Warren A. Bennett

Platelet thrombosis in leukemia.

Excerpt Capillary thrombosis is observed in a number of conditions. Extensive involvement has been reported in a variety of diseases, such as rickettsial infections,1disseminated lupus erythematosu...

Gonadotropins of the Pituitary Gland and Urine of the Adult Human Male

Summary A method is described whereby the ratio of FSH and LH present in human pituitary tissue can be ascertained in terms of well-known qualitative end points in the gonads of hypophysectomized rats of both sexes. Such end points, representing unit responses of FSH and LH, were chosen because they could be readily determined, and because they occurred at the same dosage of pituitary homogenate. It was thus determined that pooled homogenate of the pituitary glands of 3 adult men contained 100 units of FSH and 100 units of LH per pituitary, a ratio of 1:1. By comparison on an equal weight basis with pituitary tissue, the urine of adult men contained only minute amounts of gonadotropins, but proportionately, there was much more FSH relative to LH, in a ratio of much greater than 2:1.

ANTERIOR PITUITARY INSUFFICIENCY (PANHYPOPITUITARISM—SIMMONDS' DISEASE), PITUITARY MYXEDEMA AND CONGESTIVE HEART FAILURE (MYXEDEMA HEART); REPORT OF CASE AND FINDINGS AT NECROPSY

Excerpt Anterior pituitary insufficiency (panhypopituitarism) may result from any pathologic process that destroys the anterior lobe. The most common lesion is the chromophobe tumor. Less frequentl...