Wolfgang Pitsch

Synthesis of a functionalized cyclohepten-one from erythronic acid-4-lactone

Abstract A convenient two-step synthesis of a functionalized and chiral cyclohepten-one 4 , which may serve as a useful building block in synthesis, is reported. The X-ray structure analysis of the intermediate hemiacetal 2 reveals the presence of a single anomer in the solid state, that equilibrates rapidly in solution.

Synthesis of a functionalized Diene-diyne from Butadiene-bis-epoxide

The synthesis of 5,6-dihydroxy-deca-3,7-diene-1,9-diyne from butadiene-bis-epoxide and propargylic alcohol is described.

Synthesis and structure of bicyclic enediynes ia twofold carbenoid ring closure

Macrobicyclic enediynes were obtained in four steps from dicarboxylic diesters. The key step of the synthesis is a twofold carbenoid ring closing procedure from acyclic precursors. Crystal structure analyses showed that bicyclo[6.6.4]dienetetrayne is not strained. Thermal analysis revealed its low thermal reactivity. An attempt to obtain bicyclo[6.6.2]dienetetrayne structures using the same method failed.

1,2:4,5-Di-O-isopropylidenegalactitol

The title compound, C12H22O6, is composed of two isopropylidene rings, one with approximate m symmetry and the other with approximate C2 symmetry, joined by an extended backbone. Hydrogen bonds connect the molecules into ribbons parallel to the y axis.