Wanderson Silva Batista
Oswaldo Cruz Foundation
Network
Latest external collaboration on country level. Dive into details by clicking on the dots.
Publication
Featured researches published by Wanderson Silva Batista.
Parasitology Research | 2009
Gabriel Melo de Oliveira; Tshaca Mahatma da Silva; Wanderson Silva Batista; Marcello Franco; Nestor Schor
Experimental acute infection with Trypanosoma cruzi in mice promotes an intense myocarditis and other systemic changes. However, the network of pathophysiological disorders and renal injury caused by the infection has not been elucidated. Our previous results with a murine model observed a discrete acute myocarditis and high mortality with significant inflammatory kidney injury with T. cruzi infection. The aim of this study was to investigate the mechanisms of kidney injury caused by the parasite in mice during the experimental acute phase. Results employing BALB/c mice infected with T. cruzi of Y strain showed renal injury on the 6th day postinfection (dpi) caused by a transitory decrease of renal blood flow. Acute kidney injury (AKI) was also observed similar to the model of ischemia/reperfusion lesion in these infected mice. The injury was not related to the presence (or multiplication) of parasites. Only rare nests were microscopically detected, and the presence of scattered parasites in renal parenchyma was seen on the 15th dpi. Thus, it was observed that during the acute phase of the disease, AKI in infected mice is linked to early cardiovascular effects, including heart failure, caused by striking inflammatory lesions in the myocardium, which lead to the high mortality rate of animals.
Memorias Do Instituto Oswaldo Cruz | 2012
Diana Rodrigues da Silva; Solange L. de Castro; Monique Castro da Silva Alves; Wanderson Silva Batista; Gabriel Melo de Oliveira
Trypanosoma cruzi infection has a large public health impact in Latin American countries. Although the transmission rates via blood transfusions and insect vectors have declined sharply in the past 20 years due to policies of the Southern Cone countries, a large number of people are still at risk for infection. Currently, no accepted experimental model or descriptions of the clinical signs that occur during the course of acute murine infection are available. The aim of this work was to use non-invasive methods to evaluate the clinical signs of Balb/c mice infected with the Y strain of T. cruzi. The infected mice displayed evident clinical changes beginning in the third week of infection. The mice were evaluated based on physical characteristics, spontaneous activity, exploratory behaviour and physiological alterations. We hope that the results presented in this report provide parameters that complement the effective monitoring of trypanocidal treatment and other interventions used to treat experimental Chagas disease.
American Journal of Pathology | 2007
Gabriel Melo de Oliveira; Rafaela Lopes Diniz; Wanderson Silva Batista; Marcelo M. Batista; Cristiane Bani Corrêa; Tânia Cremonini de Araújo-Jorge; Andrea Henriques-Pons
Molecular Biology International | 2011
Solange L. de Castro; Denise da Gama Jaen Batista; Marcos Meuser Batista; Wanderson Silva Batista; Anissa Daliry; Elen Mello de Souza; Rubem F. S. Menna-Barreto; Gabriel Melo de Oliveira; Kelly Salomão; Cristiane França da Silva; Patricia Bernardino da Silva; Maria de Nazaré C. Soeiro
Parasitology Research | 2008
Gabriel Melo de Oliveira; Monica de Melo Medeiros; Wanderson Silva Batista; Renata Santana; Tania C. de Araújo-Jorge; Andréa Pereira de Souza
Parasitology Research | 2010
Monica de Melo Medeiros; Tania C. de Araújo-Jorge; Wanderson Silva Batista; Tshaca Mahatma da Silva; Andréa Pereira de Souza
Revista da Sociedade Brasileira de Ciência em Animais de Laboratório | 2013
Maria Alice do Amaral Kuzel; Fernanda da Silva Oliveira; Kelly Cristina Demarque; Janaína Alves Rangel; Frederico Villas Boas Rodrigues; Wanderson Silva Batista; Lucas dos Santos Gameiro; Gabriel Melo de Oliveira
Revista da Sociedade Brasileira de Ciência em Animais de Laboratório | 2014
Fernanda da Silva Oliveira; Janaína Alves Rangel; Wanderson Silva Batista; Lucas dos Santos Gameiro; Gabriel Melo de Oliveira
Revista da Sociedade Brasileira de Ciência em Animais de Laboratório | 2014
Fernanda da Silva Oliveira; Kelly Cristina Demarque; Janaína Alves Rangel; Wanderson Silva Batista; Lucas dos Santos Gameiro; Gabriel Melo de Oliveira
Archive | 2014
Kelly Cristina Demarque; Janaína Alves Rangel; Maria Alice do Amaral Kuzel; Frederico Villas; Boas Rodrigues; Fernanda da Silva Oliveira; Tathiana A. Alvarenga; Monica L. Andersen; Sergio Tufik; Wanderson Silva Batista; Lucas dos Santos Gameiro; Gabriel Melo de Oliveira