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Dive into the research topics where Verónica Piera is active.

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Featured researches published by Verónica Piera.


British Journal of Obstetrics and Gynaecology | 1999

Tissue factor levels and high ratio of fibrinopeptide A:D-dimer as a measure of endothelial procoagulant disorder in pre-eclampsia

Jordi Bellart; Rosa Gilabert; Anna Anglès; Verónica Piera; Ramón M. Miralles; Jasone Monasterio; L. Cabero

To assess coagulation activation and endothelial cell injury in normotensive and pre‐eclamptic pregnant women, a comparision was made of plama levels of tissue factor, fibronectin, fibrinopeptide A and D‐dimer. Samples were taken from 50 nonpregnant women, 40 normotensive pregnant women in the third trimester and 27 women with pre‐eclampsia after diagnosis and before treatment. High levels of fibrinopeptide A and D‐dimer were found in pre‐eclampsia women. Moreover, the ratio fibrinopeptide A:D‐dimer was much greater in the pre‐eclampsia group than in normotensive pregnant women. The levels of fibronectin and tissue factor were also higher in the pre‐eclampsia group. The increase of tissue factor levels suggests an alteration of the extrinsir coagulation pathway in pre‐eclampsia. The increase of fibrinopeptide A:D dimer ratio shows that the activation of coagulation is associated with a relative hypofibrinolysis in pre‐eclampsia.


Bioelectromagnetics | 1997

HISTOLOGICAL CHANGES DURING DEVELOPMENT OF THE CEREBELLUM IN THE CHICK EMBRYO EXPOSED TO A STATIC MAGNETIC FIELD

Auxiliadora Espinar; Verónica Piera; A. Carmona; Juan M. Guerrero

Few studies have been performed to evaluate the ultrastructural changes that exposure to static magnetic fields (SMF) can cause to the processes of cell migration and differentiation in the cerebellum during development. Thus, we have studied the development of the cerebellum in the chick embryo (n = 144) under a uniform SMF (20 mT). All of our observations were done on folium VIc of Larsells classification. The cerebella of chick embryos, which were exposed solely on day 6 of incubation and sacrificed at day 13 of incubation [short exposure (S)1; n = 24], showed an external granular layer (EGL) that was less dense than the EGL in the control group (n = 24). The molecular layer (ML) exhibited a low number of migratory neuroblastic elements. Moreover, the internal granular layer (IGL) was immature, with the cellular elements less abundant and more dispersed than in controls. In chick embryos exposed on day 6 of incubation and sacrificed at day 17 (S2; n = 24), the outstanding feature was the regeneration of the different layers of the cerebellar cortex. The cerebellar cortex of chick embryos exposed continuously to an identical field from the beginning of the incubation up to day 13 [long exposure (L)1; n = 24] or day 17 (L2; n = 24) of incubation showed a higher number of alterations than that of group S1. Electron microscopy confirmed the findings from light microscopy and, at the same time, showed clear signs of cell degeneration and delay in the process of neuronal differentiation. This was more apparent in groups L1 (100%) and L2 (100%) than in groups S1 (95.4%) and S2 (65.2%). In conclusion, the present study showed that SMF can induce irreversible developmental effects on the processes of cell migration and differentiation of the chick cerebellar cortex.


Craniomaxillofacial Trauma and Reconstruction | 2009

Extended Transcaruncular Approach Using Detachment and Repositioning of the Inferior Oblique Muscle for the Traumatic Repair of the Medial Orbital Wall

Javier Rodriguez; Ramón Galán; Gabriel Forteza; Mario Mateos; Jens Mommsen; Olga Vázquez Bouso; Verónica Piera

The fracture of the medial orbital wall is relatively common in orbital trauma. Titanium mesh is possibly the actual standard material for orbital wall reconstruction. When the floor of the orbit and the medial wall are simultaneously affected, one larger mesh gives better results than two independent meshes that need to be fixated independently. However, large meshes need a wider surgical field. To gain sufficient exposure to the medial and inferior orbital walls simultaneously, we present an approach that combines the transconjunctival and transcaruncular incisions, detaching if needed the inferior oblique muscle and, placing our mesh, repositioning it beside the lacrimal duct. This technique should not entirely displace traditional approaches, but it widens the surgical exposure for middle- and upper-third facial trauma. This alternative has minimum morbidity and can save a great deal of surgery time.


Gynecologic and Obstetric Investigation | 1999

Endothelial Cell Lesion in Preeclampsia

Rosa Gilabert; Jordi Bellart; Montserrat Jové; Ramón M. Miralles; Verónica Piera

Morphofunctional study of umbilical cords from pregnancies complicated by preeclampsia shows both activation and lesion of endothelium. The cellular findings in umbilical cords from pregnancies complicated by preeclampsia can be summarized as: (i) higher number of cells with secretion bladders and increase in the number and size of both secretion bladders and microvilli-like protrusions; (ii) increase in collagen, fibrin, fibronectin and lipidic vesicles in the vessel wall; (iii) vacuolization of endothelial cells; (iv) presence of lipidic vacuoles and lipophages in the vessel wall; (v) erosion and disorganisation of the endothelium that exposes extracellular proteins to the blood flow. Endothelial cell cultures from preeclamptic pregnancies show kinetic disorders and cell detachment. The results confirm that an endothelial cell lesion occurs in preeclampsia and this cellular disorder can be reproduced in vitro.


Cells Tissues Organs | 1992

Influence of continuous electromagnetic fields on the stage, weight and stature of the chick embryo.

Verónica Piera; A. Rodriguez; A. Cobos; Miguel Torrente; Pedro Cobos

The influence of continuous electromagnetic fields (0, 181 or 361 Gs/cm2) on the development of chick embryo (n = 144) was studied. Several parameters were determined at days 5, 10 and 15 of incubation: stage (following Hamburger and Hamilton), vertex-coccyx length (size) and weight. At 5 days of incubation, all embryos showed a similar stage. However, at days 10 and 15, the embryos exposed to 181 Gs/cm2 showed a stage significantly superior to that of the others. There were no differences between the exposed embryos and the control ones with regard to weight and stature, except at 15 days when the embryos exposed to 361 Gs/cm2 showed greater weight and stature than those of the controls.


Cells Tissues Organs | 1999

Effects of Static Electromagnetic Fields on Chick Embryo Pineal Gland Development

Montserrat Jové; Miguel Torrente; Rosa Gilabert; Auxiliadora Espinar; Pedro Cobos; Verónica Piera

The effects of static electromagnetic fields on the development of the chick embryo pineal gland were studied. A total of 144 fertilized White Leghorn eggs were sacrificed after 5, 10 and 15 days of incubation. The stage of development was determined in all embryos using the Hamburger and Hamilton method [J Morphol 49: 88–92, 1951]. The various morphometric parameters (diameter and distance of the pineal gland and its lumen) were measured on serial 7-μm-thick sections. The data were obtained in a morphometer and processed statistically. The intensities of the static electromagnetic fields were 18 and 36 mT. Control and exposed embryos were equally distributed and randomly assigned. After 5 days of incubation, 25% of embryos exposed to a static electromagnetic field of 18 mT had a more advanced stage of development than controls and embryos exposed to 36 mT. On the 10th and 15th day, embryos exposed to either 18 or 36 mT tended to be more developed than controls. In the morphometric study, results were similar for the controls and exposed embryos after 5 and 10 days of incubation. However, the values of the 15-day-old embryos exposed to static magnetic fields were lower than the values of the controls (p > 0.01). These differences were more pronounced in the embryos exposed to 36 mT. These results seem to indicate that static electromagnetic fields affect the development and growth of embryos unequally, and that their action can depend not only on the intensity of the static electromagnetic field, but also on the length of exposure and the organ which is developing. It may be interesting to use these data in ultrastructural and physiological studies.


Cirugia Espanola | 2009

Colgajo de cresta ilíaca de doble pedículo vascular

Javier Rodríguez Fernández; Mario Mateos Micas; Ramón Galán; Pedro Cobos; Margarita Jové; Laura Aguilera; Olga Vázquez; Jens Mommsen; Gabriel Forteza; Verónica Piera

Resumen Introduccion El colgajo de cresta iliaca (CCI) es uno de los utilizados con mayor frecuencia en la reconstruccion facial. Su vascularizacion depende de los vasos circunflejos iliacos profundos (ACIP, VCIP). Este trabajo describe, por primera vez, la posibilidad de doble irrigacion de la isla cutanea del CCI incluyendo el sistema circunflejo iliaco superficial para la reconstruccion de cabeza y cuello. Material y metodo Se diseccionaron 10 regiones inguinales de 5 cadaveres en el Departamento de Anatomia de la Facultad de Medicina Rovira i Virgili de Reus (Tarragona). En el periodo 2005-2007, 3 pacientes fueron intervenidos en el Servicio de Cirugia Maxilofacial del Hospital Joan XXIII de Tarragona, requiriendo un colgajo osteomiocutaneo microvascularizado de cresta iliaca. Resultados Los 3 casos clinicos mostraron una evolucion satisfactoria. Esta tecnica proporciona una mayor vascularizacion del colgajo y una mayor disponibilidad tridimensional e implica menor morbilidad de la zona donante, ya que se necesita tallar menos cantidad de oblicuo pues la irrigacion de los vasos perforantes no depende de la ACIP. Conclusiones Esta variacion tecnica del colgajo de cresta iliaca puede sernos de gran utilidad en la reconstruccion de defectos complejos maxilofaciales a cambio de realizar una diseccion vascular y su anastomosis extra.


Cirugia Espanola | 2009

Double vascular pedicle iliac crest flap

Javier Rodríguez Fernández; Mario Mateos Micas; Ramón Galán; Pedro Cobos; Margarita Jové; Laura Aguilera; Olga Vázquez; Jens Mommsen; Gabriel Forteza; Verónica Piera

Abstract Introduction The iliac crest flap is commonly used in reconstructions of the head and neck. The vascularisation of this region depends on the deep circumflex iliac artery and vein (ACIP/VCIP).The present study describes for the first time, the simultaneous use of the deep and superficial circumflex iliac systems to obtain an iliac crest flap for head and neck reconstructions. Material and method Ten inguinal regions were dissected in 5 cadavers in the Human Anatomy and Embryology Unit of the Faculty of Medicine of the Rovira i Virgili University (Reus, Spain). In the period 2005–2007, 3 patients required mandibular reconstruction with a microvascularised iliac crest osteocutaneous flap at the Maxillofacial Surgery Unit of the Joan XXIII University Hospital (Tarragona, Spain). Results The 3 cases showed a favourable outcome. This “supercharging” variation guarantees the perfusion to the skin flap, provides a better3-dimensional arrangement of the soft tissue and lowers the morbidity at the donor site, as much less internal oblique muscle cuff is harvested Conclusions This technique may be of great interest in the reconstruction of complex maxillofacial defects instead of having to carry out a vascular dissection and its extra anastomosis.


European Journal of Morphology | 1999

Embryonic development of pineal gland vesicles: a morphological and morphometrical study in chick embryos.

Montserrat Jové; Pedro Cobos; Miguel Torrente; Rosa Gilabert; Verónica Piera


MedEdPublish | 2017

PRE-CLINICAL SKILLS: A competency-based assessment integrated course implemented early in the curriculum to prepare second-year medical students prior to entering clinical settings

Maria Rosa Fenoll-Brunet; Verónica Piera; Domènec Sánchez; Maria A. Lanuza; Neus Garcia; Pedro Cobos

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Rosa Gilabert

Rovira i Virgili University

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Jordi Bellart

Rovira i Virgili University

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Ramón M. Miralles

Rovira i Virgili University

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A. Cobos

University of Barcelona

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A. Rodriguez

University of Barcelona

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Anna Anglès

Autonomous University of Barcelona

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Jasone Monasterio

Autonomous University of Barcelona

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