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Featured researches published by William D. Lopez.


Social Science & Medicine | 2012

Marginalized identities, discrimination burden, and mental health: empirical exploration of an interpersonal-level approach to modeling intersectionality.

Julia S. Seng; William D. Lopez; Mickey Sperlich; Lydia Hamama; Caroline D. Reed Meldrum

Intersectionality is a term used to describe the intersecting effects of race, class, gender, and other marginalizing characteristics that contribute to social identity and affect health. Adverse health effects are thought to occur via social processes including discrimination and structural inequalities (i.e., reduced opportunities for education and income). Although intersectionality has been well-described conceptually, approaches to modeling it in quantitative studies of health outcomes are still emerging. Strategies to date have focused on modeling demographic characteristics as proxies for structural inequality. Our objective was to extend these methodological efforts by modeling intersectionality across three levels: structural, contextual, and interpersonal, consistent with a social-ecological framework. We conducted a secondary analysis of a database that included two components of a widely used survey instrument, the Everyday Discrimination Scale. We operationalized a meso- or interpersonal-level of intersectionality using two variables, the frequency score of discrimination experiences and the sum of characteristics listed as reasons for these (i.e., the persons race, ethnicity, gender, sexual orientation, nationality, religion, disability or pregnancy status, or physical appearance). We controlled for two structural inequality factors (low education, poverty) and three contextual factors (high crime neighborhood, racial minority status, and trauma exposures). The outcome variables we modeled were posttraumatic stress disorder symptoms and a quality of life index score. We used data from 619 women who completed the Everyday Discrimination Scale for a perinatal study in the U.S. state of Michigan. Statistical results indicated that the two interpersonal-level variables (i.e., number of marginalized identities, frequency of discrimination) explained 15% of variance in posttraumatic stress symptoms and 13% of variance in quality of life scores, improving the predictive value of the models over those using structural inequality and contextual factors alone. This studys results point to instrument development ideas to improve the statistical modeling of intersectionality in health and social science research.


PLOS ONE | 2012

Expensive Egos: Narcissistic Males Have Higher Cortisol

David A. Reinhard; Sara H. Konrath; William D. Lopez; Heather Cameron

Background Narcissism is characterized by grandiosity, low empathy, and entitlement. There has been limited research regarding the hormonal correlates of narcissism, despite the potential health implications. This study examined the role of participant narcissism and sex on basal cortisol concentrations in an undergraduate population. Methods and Findings Participants were 106 undergraduate students (79 females, 27 males, mean age 20.1 years) from one Midwestern and one Southwestern American university. Narcissism was assessed using the Narcissistic Personality Inventory, and basal cortisol concentrations were collected from saliva samples in a laboratory setting. Regression analyses examined the effect of narcissism and sex on cortisol (log). There were no sex differences in basal cortisol, F(1,97) = .20, p = .65, and narcissism scores, F(1,97) = .00, p = .99. Stepwise linear regression models of sex and narcissism and their interaction predicting cortisol concentrations showed no main effects when including covariates, but a significant interaction, β = .27, p = .04. Narcissism was not related to cortisol in females, but significantly predicted cortisol in males. Examining the effect of unhealthy versus healthy narcissism on cortisol found that unhealthy narcissism was marginally related to cortisol in females, β = .27, p = .06, but significantly predicted higher basal cortisol in males, β = .72, p = .01, even when controlling for potential confounds. No relationship was found between sex, narcissism, or their interaction on self-reported stress. Conclusions Our findings suggest that the HPA axis is chronically activated in males with unhealthy narcissism. This constant activation of the HPA axis may have important health implications.


Journal of Immigrant and Minority Health | 2017

Health Implications of an Immigration Raid: Findings from a Latino Community in the Midwestern United States.

William D. Lopez; Daniel J. Kruger; Jorge Delva; Mikel Llanes; Charo Ledón; Adreanne Waller; Melanie Harner; Ramiro Martinez; Laura Sanders; Margaret Harner; Barbara A. Israel

Immigration raids exemplify the reach of immigration law enforcement into the lives of Latino community members, yet little research characterizes the health effects of these raids. We examined the health implications of an immigration raid that resulted in multiple arrests and deportations and occurred midway through a community survey of a Latino population. We used linear regression following principal axis factoring to examine the influence of raid timing on immigration enforcement stress and self-rated health. We controlled for age, sex, relationship status, years in the county in which the raid occurred, children in the home, and nativity. 325 participants completed the survey before the raid and 151 after. Completing the survey after the raid was associated with higher levels of immigration enforcement stress and lower self-rated health scores. Findings indicate the negative impact of immigration raids on Latino communities. Immigration discussions should include holistic assessments of health.


Addictive Behaviors | 2010

High-risk drug use and sexual behaviors among out-of-treatment drug users: an aging and life course perspective.

William D. Lopez; Patrick M. Krueger; Scott T. Walters

High-risk injection drug use and its accompanying sexual behaviors have large social and financial costs. However, little is known about how age and age at first drug use are related to high-risk injection or sex behaviors. The current study draws on life course perspectives and data from the NIDA Cooperative Agreement to examine the relationship between eight high-risk behavior variables and age and age at first drug use. Random effects negative binomial regression models reveal that the frequency of high-risk sexual behaviors in the past month decreases up to 28% with each decade of age, although the frequency of high-risk injection behaviors in the past month increases by up to 62% with each decade of age. Both high-risk injection and high-risk sex behaviors are lower among those who initiated first drug use at later ages. Previous research has indicated the importance of interventions to reduce the high-risk sexual behaviors of older drug users. The current study suggests a refocusing of public health efforts on their high-risk injection habits.


Journal of the American Psychiatric Nurses Association | 2013

In search of an adult attachment stress provocation to measure effect on the oxytocin system: a pilot validation study.

Michelle L. Munro; Stephanie L. Brown; Hossein Pournajafi-Nazarloo; C. Sue Carter; William D. Lopez; Julia S. Seng

BACKGROUND: Oxytocin is a promising biomarker for psychiatric conditions arising from early relational trauma, childhood maltreatment, and attachment dysregulation, including posttraumatic stress and dissociative disorders. OBJECTIVE: This exploratory pilot study examined plasma oxytocin as a biomarker for alterations in the attachment system. DESIGN: We used a single group, repeated-measures design with 15 women. The protocol used a film clip previously validated as a provocation to the hypothalamic–pituitary–adrenal axis. RESULTS: The repeated-measures ANOVA showed differences in oxytocin across the three time points. Correlations with oxytocin indicated that measures of dissociation and somatization correlated most strongly with higher levels of oxytocin measured during exposure to the film’s bonding scene and posttraumatic stress disorder correlated most strongly with lower levels at the film’s abandonment scene. Post hoc analyses revealed differences in oxytocin response related to psychopathology. CONCLUSION: Replication studies should characterize participants on a range of psychiatric conditions associated with attachment dysregulation.


The International Quarterly of Community Health Education | 2016

Spatial Stigma and Health in Postindustrial Detroit.

Louis F. Graham; Mark B. Padilla; William D. Lopez; Alexandra Minna Stern; Jerry Peterson; Danya E. Keene

An emerging body of research suggests that those who reside in socially and economically marginalized places may be marked by a stigma of place, referred to as spatial stigma, which influences their sense of self, their daily experiences, and their relations with outsiders. Researchers conducted 60 semistructured interviews at partnering community-based organizations during summer 2011 with African American and Latina/o, structurally disadvantaged youth of diverse gender and sexual identities who were between 18 and 26 years of age residing in Detroit, Michigan. The disadvantaged structural conditions and dilapidated built environment were common themes in participants’ narratives. Beyond these descriptions, participants’ framings and expressions of their experiences in and perceptions of these spaces alluded to reputational qualities of their city and particular areas of their city that appear related to spatial stigma. Young Detroit residents articulated the ways that they experience and navigate the symbolic degradation of their city.


Addictive Behaviors | 2014

Posttraumatic stress disorder, smoking, and cortisol in a community sample of pregnant women

William D. Lopez; Julia S. Seng

BACKGROUND The prevalence of posttraumatic stress disorder (PTSD) in the United States is higher among pregnant women than women generally. PTSD is related to adverse birth outcomes via physiological and behavioral alterations, such as smoking. METHODS We utilize salivary cortisol measures to examine how traumatic stress, smoking and the hypothalamic-pituitary-adrenal axis interact. Pregnant women (n=395) gave cortisol specimens as part of a cohort study of PTSD and pregnancy at three health systems in the Midwestern United States. Women were divided into three groups: nonsmokers, quitters (who stopped smoking during pregnancy), and pregnancy smokers. Mean cortisol values at three points, sociodemographics, trauma history, and PTSD were compared across groups. We assessed the association of smoking group and PTSD with late afternoon cortisol levels. RESULTS Smokers, quitters, and nonsmokers differed on demographic risk factors and PTSD symptom load. Late afternoon and bedtime cortisol measures were significantly positively correlated with smoking in pregnancy, with smokers with PTSD presenting the highest cortisol levels. Regression analysis showed that smoking in pregnancy was associated with higher late afternoon cortisol in an additive manner with PTSD symptoms. CONCLUSIONS Smoking appears to have a different relationship with cortisol level for those with and without PTSD. This is the first study to show additive effects of smoking and PTSD on cortisol levels in pregnant women. Since high cortisol, smoking, and PTSD have been shown to adversely affect perinatal outcomes, and since those continuing to smoke in pregnancy had the highest PTSD symptom load, PTSD-specific smoking cessation programs in maternity settings are warranted.


The International Quarterly of Community Health Education | 2016

Discrimination and Depressive Symptoms Among Latina/o Adolescents of Immigrant Parents.

William D. Lopez; Alana M. W. LeBrón; Louis F. Graham; Andrew Grogan-Kaylor

Discrimination is associated with negative mental health outcomes for Latina/o adolescents. While Latino/a adolescents experience discrimination from a number of sources and across contexts, little research considers how the source of discrimination and the context in which it occurs affect mental health outcomes among Latina/o children of immigrants. We examined the association between source-specific discrimination, racial or ethnic background of the source, and school ethnic context with depressive symptoms for Latina/o adolescents of immigrant parents. Using multilevel linear regression with time-varying covariates, we regressed depressive symptoms on source-specific discrimination, racial or ethnic background of the source of discrimination, and school percent Latina/o. Discrimination from teachers (β = 0.06, p < .05), students (β = 0.05, p < .05), Cubans (β = 0.19, p < .001), and Latinas/os (β = 0.19, p < .001) were positively associated with depressive symptoms. These associations were not moderated by school percent Latina/o. The findings indicate a need to reduce discrimination to improve Latina/o adolescents’ mental health.


Journal of Hispanic Higher Education | 2017

Mentors, Resiliency, and Ganas: Factors Influencing the Success of DACAmented, Undocumented, and Immigrant Students in Higher Education.

Raúl Gámez; William D. Lopez; Betty Overton

Emerging research has explored the psychological and emotional challenges undocumented students encounter while accessing higher education, yet few studies have specifically investigated the factors that facilitate success once admitted. Semistructured interviews with former or current undocumented students suggest that factors such as mentors, individual resiliency, and the ganas to succeed affect students’ navigation strategies in higher education. Interviewees suggest solutions to institutional barriers that mitigate the negative effects of immigration status.


Traumatology | 2018

The traumatogenic potential of law enforcement home raids: An exploratory report.

William D. Lopez; Nicole L. Novak; Melanie Harner; Ramiro Martinez; Julia S. Seng

Reports suggest that tens of thousands of law enforcement home raids are conducted annually, disproportionally occurring in minority communities. Whether conducted by local police or immigration enforcement agents, raids generally involve numerous agents with military weapons entering homes. Because the targets of raids rarely live alone, there are often witnesses, including children. Emerging research shows that law enforcement presence and enforcement methods may contribute to the development of traumatic stress in these communities. Yet despite the frequency and the known paramilitary tactics used, no research of which we are aware has considered the psychological impact of home raids. We conducted a secondary analysis of narrative interviews of 4 individuals in an apartment that was raided by a Special Weapons and Tactics unit and Immigration and Customs Enforcement agents. We used content analysis to extract participant statements that aligned with posttraumatic stress disorder (PTSD) diagnostic criteria. Results suggest that the raid was highly traumatic for those in the residence, who wondered if they or their family members would be shot or killed. Interviewees described many symptoms that would likely fit within PTSD diagnostic criteria, including nightmares, suicidality, avoidance of triggering stimuli (e.g., government officials), and the inability to care for their children. A time frame for presentations of symptoms could not be assessed. This study suggests that individuals exposed to law enforcement home raids would likely meet diagnostic criteria for PTSD or complex PTSD symptoms. We discuss the implications of a law enforcement tactic with traumatogenic potential used frequently in minority communities.

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Jorge Delva

University of Michigan

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Mark B. Padilla

Florida International University

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Pilar Horner

Michigan State University

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