Wajahat Ali Khan

An Adaptive Semantic based Mediation System for Data Interoperability among Health Information Systems

Heterogeneity in the management of the complex medical data, obstructs the attainment of data level interoperability among Health Information Systems (HIS). This diversity is dependent on the compliance of HISs with different healthcare standards. Its solution demands a mediation system for the accurate interpretation of data in different heterogeneous formats for achieving data interoperability. We propose an adaptive AdapteRInteroperability ENgine mediation system called ARIEN, that arbitrates between HISs compliant to different healthcare standards for accurate and seamless information exchange to achieve data interoperability. ARIEN stores the semantic mapping information between different standards in the Mediation Bridge Ontology (MBO) using ontology matching techniques. These mappings are provided by our System for Parallel Heterogeneity (SPHeRe) matching system and Personalized-Detailed Clinical Model (P-DCM) approach to guarantee accuracy of mappings. The realization of the effectiveness of the mappings stored in the MBO is evaluation of the accuracy in transformation process among different standard formats. We evaluated our proposed system with the transformation process of medical records between Clinical Document Architecture (CDA) and Virtual Medical Record (vMR) standards. The transformation process achieved over 90 % of accuracy level in conversion process between CDA and vMR standards using pattern oriented approach from the MBO. The proposed mediation system improves the overall communication process between HISs. It provides an accurate and seamless medical information exchange to ensure data interoperability and timely healthcare services to patients.

The Mining Minds digital health and wellness framework

BackgroundThe provision of health and wellness care is undergoing an enormous transformation. A key element of this revolution consists in prioritizing prevention and proactivity based on the analysis of people’s conducts and the empowerment of individuals in their self-management. Digital technologies are unquestionably destined to be the main engine of this change, with an increasing number of domain-specific applications and devices commercialized every year; however, there is an apparent lack of frameworks capable of orchestrating and intelligently leveraging, all the data, information and knowledge generated through these systems.MethodsThis work presents Mining Minds, a novel framework that builds on the core ideas of the digital health and wellness paradigms to enable the provision of personalized support. Mining Minds embraces some of the most prominent digital technologies, ranging from Big Data and Cloud Computing to Wearables and Internet of Things, as well as modern concepts and methods, such as context-awareness, knowledge bases or analytics, to holistically and continuously investigate on people’s lifestyles and provide a variety of smart coaching and support services.ResultsThis paper comprehensively describes the efficient and rational combination and interoperation of these technologies and methods through Mining Minds, while meeting the essential requirements posed by a framework for personalized health and wellness support. Moreover, this work presents a realization of the key architectural components of Mining Minds, as well as various exemplary user applications and expert tools to illustrate some of the potential services supported by the proposed framework.ConclusionsMining Minds constitutes an innovative holistic means to inspect human behavior and provide personalized health and wellness support. The principles behind this framework uncover new research ideas and may serve as a reference for similar initiatives.

On curating multimodal sensory data for personalized health and wellness services

In recent years, the focus of healthcare and wellness technologies has shown a significant shift towards personal vital signs devices. The technology has evolved from smartphone-based wellness applications to fitness bands and smartwatches. The novelty of these devices is the accumulation of activity data as their users go about their daily life routine. However, these implementations are device specific and lack the ability to incorporate multimodal data sources. Data accumulated in their usage does not offer rich contextual information that is adequate for providing a holistic view of a user’s lifelog. As a result, making decisions and generating recommendations based on this data are single dimensional. In this paper, we present our Data Curation Framework (DCF) which is device independent and accumulates a user’s sensory data from multimodal data sources in real time. DCF curates the context of this accumulated data over the user’s lifelog. DCF provides rule-based anomaly detection over this context-rich lifelog in real time. To provide computation and persistence over the large volume of sensory data, DCF utilizes the distributed and ubiquitous environment of the cloud platform. DCF has been evaluated for its performance, correctness, ability to detect complex anomalies, and management support for a large volume of sensory data.

Mapping evolution of dynamic web ontologies

Information on the web and web services that are revised by stakeholders is growing incredibly. The presentation of this information has shifted from a representational model of web information with loosely clustered terminology to semi-formal terminology and even to formal ontology. Mediation (i.e., mapping) is required for systems and services to share information. Mappings are established between ontologies in order to resolve terminological and conceptual incompatibilities. Due to new discoveries in the field of information sharing, the body of knowledge has become more structured and refined. The domain ontologies that represent bodies of knowledge need to be able to accommodate new information. This allows for the ontology to evolve from one consistent state to another. Changes in resources cause existing mappings between ontologies to be unreliable and stale. This highlights the need for mapping evolution (regeneration) as it would eliminate the discrepancies from the existing mappings. In order to re-establish the mappings between dynamic ontologies, the existing systems require a complete mapping process to be restructured, and this process is time consuming. This paper proposes a mapping reconciliation approach between the updated ontologies that has been found to take less time to process compared to the time of existing systems when only the changed resources are considered and also eliminates the staleness of the existing mappings. The proposed approach employs the change history of ontology in order to store the ontology change information, which helps to drastically reduce the reconciliation time of the mappings between dynamic ontologies. A comprehensive evaluation of the performance of the proposed system on standard data sets has been conducted. The experimental results of the proposed system in comparison with six existing mapping systems are provided in this paper using 13 different data sets, which support our claims.

Personalized-Detailed Clinical Model for Data Interoperability Among Clinical Standards

OBJECTIVE Data interoperability among health information exchange (HIE) systems is a major concern for healthcare practitioners to enable provisioning of telemedicine-related services. Heterogeneity exists in these systems not only at the data level but also among different heterogeneous healthcare standards with which these are compliant. The relationship between healthcare organization data and different heterogeneous standards is necessary to achieve the goal of data level interoperability. We propose a personalized-detailed clinical model (P-DCM) approach for the generation of customized mappings that creates the necessary linkage between organization-conformed healthcare standards concepts and clinical model concepts to ensure data interoperability among HIE systems. MATERIALS AND METHODS We consider electronic health record (EHR) standards, openEHR, and HL7 CDA instances transformation using P-DCM. P-DCM concepts associated with openEHR and HL7 CDA help in transformation of instances among these standards. We investigated two datasets: (1) data of 100 diabetic patients, including 50 each of type 1 and type 2, from a local hospital in Korea and (2) data of a single Alzheimers disease patient. P-DCMs were created for both scenarios, which provided the basis for deriving instances for HL7 CDA and openEHR standards. RESULTS For proof of concept, we present case studies of encounter information for type 2 diabetes mellitus patients and monitoring of daily routine activities of an Alzheimers disease patient. These reflect P-DCM-based customized mappings generation with openEHR and HL7 CDA standards. Customized mappings are generated based on the relationship of P-DCM concepts with CDA and openEHR concepts. CONCLUSIONS The objective of this work is to achieve semantic data interoperability among heterogeneous standards. This would lead to effective utilization of resources and allow timely information exchange among healthcare systems.

An innovative platform for person-centric health and wellness support

Modern digital technologies are paving the path to a revolutionary new concept of health and wellness care. Nowadays, many new solutions are being released and put at the reach of most consumers for promoting their health and wellness self-management. However, most of these applications are of very limited use, arguable accuracy and scarce interoperability with other similar systems. Accordingly, frameworks that may orchestrate, and intelligently leverage, all the data, information and knowledge generated through these systems are particularly required. This work introduces Mining Minds, an innovative framework that builds on some of the most prominent modern digital technologies, such as Big Data, Cloud Computing, and Internet of Things, to enable the provision of personalized healthcare and wellness support. This paper aims at describing the efficient and rational combination and interoperation of these technologies, as well as their integration with current and future personalized health and wellness services and business.

Process interoperability in healthcare systems with dynamic semantic web services

Healthcare systems are very complex due to extreme heterogeneity in their data and processes. Researchers and practitioner need to make systems interoperable and integrate for the benefit of all the stakeholders including hospitals, clinicians, medical support staff, and patients. The broader goal of interoperability can only be achieved when standards are practiced.Two different healthcare systems can earn HL7 conformance and compliance but at the same time can be incompatible for interoperability because of varying implementation of HL7 interaction model. This is mainly because workflows in healthcare systems are very complex. Interoperability on one hand requires flexible mechanism for the mapping of business processes to a standard, HL7 in our example. On the other hand it requires deeper understanding of the standard interaction model and gaps created by their incompatible implementations. In this paper we propose a novel technique of dynamically creating semantic web services as overlay on top of the existing services. We used Web Service Modeling Framework as an underlying architecture for HL7 process artifacts implementation as semantic web services. These semantic services are mapped to our proposed interaction ontology. Integrated reasoning mechanism provides necessary execution semantics for more effective and seamless end-to-end communication.The prototype we tested on different processes from the laboratory domain at a local diagnostic laboratory with uninterrupted process flow. The scenario of Result Query Placer interaction flow and its associated process artifacts are executed for the proof of concept.The proposed solution complements the existing data interoperability in HL7 and leads to semantic process interoperability. The achievement of semantic interoperability results in timely delivery of healthcare services to patients saving precious lives.

Clinical Decision Support Service for elderly people in smart home environment

With the advent of smart technologies potential ideas have been emerged to facilitate human lives. Based on sensor technologies, smart homes concept is prevailing now a days that intends to bring tremendous changes in human lifestyle. The most prominent application is to equip the smart home with monitoring system that facilitate in managing care for elderly people. Elderly people with chronic disease need continuous care for managing their activities specially medications. The cost is increasing on care of elderly people and often needs sparing of family resource to take care during management of their activities and medications. This paper propose idea of Clinical Decision Support Service (CDSS) that provides guidelines and recommendation based on observed activities of patient. Our proposed CDSS service called Smart CDSS is deployed on platform that support various sensors and emotion recognition applications. The Smart CDSS knowledge base is currently supporting diabetes rules extracted from online resources and validated against recommendation from physician for 100 patients during their visits to local hospital. The Smart CDSS service allow interaction through standard base interfaces following HL7 vMR standard that allow seamless integration to underlying platform. Moreover, HL7 Arden Syntax is incorporated to scale up knowledge base for other diseases and allows sharing of clinician knowledge.

Ontology-Based High-Level Context Inference for Human Behavior Identification

Recent years have witnessed a huge progress in the automatic identification of individual primitives of human behavior, such as activities or locations. However, the complex nature of human behavior demands more abstract contextual information for its analysis. This work presents an ontology-based method that combines low-level primitives of behavior, namely activity, locations and emotions, unprecedented to date, to intelligently derive more meaningful high-level context information. The paper contributes with a new open ontology describing both low-level and high-level context information, as well as their relationships. Furthermore, a framework building on the developed ontology and reasoning models is presented and evaluated. The proposed method proves to be robust while identifying high-level contexts even in the event of erroneously-detected low-level contexts. Despite reasonable inference times being obtained for a relevant set of users and instances, additional work is required to scale to long-term scenarios with a large number of users.

Achieving interoperability among healthcare standards: building semantic mappings at models level

Resolving heterogeneities between data and processes paves the way for interoperability between different heterogeneous systems. Healthcare standards provide the base for interoperability between different Electronic Health Record (EHR) system. The problems related to data interoperability arise when two EHR systems are complaint to heterogeneous healthcare standards and want to communicate with each other. To achieve semantic data interoperability, there is need to resolve data level heterogeneity. In this paper, we propose system that enable high level of accuracy of mapping between heterogeneous healthcare standards model. The broader goal of data interoperability is achieved when these heterogeneities are resolved through ontology matching and generation of accurate mapping file, that helps in clinical message conversion from one standard to another. To justify claim we investigate HL7 and openEHR standards ontological mappings. We will discuss transformation of HL7 and openEHR models at high level and instance transformation at the realization level. The proposed approach provides accurate mappings that enables timely health information sharing among different healthcare systems to provide better healthcare to patients.