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Dive into the research topics where W.D. Schultze is active.

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Featured researches published by W.D. Schultze.


Experimental Biology and Medicine | 1974

Plasma Corticosteroid, Circulating Leukocyte and Milk Somatic Cell Responses to Escherichia coli Endotoxin-Induced Mastitis

Max Paape; W.D. Schultze; Claude Desjardins; R.H. Miller

Summary A mammary quarter in each of 4 cows was infused with 0.5 mg E. coli endotoxin to determine its effect on plasma corticosteroids, circulating leukocytes and milk somatic cells. At 1.5 hr following endotoxin infusion, segmented neutrophils decreased 23%, and by 5 hr dropped 93%. A shift left in the differential circulating leukocyte count began at 2.5 hr and reached maximum proportions between 18-24 hr postendotoxin infusion. Circulating lymphocytes, monocytes and eosinophils were all depressed in response to endotoxin. Plasma corticosteroid concentrations increased (P < 0.01) 2 hr following endotoxin infusion, reached maximum concentrations at 4 hr, then returned to prein-fusion concentrations by 12 hr. The initial decrease in circulating lymphocytes at 2.5 hr was not attributed to the lytic effect of the plasma corticosteroids, since depressions in circulating lymphocytes occurred too soon (0.5 hr) after the increase in plasma corticosteroids. The high plasma corticosteroid concentration appeared to have little effect at restoring leukocyte equilibrium, since the concentration of neutrophils and total leukocytes continued to decline up to 4 hr past the initiation of the plasma corticosteroid response. Serum glucose concentrations coincided with peak plasma corticosteroid concentration and appeared to be one of the primary physiological effects mediated by elevated plasma corticosteroid concentrations. Three hours following endotoxin infusion or 1.5 hr after the noted depression in segmented neutrophils, the concentration of milk somatic cells increased from 5.7 × 104 cells/ml milk at 0 hr to 37.5 × 104 cells/ml. However swelling of infused quarters was detected as early as 2 hr postinfusion and was attributed to diapedesis and lysis of neutrophils. Total milk somatic cell concentrations reached maximum proportions at 18 hr, averaging 54 × 106 cells/ml milk. The authors thank Miss Barbara A. Becker, Mr. D. Carroll, Mr. S. T. Kirk, and Mr. A. J. Kral for their excellent technical assistance.


American Journal of Veterinary Research | 1978

Variation among cows in the ability of milk to support phagocytosis and in the ability of polymorphonuclear leukocytes to phagocytose Staphylococcus aureus.

Max Paape; Pearson Re; W.D. Schultze


American Journal of Veterinary Research | 1981

Effect of an intramammary polyethylene device on the concentration of leukocytes and immunoglobulins in milk and on the leukocyte response to Escherichia coli endotoxin and challenge exposure with Staphylococcus aureus.

Max Paape; W.D. Schultze; Aj Guidry; Kortum Wm; B.T. Weinland


Journal of Dairy Science | 1973

Thermal stress and circulating erythrocytes, leucocytes, and milk somatic cells.

Max Paape; W.D. Schultze; R.H. Miller; J.W. Smith


Journal of Dairy Science | 1972

Effectiveness of Postmilking Teat Dips

W.D. Schultze; J.W. Smith


American Journal of Veterinary Research | 1984

Effect on outcome of intramammary challenge exposure with Staphylococcus aureus of somatic cell concentration and presence of an intramammary device

W.D. Schultze; Max Paape


Journal of Dairy Science | 1985

Control of New Intramammary Infection at Calving by Prepartum Teat Dipping

W.D. Schultze


Journal of Dairy Science | 1983

Effects of a Selective Regimen of Dry Cow Therapy on Intramammary Infection and on Antibiotic Sensitivity of Surviving Pathogens

W.D. Schultze


Journal of Dairy Science | 1967

Variation in Cell Content of Milk Associated with Time of Sample Collection. I. Diurnal Variation

J.W. Smith; W.D. Schultze


American Journal of Veterinary Research | 1988

Effect of abraded intramammary device on outcome in lactating cows after challenge exposure with Streptococcus uberis

Max Paape; W.D. Schultze; Corlett Nj; B.T. Weinland

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Max Paape

Agricultural Research Service

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R.H. Miller

United States Department of Agriculture

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J.W. Smith

United States Department of Agriculture

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B.T. Weinland

United States Department of Agriculture

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Aj Guidry

United States Department of Agriculture

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Dulin Am

United States Department of Agriculture

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Joel Bitman

Agricultural Research Service

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D.R. Gilliam

United States Department of Agriculture

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Helene C. Cecil

United States Department of Agriculture

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Kral Aj

United States Department of Agriculture

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