Is this you? Create Your Porfile
Avatar

Veronique Birault

Janssen Pharmaceutica

Network

Latest external collaboration on country level. Dive into details by clicking on the dots.

Explore More

Hotspot

Dive into the research topics where Veronique Birault is active.

Explore More

Publication

Featured researches published by Veronique Birault.

Bioorganic & Medicinal Chemistry Letters | 2012

Discovery of a series of imidazopyrazine small molecule inhibitors of the kinase MAPKAPK5, that show activity using in vitro and in vivo models of rheumatoid arthritis

Martin James Inglis Andrews; J. Andrew Clase; Grégory Louis Joseph Bar; Giovanni Alessandro Tricarico; Paul John Edwards; Reginald Brys; Mark Stuart Chambers; Wolfgang Schmidt; Angus Murray Macleod; Kim Louise Hirst; Vivienne Allen; Veronique Birault; Joelle Le; John T. Harris; Andrew Self; Kevin Nash; Graham Dixon

MAPKAPK5 has been proposed to play a role in regulation of matrix metalloprotease expression and so to be a potential target for intervention in rheumatoid arthritis. We present here the identification of a series of compounds against this target which are effective in both biochemical and cell assays. The expansion of the series is described, along with early SAR and pharmacokinetics for some representative compounds.

Archive | 2006

Compounds Which Bind to the Active Site of Protein Kinase Enzymes

Veronique Birault; Clifford John Harris; Roger Crossley

Archive | 2007

Imidazolopyrazine compounds useful for the treatment of degenerative and inflammatory diseases

Martin James Inglis Andrews; Paul Edwards; Reginald Christophe Xavier Brys; Philip Huxley; Wolfgang Schmidt; Veronique Birault; Mark Stuart Chambers; Clifford John Harris; Angus Macleod; Kim Louise Hirst; Juha Andrew Clase; Gregory Bar

Archive | 2005

Imidazo ‘1,2-a’ pyrazine compounds which interact with protein kinases

Veronique Birault; Clifford John Harris; Stephen Harrison

Archive | 2012

Sulfonamide compounds and their use in the modulation retinoid - related orphan receptor

Veronique Birault; Amanda Jennifer Campbell; Stephen Harrison; Joelle Le

Archive | 2012

Composés de sulfonamide et leur utilisation dans la modulation du récepteur orphelin apparenté au récepteur des rétinoïdes

Veronique Birault; Amanda Jennifer Campbell; Stephen Harrison; Joelle Le

Archive | 2007

Triazolopyrazinverbindungen for treatment of degenerative and inflammatory diseases

Andrew Burritt; Paul John Edwards; Wolfgang Schmidt; Veronique Birault; Friedrich Erich Karl Kroll; Xueliang Tao; Martin James Inglis Andrews; Sebastien Laurent Xavier Martina

Archive | 2007

Triazolopyrazinverbindungen zur behandlung von degenerations- und entzündungskrankheiten Triazolopyrazinverbindungen for treatment of degenerative diseases and inflammatory

Andrew Burritt; Paul John Edwards; Wolfgang Schmidt; Veronique Birault; Friedrich Erich Karl Kroll; Xueliang Tao; Martin James Inglis Andrews; Sebastien Laurent Xavier Martina

Archive | 2007

Composés d'imidazolopyrazine utiles pour le traitement des maladies dégénératives et inflammatoires

Reginald Brys; Paul John Edwards; Wolfgang Schmidt; Martin James Inglis Andrews; Mark Stuart Chambers; Juha Andrew Clase; Veronique Birault; Kim Louise Hirst; Angus Murray Macleod; Grégory Louis Joseph Bar; Clifford John Harris; Philip Huxley

Archive | 2005

Composes de 1,2-a' pyrazine imidazo interagissant avec les proteines kinases

Veronique Birault; Clifford John Harris; Stephen Harrison

Explore More

Collaboration

Dive into the Veronique Birault's collaboration.

Top Co-Authors
Avatar

Clifford John Harris

Janssen Pharmaceutica

View shared research outputs
Top Co-Authors
Avatar

Martin James Inglis Andrews

Galápagos NV

View shared research outputs
Top Co-Authors
Avatar

Paul John Edwards

Galápagos NV

View shared research outputs
Top Co-Authors
Avatar

Wolfgang Schmidt

Aventis Pharma

View shared research outputs
Top Co-Authors
Avatar

Kim Louise Hirst

Janssen Pharmaceutica

View shared research outputs
Top Co-Authors
Avatar

Joelle Le

Bayer HealthCare Pharmaceuticals

View shared research outputs
Top Co-Authors
Avatar

Andrew Burritt

Galápagos NV

View shared research outputs
Top Co-Authors
Avatar

Friedrich Erich Karl Kroll

Galápagos NV

View shared research outputs
Top Co-Authors
Avatar

Grégory Louis Joseph Bar

Galápagos NV

View shared research outputs
Top Co-Authors
Avatar

Juha Andrew Clase

Janssen Pharmaceutica

View shared research outputs
Explore More
Researchain Logo
Decentralizing Knowledge