Victor W. Sidel

A generalization of the simple capture-recapture model with applications to epidemiological research☆

Abstract A method has been described to estimate the efficiency of each notification source and the total population when two or more independent sources are used for reporting the occurrence of events. The method depends on the independence of the sources and, for the special case of two sources, reduces to the simple capture-recapture model.

Models for the evaluation of pre-hospital coronary care.

Abstract A model is presented for the application of decision technics to the evaluation of alternative methods for pre-hospital care of heart attack. Such a model forces critical examination of goals and of all feasible methods for achieving these goals, and requires comparison of costs with benefits or effectiveness. Using the limited data available, this analysis suggests that if heart attack mortality in the population is to be substantially reduced, strategies of pre-coronary care are required which (1) would provide greater specificity in the identification of the person who is at high risk of sudden death due to heart attack and (2) would intercept the victim at the earliest feasible phase of the potentially fatal illness. As these strategies are developed, collection of further relevant data and application of the evaluation technics discussed will permit rational choice among the alternative methods.

LATE CLINICAL AND LABORATORY MANIFESTATIONS OF THOROTRAST ADMINISTRATION IN CEREBRAL ARTERIOGRAPHY: A FOLLOW-UP STUDY OF THIRTY PATIENTS.

Abstract Thirty patients who received thorotrast for cerebral arteriography from 1948 to 1952 were studied to determine the delayed effects of chronic low-dose internal-emitter radiation. The whole...

A follow-up study of a group of patients who received thorium dioxide for cerebral arteriography.

Human data on the effects of chronic low-dose internal-emitter radiation are limited. Most information, until this time, has been provided by study of radium dial painters (1). This paper, a study of patients who received Thorotrast, describes another source of information. Following the introduction of a commercially available product named Thorotrast in 1930, it became an important contrast material until the late 1940s. While it was used primarily by injection for hepatolienography and cerebral and peripheral arteriography, it was also employed for opacification of the nasal sinuses, retrograde pyelography, mammography, hysterosalpingography, seminal vesiculography, and sinus tract identification. Thorotrast fell into disrepute because of the severe localized fibrotic reaction it incited if extravasation occurred at the site of injection with resulting thorotrastoma and because of the increasing knowledge of the hazards of chronic, low-dose, alpha radiation (2). Thorotrast is a colloidal solution cont...