Walter G. Unglaub

Human studies of biologic availability of niacin in coffee.

Summary Coffee contains a significant amount of niacin which is biologically available for man. This beverage can furnish an appreciable share of daily requirement of niacin and should be considered in estimating the niacin content of the human diet.

Vit. B12 levels in serum and urine following parenteral administration of crystalline vit. B12 or liver extract.

Summary Liver extract and crystalline vit. B12 were administered in equivalent amounts to 2 groups of normal subjects, and total serum vit. B12 levels, bound vit. B12 levels, and urinary excretion of vit. B12 compared in the 2 groups. Concentration of free vit. B12 was higher in the group receiving crystalline vitamin. Over the 24-hour period, percentage of bound vitamin serum was greater in the group receiving liver extract. Urinary excretion of vit. B12 was significantly lower in the group receiving liver extract.SummaryLiver extract and crystalline vit. B12 were administered in equivalent amounts to 2 groups of normal subjects, and total serum vit. B12 levels, bound vit. B12 levels, and urinary excretion of vit. B12 compared in the 2 groups. Concentration of free vit. B12 was higher in the group receiving crystalline vitamin. Over the 24-hour period, percentage of bound vitamin serum was greater in the group receiving liver extract. Urinary excretion of vit. B12 was significantly lower in the group receiving liver extract.