Clinical and Psychosocial Care

Spirituality has been shown to be important to many individuals dealing with a cancer diagnosis. While African-American breast cancer survivors have been reported to have higher levels of spirituality compared to White women, little is known about how levels of spirituality may vary among African-American breast cancer survivors. The aims of this study were to examine factors associated with spirituality among African-American survivors and test whether spirituality levels were associated with women’s attitudes about treatment or health care. The primary outcome, spirituality, was nine-item scale (Cronbach’s α = .99). Participants completed standardized telephone interviews that captured sociocultural, healthcare process, and treatment attitudes. Medical records were abstracted post-adjuvant therapy for treatment and clinical information. In bivariate analysis, age was not correlated with spirituality (p = .40). Married/living as married women had higher levels of spirituality (m = 32.1) than single women (m = 30.1). Contextual factors that were associated with higher levels spirituality were: collectivism (r = .44; p < 0.0001, Afrocentric worldview (r = .185; p = .01), and self-efficacy scale (r = .17; p = .02). In multivariable analysis, sociodemographic factors were not significant. Collectivism remained a robust predictor (p < 0.0001). Attitudes about the efficacy of cancer treatment were not associated with spirituality. The high levels of spirituality in African-American survivors suggest consideration of integrating spiritual care within the delivery of cancer treatment. Future studies should consider how spirituality may contribute to positive coping and/or behaviors in African-American women with high levels of spirituality.

Medical Mistrust in Black Breast Cancer Patients: Acknowledging the Roles of the Trustor and the Trustee

Studies indicate that Black patients report higher medical mistrust compared to their White counterparts. However, little is known about factors associated with higher medical mistrust among Black breast cancer patients. We examined predictors of medical mistrust and relationships between medical mistrust, subscales of mistrust, and process of care factors to identify opportunities to promote positive healthcare interactions between the trustees (e.g., providers) and Black breast cancer patients, or the trustors. A secondary analysis was conducted of survey data from 210 Black women with confirmed diagnosis of invasive breast cancer. Participants completed telephone surveys consisting of questions pertaining to sociodemographics, attitudes, and beliefs about medical care and breast cancer treatments. Multiple linear regression determined factors associated with medical mistrust and mistrust subscales. Most participants (61%) were over the age of 50 and currently single (64.8%). Women with greater medical mistrust reported less satisfaction with the trustee’s technical ability (p < 0.0001) and greater satisfaction with their own propensity to access care (p < 0.05). Additionally, women with public insurance demonstrated greater mistrust (p < 0.01) and suspicion (p < 0.05) than women with private insurance, and women with less education reported greater perceived discrimination than women who have at least a bachelor’s degree. Findings from this study may inform future endeavors to educate providers on ways to effectively interact with and treat Black breast cancer patients. Opportunities to develop interventions that address and tackle issues of mistrust as reported by Black patients may contribute to ongoing efforts to reduce health disparities.

Initiation of Adjuvant Endocrine Therapy in Black and White Women With Breast Cancer

Background Adjuvant endocrine therapy reduces risk of recurrence and mortality in women with hormone receptor–positive breast cancer, yet many women never initiate it. We examined the influence of race, sociocultural factors, and process‐of‐care factors on initiation of adjuvant endocrine therapy in a racially diverse sample. Patients and Methods Eligible women were originally recruited for the Narrowing the Gaps in Adjuvant Therapy Study (2006‐2011). Sociocultural and process‐of‐care factors were collected via telephone surveys before adjuvant therapy. Clinical factors were abstracted from charts. Penalized LASSO (least absolute shrinkage and selection operator) logistic regression model was used to identify variables associated with initiation. Results Of the 270 women, 55.6% were black and the rest were white. Most women (74.8%) initiated therapy. A significant interaction (P = .008) was found between race and age. Black women aged ≤ 50 years had the lowest initiation (59.7%) compared to black women > 50 years (87.1%), white women ≤ 50 years (73.7%), or white women > 50 years (72.0%). Multivariate analysis found that younger black women exhibited a marginally higher risk of noninitiation compared to older black women. Additionally, ratings of financial access, presence of comorbidities, and levels of communication were all associated with endocrine therapy initiation. Conclusion Black women ≤ 50 years of age and women with financial constraints may be important subgroups for interventions. Patient–provider communication appears to be an important leverage point to foster therapy uptake. Micro‐Abstract Adjuvant endocrine therapy (AET) is recommended for women diagnosed with hormone receptor (HR) positive breast cancer. AET reduces breast cancer recurrence and morality. Black women have high rates of breast cancer morality and recent reports suggest that black women with HR positive disease have higher breast cancer mortality than white women with HR positive disease. Thus, initiation of AET may be particularly important for black women with HR positive breast cancer. Information about the impact of race on initiation of AET is limited and has been inconsistent. This study focused on 270 black (n = 150) and white (n = 120) women with HR positive breast cancer. We found that the initiation of chemotherapy was related to a combination of woman’s age and race rather than just her race alone. Black women (≤50 years old) had the lowest rate of AET initiaiton 59.7%. The proportional representation of Black and White women in our study may have aided our ability to examine differences within subgroups rather than just between Blacks and Whites which highlights the need for diverse study samples.