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Featured researches published by W. C. L. Ford.


Archive | 1983

The Effect of Different Substrate Combinations on the Survival of Ram Cauda Epididymal Spermatozoa exposed to 1 m M - RS α-Chlorohydrin

W. C. L. Ford; Anne Harrison

The motility of ram cauda epididymal spermatozoa exposed to 1 mM- RS α-chlorohydrin and their ATP concentration declined dramatically after 15 min incubation with 5 mM-D glucose or 5 mM-D glucose + 10 mM- L lactate + 1 mM-pyruvate. By contrast the effects of α-chlorohydrin were relatively slight in the absence of glucose. The concerted action of α-chlorohydrin and glucose may dissipate energy in a ‘futile cycling’ reaction and this could explain the effective contraceptive action of the drug.


International Journal of Andrology | 1978

Chlorinated Sugars: A Biochemical Approach to the Control of Male Fertility

W. C. L. Ford; G. M. H. Waites


Reproduction | 1977

Effects of the optical isomers of alpha-chlorohydrin on glycolysis by ram testicular spermatozoa and the fertility of male rats.

W. C. L. Ford; Anne Harrison; G. M. H. Waites


International Journal of Andrology | 1979

Inhibition of Glucose Catabolism in Rat, Hamster, Rhesus Monkey and Human Spermatozoa by α-Chlorohydrin

W. C. L. Ford; Anne Harrison; G. L. Takkar; G. M. H. Waites


Reproduction | 1985

The presence of glucose increases the lethal effect of α-chlorohydrin on ram and boar spermatozoa in vitro

W. C. L. Ford; Anne Harrison


Reproduction | 1983

D-[1-14C]Mannitol and [U-14C]sucrose as extracellular space markers for human spermatozoa and the uptake of 2-deoxyglucose

W. C. L. Ford; Anne Harrison


Reproduction | 1983

The activity of glyceraldehyde 3-phosphate dehydrogenase in spermatozoa from different regions of the epididymis in laboratory rodents treated with α-chlorohydrin or 6-chloro-deoxyglucose

W. C. L. Ford; Anne Harrison


Reproduction | 1981

Effects of 6-chloro-6-deoxysugars on glucose oxidation in rat spermatozoa

W. C. L. Ford; Anne Harrison; G. M. H. Waites


Reproduction | 1981

The effect of 6-chloro-6-deoxysugars on adenine nucleotide concentrations in and motility of rat spermatozoa

W. C. L. Ford; Anne Harrison


International Journal of Andrology | 1984

The role of citrate in determining the activity of calcium ions in human semen

W. C. L. Ford; Anne Harrison

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