Veena G Kamath

A study on the prevalence of type 2 diabetes in coastal Karnataka

Aim: To estimate the prevalence and study the socio-demographic correlates of type 2 diabetes among adults aged 30 years and above. Setting and Design: A cross-sectional community-based survey, among individuals of either sex, aged 30 years and above was carried out in the field practice area of a medical college. Methods and Materials: The study was carried out on 1,239 respondents, using a two-stage, stratified, random sampling technique. Data was collected by a personal, face-to-face interview followed by blood sugar estimation using a glucometer. Statistical Analysis: Was performed by using the Statistical Package for Social Sciences (SPSS) version 11.5. Results: The overall prevalence of diabetes was 16%. Self-reported diabetes was 11.2%, while 4.8% of previously normal people were found to have high fasting capillary blood glucose levels. Increasing age showed two-fold, four-fold, and six-fold higher odds for 40 – 49, 50 – 59, and ≥ 60 years age group, respectively, as compared to the 30 - 39 year age group (P < 0.001). Nineteen percent of the males had diabetes, (OR = 1.38, 95% CI = 1.01 – 1.88). In the high socioeconomic strata, 32% of the subjects had diabetes (P = 0.018 unadjusted odds ratio 3.29, 95% CI = 1.40 – 7.74). Conclusion: The high prevalence of diabetes in this coastal population needs further evaluation.

High Blood Pressure Prevalence and Significant Correlates: A Quantitative Analysis from Coastal Karnataka, India

Hypertension is a premier risk factor for cardiovascular disease which can be recognized if sought and treated effectively. Effective management of high blood pressure is possible when the magnitude of the problem is identified. So, a cross-sectional community based survey among 1,239 respondents aged ≥30 years was designed to estimate the prevalence and the sociodemographic correlates of hypertension among adults aged ≥30 years. Data was collected by personal interviews, followed by anthropometric and blood pressure measurements. Analysis was done using Statistical Package for the Social Sciences (SPSS) version 11.5. The prevalence of hypertension was 43.3%, with the prevalence being more among males (51.6%) as compared to females (38.9%). Of the total prevalence 23.1% (287) were known cases, and 20.2% (250) were newly detected cases. Based on the seventh report of the Joint National Committee (JNC VII) on high blood pressure, prehypertension was noted among 38.7%. Advancing age, male gender, current diabetic status, central obesity, overweight and obesity as defined by body mass index, and family history of hypertension were identified as significant correlates for hypertension by multivariate logistic regression.

A cross-sectional analysis of obesity among a rural population in coastal Southern Karnataka, India

BACKGROUND Obesity is a disease condition that is highly prevalent in both developed and developing countries. Obesity accounts for 60% of cases of diabetes, 40% cases of hypertension and 20% of coronary heart disease and stroke. Although obesity is a silent killer in the third world countries, there is less focus on the problem, as the nations are still staggering with problems due to infectious and parasitic diseases. So, the current study was undertaken to highlight the problem. METHOD A cross-sectional community based survey, among individuals of either sex, aged 30 years and above was carried out on 1,239 respondents, using a two-stage stratified, random sampling technique. Data was collected by personal face to face interview using a pre-designed questionnaire and analyzed using Statistical Package for Social Sciences (SPSS) version 11.5. RESULTS The overweight category included 21.4% of the subjects. Obesity as per Body Mass Index (BMI) criteria was seen in 6.6% of the individuals but abdominal and truncal obesity was present among 51.7% and 62.1% respectively. Literacy up to secondary education and graduation were identified by the multivariate analysis to be associated with obesity. CONCLUSION The prevalence of central obesity was found to be high, and hence, lifestyle changes and improved physical activity needs promotion among the general population.

Detection of genital HPV infection using urine samples: a population based study in India

BACKGROUND Cervical cancer is the second commonest cancer among Indian women and its association with human papilloma virus (HPV) is well established. This preventable cancer accounts for the maximum number of cancer related deaths among rural Indian women. Unlike in developed countries there are no organized cervical cancer screening programmes in India due to lack of resources and manpower. OBJECTIVE To detect genital HPV infection using urine samples among asymptomatic rural women in the age group of 18-65 years. MATERIALS AND METHODS The study area chosen was Perdoor village in Udupi Taluk, Karnataka State and all the women in the age group of 18-65 years formed the study cohort. A cross sectional study was conducted by house visits and 1,305 women were enrolled in the study. After taking written informed consent a data sheet was filled and early stream random urine samples were collected, transported to a laboratory at 4OC and aliquoted. Samples were tested using nested HPV PCR with PGMY09/11 and GP5+/6+ primers. Positive cases were genotyped by sequence analysis. RESULTS Study participants included 1,134 sexually active and 171 unmarried women with a mean age at marriage of 22.1 (SD=3.9) years. Study area showed high female literacy rate of 86.6%. Five urine samples tested positive for HPV DNA (0.4%). CONCLUSIONS We found very low genital HPV infection rate among women from monogamous community. This is the first major population based study carried out among asymptomatic rural women to detect genital HPV infectio from Karnataka using urine samples.

Knowledge, Attitude and Practice Concerning Human Papilloma Virus Infection and its Health Effects among Rural Women, Karnataka, South India

BACKGROUND Cervical cancer is one of the commonest cancers among women all over the world. The association of cervical cancer with human papilloma virus (HPV) is well established. Knowledge about the causal relationship between HPV and cervical cancer is important to make appropriate, evidence-based health care choices. In this context we conducted a community based study among women about the knowledge, attitude and practice about HPV infections and their health effects. MATERIALS AND METHODS A cross sectional interview based house to house survey was conducted with a validated data collection tool covering sociodemographic factors, knowledge, attitude and practice about HPV and its health effects, among 1020 women from a rural village, Perdoor, in Udupi district, Karnataka, India in 2013-14. RESULTS The mean age of participants was 38.9 years (SD=12.6). Study participants showed a high literacy rate (85.7%). Only 2.4% of sexually exposed women had undergone Pap smear testing. Partners of 4.4%women had undergone circumcision and they belonged to the Muslim community. Male condom usage was reported by 26 women (2.6%). However, none of the participants had heard of HPV and its health effects. CONCLUSIONS This community based study found complete ignorance about HPV among rural South Indian women in spite of a high literacy level.

Nutritional status assessment of under -five beneficiaries of Integrated Child Development Services program in rural Karnataka

Background The prevalence of underweight children in India is among the highest in the world, and is nearly double that of Sub- Saharan Africa. The effect of malnutrition is high morbidit and mortality among young children. The objective of this study was to determine the nutritional status of children aged between 3-6 years registered in government sponsored maternal and child care Anganwadi centres in India. Method A cross-sectional study was conducted in 35 centres in 11 villages situated in the field practice area of Community Medicine Department of a Medical College situated in Southern India. Results Of the 585 children in the study, 46.5% of the children were aged between 36 to 48 months. Assessment of nutritional status using the ICDS growth chart revealed malnourishment to be present among 189 (32.3%) children, of whom 166 children were grade I malnourished and 23 children were grade II malnourished. Proportionally girls (46.2%) were more malnourished than boys (33.6%). No significant association was found between the nutritional status of children and their duration of stay in an Anganwadi centre (p-value=0.56).Conclusion The findings of this study indicate that malnutrition is still an important problem even among children attending Anganwadis. Further improvements in functioning of Integrated Child Development Services need to be made in order to address the problem of malnutrition

Effectiveness of a training program for bleeding disorders among accredited social health activists in Udupi District, Karnataka, India

Hemophilia and other bleeding disorders are underreported and cause significant morbidity and mortality in resource‐constrained countries. Training and the creation of awareness among accredited social heath activists (ASHAs) will aid in the early detection of bleeding disorders at the community level.

Global human papilloma virus vaccine implementation: An update

Human papillomavirus (HPV) infections continue to be one of the most common sexually transmitted infections worldwide. The oncogenic potential of this virus was well established in anogenital malignancies and oropharyngeal cancers. Even though a fall in cervical cancer rates has been reported worldwide, the subsequent rise in HPV‐associated head and neck cancers among men and women have been reported from developed countries, necessitating the vaccination of adolescent boys as well. The objective of this narrative review is to provide an update on the current status of HPV vaccination worldwide. This will be helpful for clinicians in counseling parents and guardians as this vaccine mainly targets sexually naïve preadolescents. An electronic search of the databases was carried out to retrieve information concerning HPV vaccine implementation between July 2006 and 2017, with special emphasis on the current viewpoints, controversies and ethical issues. Globally, 74 countries have implemented the HPV vaccine in the national immunization schedule, and this vaccine is listed as an essential medicine by WHO. About 60% of the low‐ and lower–middle‐income countries have implemented the vaccine with financial assistance from Gavi and WHO. The HPV vaccine is a safe vaccine with no serious adverse effects as per the data available from developed nations as well as low/lower middle/upper middle‐income countries. However, long‐term follow‐up is essential to substantiate the impact of the vaccination programs in cancer prevention.

Community-based prevalence of genital human papilloma virus (HPV) infection: A systematic review and meta-analysis

Introduction: Cervical cancer probably represents the best-studied human cancer caused by a viral infection and the causal association of this preventable cancer with human papilloma virus (HPV) is well established. Worldwide there is a scarcity of data regarding HPV prevalence with vast differences existing among populations. Objective: The aim of this meta-analysis was to determine the community-based HPV prevalence estimates among asymptomatic women from urban and rural set ups and in participants of cancer screening clinics. Study design: Systematic review and meta-analysis. Methods: PubMed-Medline, CINAHL, Scopus, and Google scholar were systematically searched for studies providing prevalence data for HPV infection among asymptomatic women between 1986 and 2016. Results: The final analysis included 32 studies comprising a population of 224,320 asymptomatic women. The overall pooled HPV prevalence was 11% (95% confidence interval (CI), 9%-12%). The pooled HPV prevalence of 11% (95% CI, 9%-11%) was observed among women attending cervical cancer screening clinics. The pooled HPV prevalences were 10% (95% CI 8%-12%) and 11% (95% CI 4%-18%) from urban and rural areas respectively, indicating higher infection rates among the rural women with the least access to cancer screening and cancer care. Conclusion: The prevalence rates in this systematic quantitative review provide a reliable estimate of the burden of HPV infection among asymptomatic women from developed as well as developing nations. Rural women and women attending cervical cancer screening programmes feature higher genital HPV prevalences compared to their urban counterparts.

Prevalence of Pelvic Floor Dysfunction among Married Women of UdupiTaluk, Karnataka, India

Background: Pelvic floor dysfunction predominantly affects women of all the ages with an increasing prevalence with advancing age. Very few studies on prevalence of urinary incontinence have been conducted in India and none in Udupi taluk. Aim: The aim of this cross-sectional study is to estimate the prevalence of Pelvic Floor Dysfunction among married women of Udupi taluk, Karnataka, India and to evaluate the impact of age, educational qualification, occupation, parity and mode of delivery on pelvic floor dysfunction. Materials and Methods: A cross-sectional study was conducted on 1256 married women using a structured questionnaire. Women were interviewed at their residence using the questionnaire. Institutional ethical committee approval and written informed consent was obtained before the interview. Result: Prevalence of pelvic floor dysfunction was reported to be 21% with 19.02% of the women experiencing urinary incontinence and 1.99% experiencing pelvic organ prolapse. The mean age of the women participated in this study was 45.4 ± 11.8 (ranging between 18-70 years). Eighty seven percent of the women were housewives and 69% of the women had only primary education. Statistically significant association was found between age (p ≤ 0.001), occupation of the women (p ≤ 0.001), presence of urinary incontinence during pregnancy which disappeared after delivery (p=0.009) and occurrence of at least one type of pelvic floor dysfunction. Age, occupation and presence of symptom of urinary incontinence during pregnancy which disappeared after the delivery were reported as the independent predictor of symptoms of pelvic floor dysfunction when analyzed with multivariate logistic regression model. Conclusion: Prevalence of pelvic floor dysfunction among women of Udupi Taluk, Karnataka, India was found to be 21% with age, occupation and presence of symptom of urinary incontinence during pregnancy which disappeared after the delivery as the independent predictor of symptoms of pelvic floor dysfunction.