Wendy Yoon Mills | Researchain

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Featured researches published by Wendy Yoon Mills.

Bioorganic & Medicinal Chemistry Letters | 2011

Conformationally constrained farnesoid X receptor (FXR) agonists: Heteroaryl replacements of the naphthalene.

Jonathan Y. Bass; Justin A. Caravella; Lihong Chen; Katrina L. Creech; David N. Deaton; Kevin P. Madauss; Harry B. Marr; Robert B. McFadyen; Aaron B. Miller; Wendy Yoon Mills; Frank Navas; Derek J. Parks; Terrence L. Smalley; Paul K. Spearing; Dan Todd; Shawn P. Williams; G. Bruce Wisely

To improve on the drug properties of GSK8062 1b, a series of heteroaryl bicyclic naphthalene replacements were prepared. The quinoline 1c was an equipotent FXR agonist with improved drug developability parameters relative to 1b. In addition, analog 1c lowered body weight gain and serum glucose in a DIO mouse model of diabetes.

Bioorganic & Medicinal Chemistry Letters | 2006

Synthesis and activity of small molecule GPR40 agonists.

Dulce Maria Garrido; David F. Corbett; Kate A. Dwornik; Aaron S. Goetz; Thomas R. Littleton; Steve C. McKeown; Wendy Yoon Mills; Terrence L. Jr. Smalley; Celia P. Briscoe; Andrew J. Peat

Bioorganic & Medicinal Chemistry Letters | 2004

Novel pyrazolopyrimidine derivatives as GSK-3 inhibitors

Andrew J. Peat; Joyce A. Boucheron; Scott Howard Dickerson; Dulce Maria Garrido; Wendy Yoon Mills; Jennifer Poole Peckham; Frank Preugschat; Terrence L. Jr. Smalley; Stephanie L Schweiker; Jayme Lyn Roark Wilson; Tony Y. Wang; Hui-Qiang Q. Zhou; Stephen A. Thomson

Archive | 2003

Pyrazolopyrimidines as kinase inhibitors

Scott Howard Dickerson; Dulce Maria Garrido; Wendy Yoon Mills; Kazuya Kano; Andrew J. Peat; Stephen A. Thomson; Jayme Lyn Roark Wilson; Hui-quiang Q. Zhou

Archive | 2003

Pyrazolopyrimidines as protein kinase inhibitors

Scott Howard Dickerson; Dulce Maria Garrido; Wendy Yoon Mills; Kazuya Kano; Andrew J. Peat; Stephen A. Thomson; Jayme Lyn Roark Wilson; Huiqiang Zhou

Bioorganic & Medicinal Chemistry Letters | 2007

Synthesis of novel anilinoquinolines as c-fms inhibitors

Terrence L. Jr. Smalley; Stanley D. Chamberlain; Wendy Yoon Mills; David L. Musso; Sab Randhawa; John A. Ray; Vicente Samano; Lloyd Frick

Journal of Heterocyclic Chemistry | 2005

Regioselective synthesis of 3,3-diethyl-4-(methylene)-1-quinol-2-ones by an intramolecular microwave assisted heck reaction

Terrence L. Jr. Smalley; Wendy Yoon Mills

Archive | 2007

Nouveaux composés comme antagonistes ou agonistes inverses pour les récepteurs d'opioïdes

Caroline J. Diaz; Curt Dale Haffner; Jason D. Speake; Cunyu Zhang; Wendy Yoon Mills; Paul Kenneth Spearing; David John Cowan; Gary Martin Green

Archive | 2004

Acides aminophenylcyclopropylcarboxyliques et leurs derives servant d'agonistes de gpr40

David F. Corbett; Kate A. Dwornik; Dulce Maria Garrido; Stephen C. McKeown; Wendy Yoon Mills; Andrew J. Peat; Terrence L. Jr. Smalley

Archive | 2003

Inhibiteurs de kinase sous forme de pyrazolopyrimidines

Matthew Lee Brown; Mui Cheung; Scott Howard Dickerson; Dulce Maria Garrido; Wendy Yoon Mills; Yasushi Miyazaki; Andrew J. Peat; Jennifer Poole Peckham; Terrence L. Jr. Smalley; Stephen A. Thomson; James Marvin Veal; Jayme Lyn Roark Wilson

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