Walter S. Burrage

Microscopic observations of the pulmonary arterioles, capillaries, and venules of living mammals before and during anaphylaxis.

Abstract 1.1. The morphology and physiology of the small blood vessels of the lungs of living guinea pigs and rabbits have been discussed. 2.2. Changes in these pulmonary blood vessels during anaphylaxis have been reported.

The effect of ACTH on the immediate skin reaction and passive transfer test in man.

Abstract 1.1. Ten hay fever patients were given 20 mg. of ACTH intramuscularly every 6 hours for 8 doses. 2.2. Discomfort of hay fever in the 4 patients with active symptoms disappeared temporarily. 3.3. ACTH in the dosage and time interval outlined did not significantly alter the positive scratch or passive transfer skin tests. 4.4. Adrenal response to ACTH was demonstrated by a fall in circulating eosinophils in all of the 10 patients and by a rise in urinary 17-ketosteroids in 6 cases.

The role of cortisone in the treatment of severe bronchial asthma.

CORTISONE has become increasingly available for therapy, and many investigators1 2 3 4 5 6 7 8 9 10 have reported its dramatic role in the relief of asthmatic attacks; yet the mechanism by which it...

Maintenance cortisone in severe bronchial asthma

Abstract 1.1. Six patients with severe bronchial asthma have been cleared with cortisone. 2.2. It has been possible to maintain these patients free of asthma for months with suitable daily doses of cortisone. 3.3. No untoward pharmacologic effects of cortisone have been noted to date. 4.4. Cortisone does seem to precipitate clumping of the cellular elements of the blood of the bulbar conjunctiva and to cause edema to appear in these areas.

THE USE OF CORTISONE AND HYDROCORTISONE IN ALLERGY

Excerpt INTRODUCTION During the last few years compound E (cortisone) and compound F (hydrocortisone) have been used with considerable success to suppress the symptoms of allergic and related disor...

Effects of histamine and epinephrine on the small pulmonary blood vessels of living rabbits

Abstract 1.1. The actions of lethal doses of histamine on the small pulmonary blood vessels of living, anesthetized rabbits include dilatation of capillaries, contraction of arterioles and venules, the formation of emboli, and a slowing and finally stagnation of linear blood flow. 2.2. Epinephrine constricts the small arterioles and venules for about one minute. Dilatation follows constriction. During constriction, rate of linear blood flow is slow, but during dilatation the rate is very rapid.

Removal of ragweed pollen from environmental atmosphere of patients; the evaluation of an electrostatic precipitator combined with an air conditioner.

T HE etiology of ragweed pollinosis and ragweed asthma is known. One method of therapy-separation of the patient from the pollen-will result in complete relief of symptoms. At least tens of thousands, however, still suffer when Ambrosia pollinates. Not all these victims can voyage to midocean or escape to other areas free of the offending agent. Another approach has been the development of devices designed to clear pollen from the air of the patient’s room. Beginning with van Leeuwen in 1924,l investigators+lo have described several types of equipment able to perform with varying success. Some of these authors have stressed technical difficulties and have envisioned more satisfactory clinical results when better machines become available. This article considers an electrostatic precipitatort which has been combined with an air conditioner.3 This combination represents a logical answer to complaints that air cleaners without air conditioning are unbearable in hot weather.