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William B. Wright

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Publication

Featured researches published by William B. Wright.

Journal of Medicinal Chemistry | 1980

Derivatives of 11-(1-piperazinyl)-5H-pyrrolo[2,1-c][1,4]benzodiazepine as central nervous system agents.

William B. Wright; Eugene N. Greenblatt; Ivana P. Day; Nicanor Quinones Quinones; Robert A. Hardy

Four 11-(1-piperazinyl)-5H-pyrrolo[2,1-c][1,4]benzodiazepines were prepared and evaluated as central nervous system agents. All were active psychotropic agents as determined by animal screening tests. The most interesting compound, 11-(1-piperazinyl)-5H-pyrrolo[2,1-c][1,4]benzodiazepine, showed dual activity as an antidepressant against tetrabenazine depression and as a neuroleptic as measured by protection vs. amphetamine lethality in grouped mice.

Journal of Medicinal Chemistry | 1978

Derivatives of 1,2,3,11a-tetrahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepine-5,11(10H)-dione as anxiolytic agents

William B. Wright; Herbert J. Brabander; Eugene N. Greenblatt; Ivana P. Day; Robert A. Hardy

Journal of Medicinal Chemistry | 1986

Thromboxane synthetase inhibitors and antihypertensive agents. 1. N-[(1H-imidazol-1-yl)alkyl]aryl amides and N-[(1H-1,2,4-triazol-1-yl)alkyl]aryl amides

William B. Wright; Jeffery B. Press; Peter S. Chan; Joseph W. Marsico; Margie F. Haug; Judy Lucas; Jess Tauber; Andrew S. Tomcufcik

Journal of Medicinal Chemistry | 1966

Central nervous system depressants. I. 1-aminoalkyl-3-aryl derivatives of 2-imidazolidinone, 2-imidazolidinethione, and tetrahydro-2(1H)-pyrimidinone.

William B. Wright; Herbert J. Brabander; Robert A. Hardy; Arnold C. Osterberg

Journal of Medicinal Chemistry | 1968

Central nervous system depressants. IV. 2-aminoalkyl-1,2-dihydro-3H-imidazo(1,5-a)indol-3-ones.

William B. Wright; Herbert J. Brabander

Journal of Organic Chemistry | 1962

Alkylation of Amines by Esters and Lithium Aluminum Hydride. II

William B. Wright

Journal of Organic Chemistry | 1961

Synthetic Analgesics. II. Basic Anilides and Carbanilates1

William B. Wright; Herbert J. Brabander; Robert A. Hardy

Journal of Organic Chemistry | 1961

Synthetic Analgesics. III. Basic Anilides and Carbanilates Containing the Phenalkyl Moiety1

William B. Wright; Herbert J. Brabander; Robert A. Hardy

Journal of Organic Chemistry | 1961

The Rearrangement and Cyclization of Ethyl N-(Methylaminoalkyl)carbanilates and 1,1-Dimethyl-3-methylaminoalkyl-3-phenylureas1

William B. Wright; Herbert J. Brabander

Journal of the American Chemical Society | 1959

The Preparation and Identification of the Isomeric 1-Aryl-3(and 5)-methyl-5(and 3)-(4-pyridyl)-pyrazoles

William B. Wright; Herbert J. Brabander; Robert A. Hardy; W. Fulmor

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Herbert J. Brabander

American Cyanamid

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Andrew S. Tomcufcik

American Cyanamid

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Arnold C. Osterberg

American Cyanamid

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Jeffery B. Press

Ohio State University

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John S. Webb

American Cyanamid

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Joseph W. Marsico

American Cyanamid

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Judy Lucas

American Cyanamid

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Nicanor Quinones Quinones

American Cyanamid

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Peter S. Chan

American Cyanamid

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W. Fulmor

American Cyanamid

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