Wang Naili

Polyketides from a marine sponge-derived fungus Mycelia sterilia and proton–proton long-range coupling

A series of polyketide‐originated metabolites (1–5) were isolated from a marine sponge‐derived fungus Mycelia sterilia. Of these, 1–3 were new compounds. Their structures were elucidated by spectroscopic methods as (4R*, 5S*, 6S*, 8S*, 13R*)‐1‐(2,8‐dihydroxy‐1,2,6‐trimethyl‐1,2,6,7,8,8a‐hexahydro‐naphthalen‐1‐yl)‐3‐methoxy‐propan‐1‐one (1), 4,8‐dihydroxy‐7‐(2‐hydroxy‐ethyl)‐6‐methoxy‐3,4‐dihydro‐2H‐naphthalen‐1‐one (2) and 1‐methyl‐naphthalene‐2,6‐dicarboxylic acid (3). In 1, the proton–proton long‐range coupling phenomenon claimed attention and was discussed. Copyright