Whc Hu

Prevalence, clinical spectrum and health care utilization of gastro-oesophageal reflux disease in a Chinese population: a population-based study

Background : Population‐based data on gastro‐oesophageal reflux disease in Chinese are lacking. The prevalence, clinical spectrum and health care‐seeking behaviour of subjects with gastro‐oesophageal reflux disease were studied.

Anxiety but not depression determines health care-seeking behaviour in Chinese patients with dyspepsia and irritable bowel syndrome: a population-based study

Aims : To study the prevalence of dyspepsia and irritable bowel syndrome and the effects of co‐existing anxiety and depression on health care utilization by a population survey in Chinese.

Randomized controlled study of rabeprazole, levofloxacin and rifabutin triple therapy vs. quadruple therapy as second‐line treatment for Helicobacter pylori infection

Aim : To test the efficacy of rabeprazole, levofloxacin and rifabutin triple therapy vs. quadruple therapy for the second‐line treatment of Helicobacter pylori infection.

Long-term prospective follow-up of endoscopic oesophagitis in southern Chinese - prevalence and spectrum of the disease

Aims : To study the prevalence, clinical characteristics and long‐term outcome of oesophagitis in Chinese patients.

A sensitive guaiac faecal occult blood test is less useful than an immunochemical test for colorectal cancer screening in a Chinese population

Background : Colorectal cancer screening by guaiac faecal occult blood test has been shown to reduce the incidence and mortality of colorectal cancer in Western populations. The optimal faecal occult blood test, whether guaiac or immunochemical, for colorectal cancer screening in the Chinese population remains to be defined.

Symptomatic response to lansoprazole predicts abnormal acid reflux in endoscopy-negative patients with non-cardiac chest pain.

Aim : To determine whether symptomatic response to lansoprazole predicts abnormal acid reflux in endoscopy‐negative patients with non‐cardiac chest pain.

A validated symptoms questionnaire (Chinese GERDQ) for the diagnosis of gastro-oesophageal reflux disease in the Chinese population

Background and aims: To develop a validated gastro‐oesophageal disease (GERD) symptom questionnaire for the Chinese population.

Upper gastrointestinal evaluation of Chinese patients with non-cardiac chest pain

To test the usefulness of upper gastrointestinal investigations and quality of life assessment in Chinese patients with non‐cardiac chest pain.

An evaluation of invasive and non-invasive tests for the diagnosis of Helicobacter pylori infection in Chinese.

Different tests are available for diagnosing Helicobacter pylori infection.

Effect of treatment of Helicobacter pylori on the prevention of gastroduodenal ulcers in patients receiving long-term NSAIDs: a double-blind, placebo-controlled trial

Background : There is controversy as to whether Helicobacter pylori and non‐steroidal anti‐inflammatory drugs interact to cause peptic ulcers.