Walter Fleischmann

Sexual Infantilism in Females1

IN ANOTHER PAPER we (1) have discussed the failure of normal sexual development resulting from agenesis of the ovary and usually associated with a growth deficiency. There are a number of other conditions which cause failure of sexual maturation in the female. We shall attempt to classify them and shall present a number of cases of different types. CLASSIFICATION As shown in the accompanying table lack of development of the breasts, vagina and uterus and absence of the menarche may result either (a) from primary ovarian deficiency or (b) from a failure of the pituitary to produce the gonadotropic hormones which stimulate the maturation of the ovarian follicles. Primary Ovarian Deficiency. We have reported four cases and have collected eight others from the literature in which there is substantial pathological evidence that the gonads never developed beyond the stage of the genital ridge which is found in the embryo of 5–7 mm.

Sexual Infantilism in Females1: Causes, Diagnosis and Treatment2

IN ANOTHER PAPER we (1) have discussed the failure of normal sexual development resulting from agenesis of the ovary and usually associated with a growth deficiency. There are a number of other conditions which cause failure of sexual maturation in the female. We shall attempt to classify them and shall present a number of cases of different types. CLASSIFICATION As shown in the accompanying table lack of development of the breasts, vagina and uterus and absence of the menarche may result either (a) from primary ovarian deficiency or (b) from a failure of the pituitary to produce the gonadotropic hormones which stimulate the maturation of the ovarian follicles. Primary Ovarian Deficiency. We have reported four cases and have collected eight others from the literature in which there is substantial pathological evidence that the gonads never developed beyond the stage of the genital ridge which is found in the embryo of 5–7 mm.

Sexual Infantilism in FemalesCauses, Diagnosis and Treatment

IN ANOTHER PAPER we (1) have discussed the failure of normal sexual development resulting from agenesis of the ovary and usually associated with a growth deficiency. There are a number of other conditions which cause failure of sexual maturation in the female. We shall attempt to classify them and shall present a number of cases of different types. CLASSIFICATION As shown in the accompanying table lack of development of the breasts, vagina and uterus and absence of the menarche may result either (a) from primary ovarian deficiency or (b) from a failure of the pituitary to produce the gonadotropic hormones which stimulate the maturation of the ovarian follicles. Primary Ovarian Deficiency. We have reported four cases and have collected eight others from the literature in which there is substantial pathological evidence that the gonads never developed beyond the stage of the genital ridge which is found in the embryo of 5–7 mm.

PRIORITY IN THE DISCOVERY OF FEVER THERAPY IN PSYCHOSIS

To the Editor:— I have read with great interest the editorial on Priority in the Discovery of Fever Therapy in Psychosis, April 8. I feel, however, that it contains one statement which should be corrected in the interest of historical accuracy. The editorial closes with the sentence Possibly Wagner-Jauregg was not aware of the work of Dr. Rosenblium because of its publication in an obscure paper in a language little read outside the country of its origin. Wagner-Jauregg in his paper Ueber die Einwirkung fieberhafter Erkrankungen auf Psychosen ( Jahrb. f. Psychiat. 7 :1887) mentions Rosenbliums work: Oks, who reports the experience of Rosenblium, says in a footnote that of the 22 cases or recurrent fever reported by Rosenblium 12 were produced by inoculation.... This may be the first successful trial of artificially induced infectious diseases for therapeutic purposes in psychiatry. In the same paper Wagner-Jauregg mentions the experiments of his