Vesna Tomic-Spiric
University of Belgrade
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Publication
Featured researches published by Vesna Tomic-Spiric.
Clinical Respiratory Journal | 2014
Dragica Pesut; Sanvila Raskovic; Vesna Tomic-Spiric; Milica Bulajic; Mirjana Bogic; Bogdana Bursuc
The increasing prevalence of allergic rhinitis (AR) is reported worldwide. Illness perception (IP) assessment is warranted in current routine clinical practice to assist communication between patients and medical staff, and improve adherence to treatment and disease outcome.
Central European Journal of Medicine | 2010
Slavenka Janković; Natasa Maksimovic; Janko Janković; Milena Ražnatović; Jelena Marinkovic; Vesna Tomic-Spiric
The aim of the present case-control study was to assess the risk factors for Basal cell carcinoma (BCC) in the Montenegrin population. The study group was comprised of 100 consecutive patients with a diagnosis of BCC, while the control group consisted of patients who did not present skin cancer and who were individually matched to the cases by sex and age. The increased risk for BCC was associated with: the presence of nevi (odds ratio [OR] = 3.77; 95% confidence interval [CI] = 1.12–12.73), type of skin concerning to burn rather than to tan after repeated sun exposure in childhood or adolescence (OR = 3.14; 95% CI = 1.59–6.18), the skin reaction to burn after two or more hours of sunlight during childhood or adolescence (OR = 4.53; 95% CI = 2.37–8.63), the number of severe and painful sunburns during their lifetime(OR = 3.52; 95% CI = 1.68–7.38), outdoor work during the summer-time (OR = 2.73; 95% CI = 1.00–7.45), occupational exposure to chemicals (OR = 17.89; 95% CI = 2.82–113.52), history of eczema (OR = 4.17; 95% CI = 1.53–11.39), and history of previous BCC (OR = 3.86; 95% CI = 1.40–10.65). Our study confirms the role of environmental and constitutional factors in development of BCC.
Military Medical and Pharmaceutical Journal of Serbia | 2017
Jasna Bolpacic; Nevena Savic; Snezana Arandjelovic; Vesna Tomic-Spiric; Sanvila Raskovic
Introduction. Wegeners’s granulomatosis is a disease characterized by granulomatous inflammation of the upper and/or lower respiratory tract, glomerulonephritis with varying degrees of small vessel vasculitis and classic anti-neutrophil cytoplasmic antibodies (c-ANCA) findings. The treatment uses different modalities of immunosuppressive therapy which does not always lead to remission. We presented the efficacy of biological therapy in a patient with refractory form of the Wegeners’s granulomatosis. Case report. A 23-years-old patient, was treated in August, 2011 at the Clinic of Otorhinolaryngology and Maxillofacial Surgery of the Clinical Center of Serbia because of suppurative otitis media, resulting twice in mastoidectomy. On the day 7 after the surgery, hemoptysis and fever occurred. Considering lung x-ray that showed presence of the round soft-tissue changes on both sides, nonspecific inflammatory syndrome in laboratory analysis and positive c-ANCA (1 : 160) with high titers the antibodies to the proteinase 3 (anti-PR 3), Wegeners granulomatosis was diagnosed. Due to the fact that administration of glucocorticoids, cyclophosphamide and immunomodulatory dose of immunoglobulin did not lead to clinical remission, it was decided to apply rituximab. After its application clinical remission occurred and it lasted fifteen months. Conclusion. Application of biologic therapy might be successful in the treatment of patients with severe form of refractory granulomatosis with polyangiitis.
Medicinski Pregled | 2012
Sanvila Raskovic; Jasna Bolpacic; Vesna Tomic-Spiric; Ljiljana Stefanovic; Mirjana Bogic
INTRODUCTION Polymiositis belongs to the group of inflammatory myopathies which are manifested by muscle weakness of the shoulder blade and pelvic region. The presence of typical skin manifestations is suggestive of dermatomyositis. These patients may also develop dysphagia (10-54%) as a result of involvement of the oropharyngeal and upper oesophageal striated muscles. Dermatomyositis may also be associated with another systemic disease or malignancy. CASE REPORT Hereby is presented the case of a 42-year-old female patient hospitalized at the Department of Allergy and Immunology, Clinical Center of Serbia for the shoulder blade and pelvic muscle weakness and pains in the small and large joints, eyelid edema, facial and neckline redness, difficult swallowing and loss of body mass. Based on the presence of proximal muscle weakness, increased enzyme serum levels (lactic acid dehydrogenase, glutamic-oxalacetic transaminase), positive electroneuromyography findings, typical skin changes and positive muscle biopsy, the patient was diagnosed to have dermatomyositis. Both radioscopy and esophagography revealed some disturbances in all phases of swallowing, absence of all primary and secondary peristaltic waves accompanied by contrast medium aspiration. Additionally, esophageal manometry proved the absence of esophageal peristalsis. Additional examinations ruled out the presence of any malignancies. The patient underwent glycocorticoid and azatioprim treatment along with specific dietary regimen, symptomatic and physical therapy, which led to favorable clinical outcome. CONCLUSION Dermatomyositis-associated dysphagia may lead to severe complications such as cachexia and aspiration pneumonia. In addition to the management of underlying disease, the treatment includes special dietary regimen, rehabilitation and even interventional surgical procedures, if necessary.
Journal of Cutaneous Medicine and Surgery | 2011
Slavenka Janković; Milena Raznatovic; Jelena Marinkovic; Janko Janković; Nikola Kocev; Vesna Tomic-Spiric; Nadja Vasiljevic
Srpski Arhiv Za Celokupno Lekarstvo | 2005
Natasa Maksimovic; M Slavenka Jankovic; Vesna Tomic-Spiric; M Jelena Marinkovic
Journal of Infection in Developing Countries | 2017
Snezana Arandjelovic; Branka Bonaci-Nikolic; Vesna Tomic-Spiric; Jasna Bolpacic; Sanvila Raskovic; Sladjana Andrejevic
Vojnosanitetski Pregled | 2015
Aleksandra Aleksic; Radoslav Gajanin; Dejan Djurdjevic; Zorica Novakovic; Dalibor Vranjes; Slobodan Spremo; Dmitar Travar; Natasa Guzina-Golac; Vesna Tomic-Spiric
Srpski Arhiv Za Celokupno Lekarstvo | 2015
Aleksandra Aleksic; Mirjana Bogic; Vesna Tomic-Spiric; Dalibor Vranjes; Borut Bosančić
Archive | 2015
Aleksandra Aleksic; Radoslav Gajanin; Dalibor Vranjes; Slobodan Spremo; Dmitar Travar; Vesna Tomic-Spiric