Vsevolod Nikolaevich Rudin

The influence of fullerene additives on the structure of polystyrene films

It was shown by electron microscopy and X-ray diffraction that a polystyrene solid with a three-level hierarchical structure was formed when the solvent was evaporated from a solution of polystyrene in o-xylene (polystyrene molecules stuck together united to form a framework). The kinetics of the transformation of formerly dissolved molecules into aggregates could be described by a Fokker-Planck-type equation. Fullerenes introduced into a solution of polystyrene in amounts less than 0.1 wt % transformed aggregated polystyrene molecules into nanocrystals and accelerated the formation of aggregates. The influence of fullerenes on the kinetics of the processes could be correctly described in the continuum approximation taking into account aggregation rate fluctuations.

Sonodynamic therapy of cancer. A comprehensive experimental study

Sonodynamic therapy in combination with antitumor drugs and sonosensitizers (theraphthal and its derivatives) was studied in preclinical testing against malignant tumors. The use of this therapy scheme enhances the destructive effect of ultrasound on tumors, promotes no metastasis, and make therapeutic drugs more bioavailable. The scheme was recommended for clinical use. A solid-phase sonosensitization mechanism was proposed. A possible system of laboratory and in vitro testing for selection of efficient sonosensitizers was outlined.

The problem of optimal technologies for functional materials

AbstractThe work analyzes the possibility of treating the production of a functional material as the realization of the stage of separation of the substance forming the material from a supersaturated medium and the stages of physical and chemical modification of the separated substance. The key kinetic equation of variation of the distribution function of states of the particles of the substance at each stage is formulated, considering the discrete nature of the nucleation, growth, and aggregation of particles. Solutions to continuous versions of the kinetic equation with regard to each stage are given. The conception of the path

Ultrasonic synthesis of hydroxyapatite in non-cavitation and cavitation modes

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Morphological memory of polymers and their use in developing new materials technology

of obtaining the material is introduced in the form of the coupling function of the target properties

Preparation "ostim apatite" for stimulating growth in bone tissue

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