Wenjie Lan
Tsinghua University
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Publication
Featured researches published by Wenjie Lan.
Langmuir | 2008
Jianhong Xu; Sumei Li; Wenjie Lan; Guangsheng Luo
A novel microfluidic approach to measure interfacial tension of immiscible fluids rapidly is reported. This method rests upon quantitative force balance analysis of drop formation dynamics in a coaxial microfluidic device. The values of interfacial tension for several two liquids without/with surfactants are measured. These measurements compare well with those measured by the commercial interfacial tensiometry. The viscosity of water phase fluid can also be accurately measured in the same microfluidic device. Several model systems with interfacial tension from 1.0 to 10.0 mN/m and water phase viscosity from 1.0 to 10.0 mPa.s are tested in this work.
Advanced Healthcare Materials | 2012
Jianhong Xu; Hong Zhao; Wenjie Lan; Guangsheng Luo
A novel and simple approach to prepare monodispersed chitosan microspheres with relative small size and controlled structures was developed by combining the solidification methods of solvent extraction and chemical crosslinking in a capillary-embedded microfluidic decive. The microspheres with different structures are used in the field of protein drug controlled release and immobilization lipases and they show different release profiles and good stability, respectively.
Biomedical Microdevices | 2010
Wenjie Lan; Shaowei Li; Jianhong Xu; Guangsheng Luo
This article describes a simple microfluidic method to fabricate chitosan-silica hybrid microspheres in one step. We dissolved tetraethoxysilane (TEOS) into a chitosan/acetic acid aqueous solution to form a chitosan-silica sol, and then emulsified it in an organic phase mainly containing n-octanol and an organic base triotylamine (TOA) via a co-axial microfluidic device. The formed aqueous droplets were solidified because of the extraction of acetic acid and water to the organic phase. The simple method presented has the advantages of controllable sphere diameter, narrow size distribution and good sphericity. The porous structures of the microspheres were displayed by SEM images. It is found that the inner and surface structures can be controlled by adjusting the solidification reagent component. Furthermore, we chemically grafted bovine serum albumin (BSA) on the microspheres. The existence of silica in the chitosan spheres can enhance both of mechanical intensity and protein loading capacity of the microspheres.
Langmuir | 2011
Wenjie Lan; Shaowei Li; Jianhong Xu; Guangsheng Luo
In this work, we describe a novel, simple microfluidic method for fabricating titania-silica core-shell microspheres. Uniform droplets of silica sol were dispersed into an oil phase containing tetrabutyl titanate via a coaxial microfluidic device. The titanium alkoxide hydrolyzed at the water-oil interface after the formation of the aqueous droplets. A gel shell containing the titanium hydroxide formed around the droplets, and the titania-silica core-shell microspheres were obtained after calcinations. The X-ray diffraction results show that titania coatings crystallized into a pure anatase structure. The scanning electron microscopy and energy-dispersive spectrometry characterization shows that the microspheres are monodispersed with uniform titania coating on the surface. The dispersity and size of the microspheres could easily be controlled by changing the microfluidic flow parameters. The titania content on the surface could be adjusted in the large range of 1.0-98.0 mol % by varying the continuous phase composition and the reaction time, and the structures of the core-shell microshperes could also be controlled.
Biomedical Microdevices | 2009
Jianhong Xu; Sumei Li; Chris P. Tostado; Wenjie Lan; Guangsheng Luo
Chemical Engineering Journal | 2013
Hong Zhao; Jianhong Xu; Wenjie Lan; Tao Wang; Guangsheng Luo
Lab on a Chip | 2009
Wenjie Lan; Shaowei Li; Yangcheng Lu; Jianhong Xu; Guangsheng Luo
Microfluidics and Nanofluidics | 2012
Wenjie Lan; Shaowei Li; Jianhong Xu; Guangsheng Luo
Microfluidics and Nanofluidics | 2010
Wenjie Lan; Shaowei Li; Jianhong Xu; Guangsheng Luo
Industrial & Engineering Chemistry Research | 2014
Wenjie Lan; Shaowei Li; Yujun Wang; Guangsheng Luo