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Featured researches published by W. van Mechelen.


Obesity Reviews | 2008

Tracking of childhood overweight into adulthood: a systematic review of the literature.

Amika S. Singh; C. Mulder; J.W.R. Twisk; W. van Mechelen; M. J. M. Chinapaw

Overweight and obesity in youth are important public health concerns and are of particular interest because of possible long‐term associations with adult weight status and morbidity. The aim of this study was to systematically review the literature and update evidence concerning persistence of childhood overweight. A computerized bibliographical search – restricted to studies with a prospective or retrospective longitudinal design – was conducted. Two authors independently extracted data and assessed the methodological quality of the included studies in four dimensions (i) study population and participation rate; (ii) study attrition; (iii) data collection and (iv) data analysis. Conclusions were based on a rating system of three levels of evidence. A total of 25 publications were selected for inclusion in this review. According to a methodological quality assessment, 13 studies were considered to be of high quality. The majority of these high‐quality studies were published after 2001, indicating that recently published data, in particular, provide us with reliable information. All included studies consistently report an increased risk of overweight and obese youth becoming overweight adults, suggesting that the likelihood of persistence of overweight into adulthood is moderate for overweight and obese youth. However, predictive values varied considerably. Limiting aspects with respect to generalizability and methodological issues are discussed.


Sports Medicine | 1992

Running injuries. A review of the epidemiological literature.

W. van Mechelen

SummaryRunning is one of the most popular leisure sports activities. Next to its beneficial health effects, negative side effects in terms of sports injuries should also be recognised.Given the limitations of the studies it appears that for the average recreational runner, who is steadily training and who participates in a long distance run every now and then, the overall yearly incidence rate for running injuries varies between 37 and 56%. Depending on the specificity of the group of runners concerned (competitive athletes; average recreational joggers; boys and girls) and on different circumstances these rates vary. If incidence is calculated according to exposure of running time the incidence reported in the literature varies from 2.5 to 12.1 injuries per 1000 hours of running.Most running injuries are lower extremity injuries, with a predominance for the knee. About 50 to 75% of all running injuries appear to be overuse injuries due to the constant repetition of the same movement. Recurrence of running injuries is reported in 20 to 70% of the cases. From the epidemiological studies it can be concluded that running injuries lead to a reduction of training or training cessation in about 30 to 90% of all injuries, about 20 to 70% of all injuries lead to medical consultation or medical treatment and 0 to 5% result in absence from work.Aetiological factors associated with running injuries include previous injury, lack of running experience, running to compete and excessive weekly running distance. The association between running injuries and factors such as warm-up and stretching exercises, body height, malalignment, muscular imbalance, restricted range of motion, running frequency, level of performance, stability of running pattern, shoes and inshoe orthoses and running on 1 side of the road remains unclear or is backed by contradicting or scarce research findings. Significantly not associated with running injuries seem age, gender, body mass index, running hills, running on hard surfaces, participation in other sports, time of the year and time of the day.The prevention of sports injuries should focus on changes of behaviour by health education. Health education on running injuries should primarily focus on the importance of complete rehabilitation and the early recognition of symptoms of overuse, and on the provision of training guidelines.


Occupational and Environmental Medicine | 2002

High physical work load and low job satisfaction increase the risk of sickness absence due to low back pain: Results of a prospective cohort study

Wilhelmina E. Hoogendoorn; P.M. Bongers; H.C.W. de Vet; Geertje A. M. Ariëns; W. van Mechelen; L.M. Bouter

Objective: To determine whether physical and psychosocial load at work influence sickness absence due to low back pain. Methods: The research was a part of the study on musculoskeletal disorders, absenteeism, stress, and health (SMASH), a 3 year prospective cohort study on risk factors for musculoskeletal disorders. Workers from 21 companies located throughout The Netherlands participated in the part of this study on sickness absence due to low back pain. The study population consisted of 732 workers with no sickness absences of 3 days or longer due to low back pain in the 3 months before the baseline survey and complete data on the reasons for absences during the follow up period. The mean (range) period of follow up in this group was 37 (7–44) months. Physical load at work was assessed by analyses of video recordings. Baseline information on psychosocial work characteristics was obtained by a questionnaire. Data on sickness absence were collected from company records. The main outcome measure was the rate of sickness absences of 3 days or longer due to low back pain during the follow up period. Results: After adjustment of the work related physical and psychosocial factors for each other and for other potential determinants, significant rate ratios ranging from 2.0 to 3.2 were found for trunk flexion, trunk rotation, lifting, and low job satisfaction. A dose-response relation was found for trunk flexion, but not for trunk rotation or lifting. Non-significant rate ratios of about 1.4 were found for low supervisor support and low coworker support. Quantitative job demands, conflicting demands, decision authority, and skill discretion showed no relation with sickness absence due to low back pain. Conclusions: Flexion and rotation of the trunk, lifting, and low job satisfaction are risk factors for sickness absence due to low back pain. Some indications of a relation between low social support, either from supervisors or coworkers, and sickness absence due to low back pain are also present.


Occupational and Environmental Medicine | 2001

Are neck flexion, neck rotation, and sitting at work risk factors for neck pain? Results of a prospective cohort study

Geertje A. M. Ariëns; Paulien M. Bongers; M. Douwes; Mathilde C. Miedema; Wilhelmina E. Hoogendoorn; G. van der Wal; L.M. Bouter; W. van Mechelen

OBJECTIVE To study the relation between neck pain and work related neck flexion, neck rotation, and sitting. METHODS A prospective cohort study was performed with a follow up of 3 years among 1334 workers from 34 companies. Work related physical load was assessed by analysing objectively measured exposure data (video recordings) of neck flexion, neck rotation, and sitting posture. Neck pain was assessed by a questionnaire. Adjustments were made for various physical factors that were related or not related to work, psychosocial factors, and individual characteristics. RESULTS A significant positive relation was found between the percentage of the working time in a sitting position and neck pain, implying an increased risk of neck pain for workers who were sitting for more than 95% of the working time (crude relative risk (RR) 2.01, 95% confidence interval (95% CI) 1.04 to 3.88; adjusted RR 2.34, 95% CI 1.05 to 5.21). A trend for a positive relation between neck flexion and neck pain was found, suggesting an increased risk of neck pain for people working with the neck at a minimum of 20° of flexion for more than 70% of the working time (crude RR 2.01, 95% CI 0.98 to 4.11; adjusted RR 1.63, 95% CI 0.70 to 3.82). No clear relation was found between neck rotation and neck pain. CONCLUSION Sitting at work for more than 95% of the working time seems to be a risk factor for neck pain and there is a trend for a positive relation between neck flexion and neck pain. No clear relation was found between neck rotation and neck pain.


British Journal of Sports Medicine | 2004

A one season prospective cohort study of volleyball injuries

Evert Verhagen; A.J. van der Beek; L.M. Bouter; Roald Bahr; W. van Mechelen

Objective: To estimate the overall incidence of acute and overuse volleyball injuries, and to describe factors associated with ankle sprains. Methods: 486 players from the second and third Dutch national volleyball divisions participated in the study and were followed prospectively during a whole season. Three measurements were made during the season (baseline, follow up 1, and follow up 2), where all players completed a questionnaire on demographic variables (only at baseline), sports participation, use of preventive measures, and previous injuries. Volleyball exposure during training and matches was recorded for each individual player by the coach on a weekly exposure form. In case of injury the coach provided the injured player with an injury registration form, which had to be completed within one week after the onset of injury. Results: 100 injuries were reported, resulting in an overall injury incidence of 2.6 injuries/1000 hours. The incidence of acute injuries was 2.0/1000 hours. Ankle sprains (n = 41) accounted for most of the acute injuries, and 31 (75%) of all players with an ankle sprain reported a previous ankle sprain. Twenty five overuse injuries were reported. The overall incidence of overuse injuries was 0.6/1000 hours; the back and the shoulder were the most common sites. Conclusions: Ankle sprain is the most common injury in volleyball, accounting for 41% of all volleyball related injuries. Previous injury seems to be an important risk factor for an ankle sprain. Injury prevention programmes should focus on ankle sprains and concentrate on players with previous ankle sprains.


Occupational and Environmental Medicine | 2006

Should office workers spend fewer hours at their computer? A systematic review of the literature

S. IJmker; Maaike A. Huysmans; B.M. Blatter; A.J. van der Beek; W. van Mechelen; P.M. Bongers

Worldwide, millions of office workers use a computer. Reports of adverse health effects due to computer use have received considerable media attention. This systematic review summarises the evidence for a relationship between the duration of work time spent using the computer and the incidence of hand–arm and neck–shoulder symptoms and disorders. Several databases were systematically searched up to 6 November 2005. Two reviewers independently selected articles that presented a risk estimate for the duration of computer use, included an outcome measure related to hand–arm or neck–shoulder symptoms or disorders, and had a longitudinal study design. The strength of the evidence was based on methodological quality and consistency of the results. Nine relevant articles were identified, of which six were rated as high quality. Moderate evidence was concluded for a positive association between the duration of mouse use and hand–arm symptoms. For this association, indications for a dose–response relationship were found. Risk estimates were in general stronger for the hand–arm region than for the neck–shoulder region, and stronger for mouse use than for total computer use and keyboard use. A pathophysiological model focusing on the overuse of muscles during computer use supports these differences. Future studies are needed to improve our understanding of safe levels of computer use by measuring the duration of computer use in a more objective way, differentiating between total computer use, mouse use and keyboard use, attaining sufficient exposure contrast, and collecting data on disability caused by symptoms.


European Journal of Applied Physiology | 1986

Validation of two running tests as estimates of maximal aerobic power in children

W. van Mechelen; H. Hlobil; Han C. G. Kemper

SummaryIn order to validate the “Maximal Multistage 20 Meter Shuttle Run Test” by Leger and Lambert (1982) (20-MST) as an estimate of maximal aerobic power (


Obesity Reviews | 2011

Relationship between young peoples' sedentary behaviour and biomedical health indicators: a systematic review of prospective studies

M. J. M. Chinapaw; Karin I. Proper; Johannes Brug; W. van Mechelen; Amika S. Singh


BMJ | 2010

Randomised controlled trial of integrated care to reduce disability from chronic low back pain in working and private life

L.C. Lambeek; W. van Mechelen; Dirk L. Knol; Patrick Loisel; Johannes R. Anema

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British Journal of Sports Medicine | 2008

Walking or vitamin B for cognition in older adults with mild cognitive impairment? A randomised controlled trial

J. van Uffelen; M. J. M. Chinapaw; W. van Mechelen; Marijke Hopman-Rock

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J.W.R. Twisk

VU University Medical Center

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H.C.G. Kemper

VU University Medical Center

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A.J. van der Beek

VU University Medical Center

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Johannes R. Anema

VU University Medical Center

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J. Snel

University of Amsterdam

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K.I. Proper

VU University Amsterdam

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G.B. Post

University of Amsterdam

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H.C.W. de Vet

VU University Medical Center

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M. J. M. Chinapaw

VU University Medical Center

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