Werner Lierse
University of Hamburg
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Featured researches published by Werner Lierse.
Diseases of The Colon & Rectum | 1994
Volker F. Eckardt; Bernd Jung; Bernd Fischer; Werner Lierse
PURPOSE: This study investigates the normal ultrasono graphic morphology of pelvic floor striated muscle and evaluates whether there are differences between males and females and between healthy subjects and patients with idiopathic fecal incontinence. METHODS: Manometric and ultrasonographic studies of the anal canal were performed in 30 healthy volunteers and in 26 patients with idiopathic fecal incontinence. Verification of ultrasonographic findings was obtained by studying anatomic preparations. RESULTS: Ultrasonography reliably identified the internal and external anal sphincter and frequently visualized neighboring structures. In addition, it detected muscular structures that have not clearly been described previously. However, differences in external sphincter function between males and females and between healthy subjects and incontinent patients were not reflected by alterations in muscle thickness. CONCLUSIONS: Endosonography of the anal canal clearly delineates muscular structures and may even visualize structures that have been previously incompletely defined. However, it remains to be shown that differences in certain muscular functions have a morphologic correlate that can be detected by endosonography.
Cells Tissues Organs | 1980
U. Mangold; Werner Lierse; G. Pfeifer
For the -reconstruction of nasal defects, paramedian forehead flaps with a small pedicel are used. The nutrition of these flaps depends on the presence of an arterial blood vessel in the pedicel. In c
Cell and Tissue Research | 1965
Werner Lierse
Nach 3-Acetylpyridingaben findet sich 20 Tage oder 1 Jahr spater im Rattenhirn ein fleckformiges Oedem, das im Cornu Ammonis starker als in der Gros- und Kleinhirnrinde ist. In den Astrozyten, Oligodendrozyten und Perizyten werden granulare und homogene Einschlusse oder eine Kombination beider gefunden. Wenige Glia- und einige verstreut liegende Ganglienzellen sind zugrunde gegangen. In den Perizyten kernen kommen homogene, in den Ganglienzellkernen granulare Einschlusse vor.SummaryTwenty days or one year after 3-acetyl-pyridine was given to rats, a patchy edema is observed in the brain. It is more extensive in the cornu Ammonis than in the cortices of cerebrum and cerebellum. Granular and homogeneous inclusions, or a combination of both, are found in astrocytes, oligodendrocytes, and pericytes. Only a few glial cells and some diffusely distributed ganglion cells are disintegrated. The nuclei of pericytes show homogeneous those of ganglionc ells granular inclusions.ZusammenfassungNach 3-Acetylpyridingaben findet sich 20 Tage oder 1 Jahr später im Rattenhirn ein fleckförmiges Oedem, das im Cornu Ammonis stärker als in der Groß- und Kleinhirnrinde ist. In den Astrozyten, Oligodendrozyten und Perizyten werden granuläre und homogene Einschlüsse oder eine Kombination beider gefunden. Wenige Glia- und einige verstreut liegende Ganglienzellen sind zugrunde gegangen. In den Perizyten kernen kommen homogene, in den Ganglienzellkernen granuläre Einschlüsse vor.
Cells Tissues Organs | 1988
Wolfgang Friedrich; Claus Herberhold; Werner Lierse
This study reports on investigations of the thoracodorsal artery by injection studies.This artery has a long proximal extramuscular course before it enters the muscle. A consistent neurovascular hilum
Cell and Tissue Research | 1961
Werner Lierse
ZusammenfassungIn vier Katzengehirnen wurde der mittlere Kapillarabstand aus dem prozentualen Volumenanteil der Kapillaren am Hirngewebe bestimmt. Der Kapillarabstand ist im Nucleus N. hypoglossi am größten, in der Area postrema der Medulla oblongata am kleinsten. Zwischen beiden Regionen liegen die Werte der Parietalrinde, des Thalamus, des Nucleus N. vestibularis und des Gyrus hippocampi. Diese anatomischen Daten können in die Formeln zur physiologischen Berechnung des Sauerstoffverbrauchs begrenzter Hirnregionen eingesetzt werden und sind eine Fortführung der quantitativen Untersuchungen über die Angioarchitektonik des Gehirns.
Archive | 1967
Lothar Labedsky; Werner Lierse
SummaryUsing the method of Nachlaset al. (1957) the postnatal development of succinate dehydrogenase activity was investigated in the brain of mice. The age of the animals used in the investigation ranged from newborn to 21 days of age. The strength of the activity was estimated microscopically. The development of the brain stem was observed to be earlier than the development of the telencephalon. The results of the tests done on day 0,10 and 20 are described in the paper and summarized in tables. Three types of nerve cells are described: Cells of the somatic type which show a greater SDH activity in the perikaryon than in the surrounding neuropil. Cells of the dendritic type showing the activity predominantly in the neuropil. Cells of an indifferent type where a differentiation is not possible. In cerebral nuclei containing cells of the indifferent type, the activity is first demonstrable in the neuroglia cells and later on in the neurons. In cerebral nuclei with cells of the somatic type the activity is first developed in the neurons and then in the glia cells. The glia in the white matter shows a low to medium strong activity. The activity of the neurites can be localized in an external layer of the axon.ZusammenfassungMit der Methode von Nachlas et al. (1957) wird die Entwicklung der Succinodehydrogenase-Aktivität im Gehirn der Maus postnatal bis zum 21. Tag untersucht. Die Aktivität wird unter dem Mikroskop mit dem Auge abgeschätzt. Es wird eine frühbetonte Entwicklung des Hirnstammes von einer spätbetonten Entwicklung im Endhirn unterschieden. Die Ergebnisse von 0., 10. und 20. Tag werden im Text beschrieben und in Tabellen zusammengefaßt. Es werden drei Typen von Ganglienzellen unterschieden: Zellen vom somatischen Typ, hier ist die Aktivität der SDH im Perikaryon größer als im umgebenden Neuropil, Zellen vom dendritischen Typ, hier ist die Aktivität vorwiegend im Neuropil lokalisiert, Zellen vom indifferenten Typ, wo eine solche Unterscheidung nicht möglich ist. Die Glia zeigt deutlich in Hirnkernen mit Zellen vom indifferenten Typ starke Aktivität vor den Neuronen, in Hirnkernen mit Zellen vom somatischen Typ entwickeln sich die Neurone vor den Gliazellen. Die Glia in der weißen Substanz besitzt geringe bis mittlere Aktivität. Die Aktivität der Neuriten ist in einer äußeren Schicht der Faser im Axon zu lokalisieren.
Cells Tissues Organs | 1988
Friedrich W; Werner Lierse; Herberhold C
In order to clarify the vascularization of the pectoralis major muscle by the pectoral branch of the thoracoacromial artery, morphometric investigations and selective injection studies of the vessel were performed. A comparison with the anatomical orientation points clinically used for locating the vessel and its course confirms that the origin of the artery is at a constant spot at half the sternoacromial distance; the main vessel axis, however, deviates considerably from the clinically used acromioxiphoid axis in lateral direction. The lumen of the thoracoacromial artery has a range of more than 150% of the smallest vessel. Atherosclerotic alterations are not the reason for this variety but only an additional handicap for the vessel capacity. Two types of muscle-perforating arteries were found, and the cutaneous area of blood supply was defined.
Cells Tissues Organs | 1975
W. Schaarschmidt; Werner Lierse
6-Aminonicotinamide (6-AN), an antimetabolite of nicotinamide, damages the astrocytes and oligodendrocytes through a blockade of the pentose phosphate pathway. Both types of glia cells become hydropic
Proceedings of SPIE | 1993
Renate Jahn; Andreas Bleckmann; Edwin W. Duczynski; Hans-Joachim von der Heide; Guenter Huber; K. H. Jungbluth; Werner Lierse; Walter Neu; Bert Struve
The interaction of various pulsed lasers with meniscus and bone of freshly slaughtered bovines and pigs was examined. Our aim was to find lasers useful for accident surgical operations (e.g. bone or callus dystopy inside joints or nearby important vessels or nerves after fractures). Laser wavelengths of the UV- and infrared spectral range were investigated: XeCl- excimer lasers (wavelength 308 nm, pulse duration 28 ns, 60 ns, 300 ns) Nd:YAG (1.06 micrometers , 400 microsecond(s) ), Tm:YAG (2.01 micrometers , 400 microsecond(s) ), Ho:YAG (2.12 micrometers , 400 microsecond(s) ), CrEr:YSGG (2.79 micrometers , 400 microsecond(s) ), and Er:YAG (2.94 micrometers , 400 microsecond(s) ). The excimer laser radiation was guided by a tapered fused silica fiber, whereas for all other lasers the tissue samples were positioned in the focus of a lens with 100 mm focal length. Ablation rates were determined by perforating samples of defined thickness, and the effects of laser ablation on tissue were controlled macroscopically, by light microscopy and by scanning electron microscopy.
Cell and Tissue Research | 1968
B. Biernat; Werner Lierse; H. D. Franke
SummaryThe effect of 200 kV X-irradiation on the hypothalamus and hypophysis of 35 (both male and female) guinea pigs was examined 24, 72, 120, and 240 hours after irradiation of the head. Doses of 500, 1,000, 2,000 and 3,000 R were used at 100 R per minute. 24 hours following irradiation at all doses, a decrease of neurosecretory material occurred in the nucleus supraopticus, nucleus paraventricularis, and in the neurohypophysis. 72 hours following irradiation with 500 R, the amount of neurosecretory material increased and normal levels are attained at 10 days. Higher dosages (1,000 to 3,000 R) prevented the increase observed with 500 R at 72 hours; rather, the animals died after 1 week.ZusammenfassungDer Kopf von insgesamt 35 männlichen und weiblichen Meerschweinchen wurde mit Röntgenstrahlen (200 kV) homogen einzeitig bestrahlt. Die Dosen betrugen 500, 1000, 2000 und 3000 R bei einer Dosisleistung von 100 R/min. Nach allen Dosen wird in den neurosekretorischen Kernen des Hypothalamus und im Hypophysenhinterlappen der Bestand an Neurosekret vermindert. Drei Tage nach den Bestrahlungen mit 500 R nimmt das Neurosekret wieder zu und die Menge normalisiert sich bis zum 10. Tag p. irrad. Nach 1000 bis 3000 R sterben die Tiere nach 1 Woche, ohne daß es zur Restitution der Neurosekretbildung kommt.