William C. Shoemaker

Effect of Insulin on Rate of Hepatic Uptake of NEFA.

Summary Concentrations of NEFA in plasma of blood obtained from splenic artery, portal and hepatic veins were measured in un-anesthetized dogs together with hepatic plasma flow. Rates of hepatic and non-hepatic splanchnic uptake or output of NEFA were calculated before and after insulin administration. A marked increase in rate of hepatic uptake of NEFA was observed after insulin administration. No significant change in rate of NEFA output from non-hepatic splanchnie area was found.