Vincenzo Camisa
Boston Children's Hospital
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Publication
Featured researches published by Vincenzo Camisa.
Photochemistry and Photobiology | 2012
Salvatore Zaffina; Vincenzo Camisa; Marco Lembo; Maria Vinci; Mario Graziano Tucci; Massimo Borra; Antonio Napolitano; Vittorio Cannatà
Ultraviolet radiation is known to cause both benefits and harmful effects on humans. The adverse effects mainly involve two target organs, skin and eye, and can be further divided into short‐ and long‐term effects. The present case report describes an accidental exposure of two health‐care workers to ultraviolet radiation produced by a germicidal lamp in a hospital pharmacy. The germicidal lamp presented a spectrum with an intense UV‐C component as well as a modest UV‐B contribution. Overexposure to UV‐C radiation was over 100 times as large as the ICNIRP exposure limits. A few hours after the exposure, the two subjects reported symptoms of acute UV injury and both of them continued having significant clinical signs for over 2 years. In this study, we describe acute and potentially irreversible effects caused by high UV exposure. In addition, we present the results of risk assessment by occupational exposure to germicidal lamps.
Vaccine | 2014
Salvatore Zaffina; Valentina Marcellini; Anna Paola Santoro; Marco Scarsella; Vincenzo Camisa; Maria Vinci; Anna Maria Musolino; Luciana Nicolosi; M. Manuela Rosado; Rita Carsetti
Hepatitis B is a major infectious occupational hazard for health care workers and can be prevented with a safe and effective vaccine. The serum titer of anti-HBsAg antibodies is the most commonly used correlate of protection and post-vaccination anti-HBsAg concentrations of ≥ 10 mIU/ml are considered protective. Subjects with post-vaccination anti-HBsAg titers of <10 mIU/ml 1-6 months post-vaccination, who tested negative for HBsAg and anti-HBc, are defined as non-responders. The question of whether non-responders should be repeatedly vaccinated is still open. The aim of the study was to (i) evaluate the distribution of lymphocyte subpopulations and the percentage of HBsAg-specific memory B cells in responders and non-responders (ii) assess whether non-responders can be induced to produce antibodies after administration of a booster dose of vaccine (iii) determine whether booster vaccination increases the number of specific memory B cells in non-responders. Combining flow-cytometry, ELISPOT and serology we tested the integrity and function of the immune system in 24 health care workers, confirmed to be non-responders after at least three vaccine injections. We compared the results with those obtained in 21 responders working in the same institution. We found that the great majority of the non-responders had a functional immune system and a preserved ability to respond to other conventional antigens. Our most important findings are that the frequency of HBsAg-specific memory B cells is comparable in non-responders and controls and that booster immunization does not lead either to antibody production or memory B cell increase in non-responders.
Bioelectromagnetics | 2016
Maria Grazia Iachininoto; Vincenzo Camisa; Lucia Leone; Rosanna Pinto; Vanni Lopresto; Caterina Merla; Ezio Giorda; Rita Carsetti; Salvatore Zaffina; Maria Vittoria Podda; Luciana Teofili; Claudio Grassi
This study investigates effects of gradient magnetic fields (GMFs) emitted by magnetic resonance imaging (MRI) devices on hematopoietic stem cells. Field measurements were performed to assess exposure to GMFs of staff working at 1.5 T and 3 T MRI units. Then an exposure system reproducing measured signals was realized to expose in vitro CD34+ cells to GMFs (1.5 T-protocol and 3 T-protocol). CD34+ cells were obtained by Fluorescence Activated Cell Sorting from six blood donors and three MRI-exposed workers. Blood donor CD34+ cells were exposed in vitro for 72 h to 1.5 T or 3 T-protocol and to sham procedure. Cells were then cultured and evaluated in colony forming unit (CFU)-assay up to 4 weeks after exposure. Results showed that in vitro GMF exposure did not affect cell proliferation but instead induced expansion of erythroid and monocytes progenitors soon after exposure and for the subsequent 3 weeks. No decrease of other clonogenic cell output (i.e., CFU-granulocyte/erythroid/macrophage/megakaryocyte and CFU-granulocyte/macrophage) was noticed, nor exposed CD34+ cells underwent the premature exhaustion of their clonogenic potential compared to sham-exposed controls. On the other hand, pilot experiments showed that CD34+ cells exposed in vivo to GMFs (i.e., samples from MRI workers) behaved in culture similarly to sham-exposed CD34+ cells, suggesting that other cells and/or microenvironment factors might prevent GMF effects on hematopoietic stem cells in vivo. Accordingly, GMFs did not affect the clonogenic potential of umbilical cord blood CD34+ cells exposed in vitro together with the whole mononuclear cell fraction.
Medicina Del Lavoro | 2014
Salvatore Zaffina; Vincenzo Camisa; Elena Monducci; Maria Vinci; Stefano Vicari; Antonio Bergamaschi
Giornale italiano di medicina del lavoro ed ergonomia | 2012
Salvatore Zaffina; Vincenzo Camisa; Andrea Poscia; Mg Tucci; Montaldi; Cerabona; Malgorzata Wachocka; Umberto Moscato
Medicina Del Lavoro | 2016
Marco Lembo; Alessandro Lunghi; Erica Leo; Matteo Ritrovato; Vittorio Cannatà; Carlo Capussotto; Angelo Tirabasso; Salvatore Zaffina; Vincenzo Camisa; Pietro Derrico; Mauro Martella; Enrico Marchetti
Giornale italiano di medicina del lavoro ed ergonomia | 2016
Maria Vinci; Guendalina Dalmasso; Annapaola Santoro; Rita Brugaletta; Vincenzo Camisa; Natalia Bianchi; Giuseppe Di Pinto; Vincenzo Di Ciommo; Massimiliano Raponi; Salvatore Zaffina
Giornale italiano di medicina del lavoro ed ergonomia | 2016
Vincenzo Camisa; Maria Vinci; Annapaola Santoro; Guendalina Dalmasso; Natalia Bianchi; Massimiliano Raponi; Rita Brugaletta; Pietro Derrico; Salvatore Zaffina
Giornale italiano di medicina del lavoro ed ergonomia | 2016
Vincenzo Camisa; Maria Vinci; Annapaola Santoro; Rita Brugaletta; Salvatore Zaffina; Pietro Apostoli
Giornale italiano di medicina del lavoro ed ergonomia | 2016
Umberto Moscato; Fabio Pattavina; Salvatore Zaffina; Carlo Laurini; Vincenzo Camisa; Nicola Continolo; Marina Sammartino; Andrea Poscia; G Colaiacomo; Malgorzata Wachocka; Daniele Ignazio La Milia